- Gestational Diabetes Research and Management
- Birth, Development, and Health
- Pregnancy and preeclampsia studies
- Obesity, Physical Activity, Diet
- Fatty Acid Research and Health
- Nutritional Studies and Diet
- Bariatric Surgery and Outcomes
- Maternal and Perinatal Health Interventions
- Maternal and fetal healthcare
- Breastfeeding Practices and Influences
- Pregnancy and Medication Impact
- Assisted Reproductive Technology and Twin Pregnancy
- Maternal Mental Health During Pregnancy and Postpartum
- Cancer Risks and Factors
- Metabolism and Genetic Disorders
- Coffee research and impacts
- Vitamin D Research Studies
- Metabolomics and Mass Spectrometry Studies
- Neonatal Respiratory Health Research
- Folate and B Vitamins Research
- Adipose Tissue and Metabolism
- Economic and Financial Impacts of Cancer
- Ovarian function and disorders
- Thyroid Disorders and Treatments
- Liver Disease Diagnosis and Treatment
University of Pennsylvania
2021-2025
University of Pennsylvania Health System
2024-2025
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2014-2023
National University of Singapore
2023
National Institutes of Health
2013-2022
Office of Extramural Research
2013-2022
Eunice Kennedy Shriver Center
2013-2022
California University of Pennsylvania
2022
Pennsylvania State University
2020
Glotech (United States)
2020
To estimate the prevalence of gestational weight gain adequacy according to 2009 Institute Medicine recommendations and examine demographic, behavioral, psychosocial, medical characteristics associated with inadequate excessive stratified by prepregnancy body mass index (BMI) category.We used cross-sectional, population-based data on women delivering full-term (37 weeks gestation or greater), singleton neonates in 28 states who participated 2010 2011 Pregnancy Risk Assessment Monitoring...
OBJECTIVE: To investigate whether prepregnancy obesity is associated with adverse pregnancy outcomes among women without chronic disease. METHODS: Singleton deliveries (N=112,309) mothers diseases in the Consortium on Safe Labor, a retrospective U.S. cohort, were analyzed using Poisson regression robust variance estimation. Relative risks and 95% confidence intervals (CIs) estimated perinatal relation to status adjusted for age, race–ethnicity, parity, insurance, smoking alcohol use during...
Nulliparity is associated with lower birthweight, but few studies have examined how within-mother changes in risk factors impact this association.We used longitudinal electronic medical record data from a hospital-based cohort of consecutive singleton live births 2002-2010 Utah. To reduce bias unobserved pregnancies, primary analyses were limited to 9484 women who entered nulliparous 2002-2004, 23,380 pregnancies up parity 3. Unrestricted secondary 101,225 45,212 7. We calculated gestational...
Both obesity and developmental disabilities have increased in recent decades. Limited studies suggest associations between maternal prepregnancy child neurodevelopment.
Artificial sweeteners are widely replacing caloric sweeteners. Data on long-term impact of artificially sweetened beverage (ASB) consumption during pregnancy offspring obesity risk lacking. We prospectively investigated intake ASBs and sugar-sweetened beverages (SSBs) in relation to growth through age 7 years among high-risk children born women with gestational diabetes.In a prospective study 918 mother-singleton child dyads from the Danish National Birth Cohort, maternal dietary was...
Abstract Objectives To evaluate the individual and combined associations of five modifiable risk factors with type 2 diabetes among women a history gestational mellitus examine whether these differ by obesity genetic predisposition to diabetes. Design Prospective cohort study. Setting Nurses’ Health Study II, US. Participants 4275 mellitus, repeated measurements weight lifestyle followed up between 1991 2009. Main outcome measure Self-reported, clinically diagnosed Five were assessed,...
Pregnancy complications are associated with increased risk of development cardiometabolic diseases and earlier mortality. However, much the previous research has been limited to White pregnant participants. We aimed investigate pregnancy in association total cause-specific mortality a racially diverse cohort evaluate whether associations differ between Black
ABSTRACT Background Postpartum haemorrhage (PPH) is associated with significant short‐term morbidity and mortality. Whether PPH confers long‐term all‐cause mortality risk unknown. Objective To examine the of PPH. Methods The Collaborative Perinatal Project (CPP) Mortality Linkage Study a prospective cohort study pregnant persons (1959–1966) linked vital status from National Death Index Social Security Master File for through 2016. was defined based on documentation within or after 24 hours...
Abstract Context T3 is the biologically active thyroid hormone involved in glucose metabolism. The free (fT3)/free T4 (fT4) ratio, a marker indicating conversion of fT4 to fT3, also implicated homeostasis. Objective To examine associations fT3 and fT3/fT4 ratio with gestational diabetes mellitus (GDM). Design In case-control study, markers (fT3, fT4, TSH) were measured was derived across four visits pregnancy, including first (gestational weeks 10 14) second (weeks 15 26) trimester....
OBJECTIVE To identify novel modifiable risk factors of gestational diabetes mellitus (GDM) by examining the association between prepregnancy habitual folate intake and GDM risk. RESEARCH DESIGN AND METHODS The study included 14,553 women in Nurses’ Health Study II who reported at least one singleton pregnancy 1991 2001 questionnaires. Prepregnancy intakes total folate, supplemental food were assessed using a frequency questionnaire administered every 4 years. Incident was ascertained from...
Nausea and vomiting during pregnancy have been associated with a reduced risk for loss. However, most prior studies enrolled women clinically recognized pregnancies, thereby missing early losses.To examine the association of nausea loss.A randomized clinical trial, Effects Aspirin in Gestation Reproduction, 1 or 2 losses at 4 US centers from June 15, 2007, to July 2011. This secondary analysis was limited confirmed by positive results human chorionic gonadotropin (hCG) test. symptoms were...