A5101515153- Pluripotent Stem Cells Research
- Congenital heart defects research
- Evolution and Genetic Dynamics
- Pharmacological Effects of Natural Compounds
- Bone health and treatments
- Pain Mechanisms and Treatments
- SARS-CoV-2 and COVID-19 Research
- vaccines and immunoinformatics approaches
- Bone health and osteoporosis research
- Liver Disease Diagnosis and Treatment
- Spine and Intervertebral Disc Pathology
- Diet and metabolism studies
- Virology and Viral Diseases
- Advanced Glycation End Products research
- Anesthesia and Pain Management
- Diet, Metabolism, and Disease
- Parathyroid Disorders and Treatments
- 3D Printing in Biomedical Research
- Drug Transport and Resistance Mechanisms
- Neuroinflammation and Neurodegeneration Mechanisms
- Per- and polyfluoroalkyl substances research
- Tissue Engineering and Regenerative Medicine
- Stress Responses and Cortisol
- Migraine and Headache Studies
- Pancreatic function and diabetes
First Affiliated Hospital of Fujian Medical University
2021-2024
Fujian Medical University
2021-2024
Guangzhou University of Chinese Medicine
2023-2024
Northeast Agricultural University
2021-2023
Princeton University
2022-2023
University of Chicago
2023
Fujian Institute of Microbiology
2021
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2020
Wenzhou Medical University
2020
Zhongshan Hospital
2019
Background Cardiometabolic index (CMI) is a novel indicator for predicting the risk of obesity-related diseases. We aimed to determine relationships CMI with insulin resistance (IR), impaired fasting glucose (IFG), and type 2 diabetes mellitus (T2DM) using NHANES data from 1999 2020. Methods After values were estimated, weighted univariate multivariate logistic regression analyses used ascertain whether was an independent IR, IFG, T2DM. Furthermore, stratified interaction carried out...
Identifying drivers of viral diversity is key to understanding the evolutionary as well epidemiological dynamics COVID-19 pandemic. Using rich genomic data sets, we show that periods steadily rising have been punctuated by sudden, enormous increases followed similarly abrupt collapses diversity. We introduce a mechanistic model saltational evolution with epistasis and demonstrate these features parsimoniously account for observed temporal inter-genomic Our results provide support recent...
Introduction Bats are important providers of ecosystem services such as pollination, seed dispersal, and insect control but also act natural reservoirs for virulent zoonotic viruses. host multiple viruses that cause life-threatening pathology in other animals humans but, themselves, experience limited pathological disease from infection. Despite bats’ importance several viruses, we know little about the broader viral diversity they host. Bat virus surveillance efforts challenged by...
To investigate the correlation between vibration sensory threshold (VPT) and renal function, including glomerulus tubule, in patients with type 2 diabetes mellitus (T2DM).
Although the study on regulatory mechanism of endothelial differentiation from perspective development provides references for cell (EC) derivation pluripotent stem cells, incomplete reprogramming and donor-specific epigenetic memory are still thought to be obstacles iPSCs clinical application. Thus, it is necessary establish a stable iPSC-EC induction system investigate differentiation. Based single-layer culture system, we successfully obtained ECs porcine (piPSCs). In vitro, derived...
Background Memantine is one of the important clinical medications in treating moderate to severe Alzheimer disease. The effect memantine on preventing or punctate allodynia has been thoroughly studied but not induction dynamic allodynia. aim this study investigate whether could prevent and its underlying spinal mechanisms. Results (1) In vivo spared nerve injury pain model, pretreatment with at a lower dose (10 nmol, intrathecal; memantine-10) selectively prevented (2) Pretreatment either...
Identifying drivers of viral diversity is key to understanding the evolutionary as well epidemiological dynamics COVID-19 pandemic. Using rich genomic data sets, we show that periods steadily rising have been punctuated by sudden, enormous increases followed similarly abrupt collapses diversity. We introduce a mechanistic model saltational evolution with epistasis and demonstrate these features parsimoniously account for observed temporal inter-genomic Our results provide support recent...
Recent studies have shown that the slightly elevated circulating levels of ketone bodies (KBs) played a significant role in treatment various diseases. This study is aimed at investigating association between different KBs and kidney function patients with type 2 diabetes mellitus (T2DM).A retrospective 955 T2DM (426 women 529 men) admitted to our hospital from December 2017 September 2019 was conducted. Patients were divided into groups line (low-normal group: 0.02-0.04 mmol/L,...
Abstract Background The bone mineral density (BMD) did not increase significantly after the normalization of serum thyroid hormone levels. Studies on effect muscle mass BMD in patients with Graves’ disease are scarce. This study aimed to determine association decreased reduced disease. Methods A total 758 at diagnosis (mean age 41.2 years) were enrolled for a cross-sectional study; these, 287 cohort median follow-up 24 months. Meanwhile, 1164 age- and sex-matched healthy controls...