A5020913782- Statistical Methods and Bayesian Inference
- Statistical Methods and Inference
- Pediatric Hepatobiliary Diseases and Treatments
- Maternal and Perinatal Health Interventions
- Helicobacter pylori-related gastroenterology studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Neonatal Respiratory Health Research
- Advanced Causal Inference Techniques
- Advanced Sensor and Control Systems
- Ovarian function and disorders
- Pregnancy and preeclampsia studies
- Educational Reforms and Innovations
- Metabolomics and Mass Spectrometry Studies
- Advanced Decision-Making Techniques
- Medical Research and Treatments
- Fatty Acid Research and Health
- Health Systems, Economic Evaluations, Quality of Life
- Gestational Diabetes Research and Management
- Birth, Development, and Health
- Menstrual Health and Disorders
- Cancer, Hypoxia, and Metabolism
- Cancer Research and Treatments
- Evaluation Methods in Various Fields
- Gut microbiota and health
- Metabolism and Genetic Disorders
Nanjing Agricultural University
2025
Minzu University of China
2024
University of Pennsylvania
2020-2024
Tsinghua University
2021
Cancer Research And Biostatistics
2020
Northeastern University
2014
Third People's Hospital of Huzhou
2014
Disruption of pulmonary vascular homeostasis is a central feature viral pneumonia, wherein endothelial cell (EC) death and subsequent angiogenic responses are critical determinants the outcome severe lung injury. A more granular understanding fundamental mechanisms driving reconstitution endothelium necessary to facilitate therapeutic repair. Here, we demonstrated that TGF-β signaling through TGF-βR2 (transforming growth factor–β receptor 2) activated in ECs upon influenza infection, mice...
Several adipokines are implicated in the pathophysiology of gestational diabetes mellitus (GDM), however, longitudinal data early pregnancy on many lacking. We prospectively investigated association a panel and mid-pregnancy with GDM risk.Within National Institute Child Health Human Development (NICHD) Fetal Growth Studies-Singletons cohort (n=2802), 10 (plasma fatty acid binding protein-4 (FABP4), chemerin, interleukin-6 (IL-6), leptin, soluble leptin receptor (sOB-R), adiponectin,...
Amino acids, fatty and acylcarnitine metabolites play a pivotal role in maternal fetal health, but profiles of these over pregnancy are not completely established. We described longitudinal trajectories targeted amino acylcarnitines pregnancy. quantified 102 combinations (37 37 28 acylcarnitines) plasma samples from pregnant women the Eunice Kennedy Shriver National Institute Child Health Human Development (NICHD) Fetal Growth Studies-Singletons cohort (n = 214 at 10-14 15-26 weeks, 107...
Abstract Introduction Polycystic ovary syndrome (PCOS) is associated with a wide range of unfavorable cardiometabolic risk factors, including obesity, hypertension, insulin resistance, impaired glucose metabolism, dyslipidemia, and metabolic syndrome. Compared women regular menstrual cycles, history irregular periods have an increased risk. Recently, the association between severity oligomenorrhea hyperinsulinemia resistance has been demonstrated. However, evidence linking cyclicity in PCOS...
Abstract The added value of candidate predictors for risk modeling is routinely evaluated by comparing the performance models with or without including predictors. Such comparison most meaningful when estimated two are both unbiased in target population. Very often data sourced from nonrepresentative convenience samples. Updating base model using study acknowledging discrepancy between underlying distribution and that population can lead to biased estimates therefore an unfair evaluation To...
Summary The two-phase study design is a cost-efficient sampling strategy when certain data elements are expensive and, thus, can only be collected on sub-sample of subjects. To date guidance how best to allocate resources within the has assumed that primary interest lies in estimating association parameters. When development and evaluation risk prediction tool, however, such may, fact, detrimental. resolve this, we propose novel for resource allocation based oversampling cases subjects who...