A5100762885- Dermatologic Treatments and Research
- Topological Materials and Phenomena
- Traumatic Brain Injury and Neurovascular Disturbances
- Ocular and Laser Science Research
- Photoacoustic and Ultrasonic Imaging
- Anesthesia and Neurotoxicity Research
- Neuroscience and Neuropharmacology Research
- Advanced Condensed Matter Physics
- Quantum many-body systems
- Ion channel regulation and function
- Intracranial Aneurysms: Treatment and Complications
- PARP inhibition in cancer therapy
- Thermoregulation and physiological responses
- Neurological Disease Mechanisms and Treatments
- Sympathectomy and Hyperhidrosis Treatments
- Optical Coherence Tomography Applications
- Pain Mechanisms and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Child Abuse and Related Trauma
- Optical Imaging and Spectroscopy Techniques
- Traumatic Brain Injury Research
- Receptor Mechanisms and Signaling
- Anesthesia and Sedative Agents
- Epilepsy research and treatment
- Stroke Rehabilitation and Recovery
Nanjing Agricultural University
2009-2025
University of Akron
2008-2024
Soochow University
2009-2024
First Affiliated Hospital of Wannan Medical College
2016-2024
Fudan University
2013-2023
Zhongshan Hospital
2013-2023
State Key Laboratory of Medical Neurobiology
2013-2023
Guangxi University of Chinese Medicine
2021-2022
Henan Institute of Technology
2021
Gansu Academy of Agricultural Sciences
2020
Coronavirus disease 2019 (COVID-19) has widely spread all over the world and numbers of patients deaths are increasing. According to epidemiology, virology, clinical practice, there varying degrees changes in patients, involving human body structure function activity participation. Based on World Health Organization (WHO) International Classification Functioning, Disability (ICF) its biopsychosocial model functioning, we use WHO Family Classifications (WHO-FICs) framework form an expert...
Mechanical allodynia can be evoked by punctate pressure contact with the skin (punctate mechanical allodynia) and dynamic stimulation induced gentle touching of (dynamic allodynia). Dynamic is insensitive to morphine treatment transmitted through spinal dorsal horn a specific neuronal pathway, which different from that for allodynia, leading difficulties in clinical treatment. K + -Cl − cotransporter-2 (KCC2) one major determinants inhibitory efficiency, system cord important regulation...
Background: This cross-sectional study aimed to investigate whether a long-term engagement in different types of physical exercise may influence resting-state brain networks differentially. In particular, we studied if there were differences functional connectivity measures when comparing older women who are practitioners tai chi chuan or walking. Method: We recruited 20 regularly practiced (TCC group), and 22 walked (walking group). Both the TCC group walking underwent magnetic resonance...
Although cryogen spray cooling (CSC) is used to minimize the risk of epidermal damage during laser dermatologic surgery, optimization current approach needed permit safe use higher light doses, which should improve therapeutic outcome in many patients. The objective this study was measure effect spurt duration (Δt) on heat transfer dynamics CSC using a model skin phantom. A fast-response temperature sensor constructed record changes surface CSC. Temperature measurements as function Δt at two...
Phenol red is widely used in cell culture as a pH indicator. Recently, it also has been reported to have estrogen-like bioactivity and be capable of promoting proliferation different lines. However, the effect phenol on primary neuronal never investigated. By using patch clamp technique, we demonstrated that hippocampal pyramidal neurons cultured neurobasal medium containing no had large depolarization-associated epileptiform bursting activities, which were rarely seen red-containing medium....
ABSTRACT Abusive head trauma (AHT) is the leading cause of death from in infants and young children. An AHT animal model was developed on 12-day-old mice subjected to 90° extension-flexion sagittal shaking repeated 30, 60, 80 100 times. The mortality time until return consciousness were dependent number repeats severity injury. Following 60 episodes shakings, pups demonstrated apnea and/or bradycardia immediately after Acute oxygen desaturation observed by pulse oximetry during respiratory...
Cryogen spray cooling (CSC) is a heat extraction process that protects the epidermis from thermal damage during dermatologic laser surgery.The objective of present work to investigate radial and temporal variations in transferred through surface skin phantom CSC.A fastresponse sensor used measure temperatures every 1 mm across 16 diameter sprayed phantom.An analytical expression based on Fourier's law Duhamel's theorem compute fluxes temperature measurements.Results show boundary conditions...
Energy deposition in bio-tissues is a prerequisite for the calculation of heat transfer during laser–tissue interactions. We calculated light propagation and energy using three-dimensional (3D) geometric Monte Carlo (MC) method, which uses mathematically defined geometrical relationship between photons tissue structures. demonstrated accuracy efficiency this method compared with voxel-based MC method: it was 25 times faster than VMC voxel size 10 µm. Results multi-coaxial vessel cluster...
Cryogen spray cooling (CSC) is used to minimize the risk of epidermal damage during laser dermatologic therapy. However, dominant mechanisms heat transfer transient process are incompletely understood. The objective this study elucidate physics CSC by measuring effect initial substrate temperature (T0) on dynamics. was delivered a straight-tube nozzle onto skin phantom. A fast-response thermocouple record phantom changes before, and after cryogen spray. Surface fluxes (q'') heat-transfer...
Catamenial epilepsy is a common phenomenon in female epileptic patients that is, part, influenced by the 17-β-estradiol level during menstrual cycle, which modulates strength of seizures. However, underlying mechanism(s) for catamenial remains unknown. In present study, effect 17‑β‑estradiol on modulating epileptiform activities was investigated cultured hippocampal neurons focusing transient outward potassium current. Using patch clamp technique, demonstrated to have dose‑dependent U‑shape...
We further support the notion that catechol-O-methyltransferase (COMT) polymorphism may play a role in cognitive function. A continuous visual 3-back numerical working memory task was performed for an hour among 21 patients with different COMT genotypes. P300 event-related potentials evoked from were first utilized to observe relationship between this and cortical physiology. The results showed Val/Met heterozygous individuals show poorer performance, lower amplitude, higher latency than...
Epilepsy is a common disease of the central nervous system. Tetanic spasms and convulsions are key symptoms exhibited during epileptic seizures. However, majority patients have significant post‑seizure silence following serious seizure; underlying molecular neural mechanisms in this burst interval unclear. The aim present study was to reveal effect role calcium‑activated potassium channels seizure period. Cyclothiazide (CTZ) used establish model rat hippocampal cultured neurons, then...
Purpose The purpose of this paper is to present a numerical analysis the laser surgery port wine stain (PWS) with cryogen spray cooling compare treatment effect between pulse dye and Nd:YAG laser, explain incomplete clear lesion optimize parameter.
Background Memantine is one of the important clinical medications in treating moderate to severe Alzheimer disease. The effect memantine on preventing or punctate allodynia has been thoroughly studied but not induction dynamic allodynia. aim this study investigate whether could prevent and its underlying spinal mechanisms. Results (1) In vivo spared nerve injury pain model, pretreatment with at a lower dose (10 nmol, intrathecal; memantine-10) selectively prevented (2) Pretreatment either...
East China Sea is one of the four sea areas in China, which possesses peculiar ecological environment and many kinds living creatures, especially microorganisms. We established microorganism library (during 2006–2010) for first time, stored about 30000 strains that covered most species. In this paper, 395 pure belong to 33 different genera were mainly introduced. Sulfitobacter , Halomonas Bacillus Pseudoalteromonas Idiomarina dominant On large‐scale biological activity screening strains, 100...