A5076750443- Neonatal Respiratory Health Research
- Neuroendocrine Tumor Research Advances
- Prenatal Screening and Diagnostics
- Birth, Development, and Health
- Lung Cancer Research Studies
- Congenital Heart Disease Studies
- Pregnancy and preeclampsia studies
- Genomic variations and chromosomal abnormalities
- Congenital Diaphragmatic Hernia Studies
- Gestational Diabetes Research and Management
- Epigenetics and DNA Methylation
- Sperm and Testicular Function
- Hemoglobinopathies and Related Disorders
- Reproductive Biology and Fertility
- Neuroblastoma Research and Treatments
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Bladder and Urothelial Cancer Treatments
- Blood groups and transfusion
- Monoclonal and Polyclonal Antibodies Research
- Respiratory viral infections research
- Iron Metabolism and Disorders
- Asthma and respiratory diseases
- RNA modifications and cancer
- Assisted Reproductive Technology and Twin Pregnancy
- Animal Virus Infections Studies
Nanjing Medical University
2014-2025
The First Affiliated Hospital, Sun Yat-sen University
2016-2025
Sun Yat-sen University
2016-2025
Suzhou Municipal Hospital
2021-2025
Children's Hospital of Fudan University
2015-2025
Jiangsu Province Hospital
2009-2024
Fujian Medical University
2012-2024
Shandong University of Traditional Chinese Medicine
2024
Central South University
2018-2024
Nanjing University of Chinese Medicine
2019-2024
Abstract Background Previous studies have showed clinical characteristics of patients with the 2019 novel coronavirus disease (COVID-19) and evidence person-to-person transmission. Limited data are available for asymptomatic infections. This study aims to present 24 cases infection screened from close contacts show transmission potential COVID-19 virus carriers. Methods Epidemiological investigations were conducted among all (or suspected patients) in Nanjing, Jiangsu Province, China, Jan 28...
Abstract Cutaneous squamous cell carcinoma represents the second most common cutaneous malignancy, affecting 7–11% of Caucasians in United States. The genetic determinants susceptibility to remain largely unknown. Here we report results a two-stage genome-wide association study carcinoma, totalling 7,404 cases and 292,076 controls. Eleven loci reached significance ( P <5 × 10 −8 ) including seven previously confirmed pigmentation-related loci: MC1R , ASIP TYR SLC45A2 OCA2 IRF4 BNC2 . We...
Background: Previous studies have showed clinical characteristics of patients with the 2019 novel coronavirus disease (COVID-19) and evidence person-to-person transmission. Limited data are available for asymptomatic infections. This study aims to present 24 cases infection screened from close contacts show transmission potential COVID-19 virus carriers. Methods: Epidemiological investigations were conducted among all (or suspected patients) in Nanjing, Jiangsu Province, China, Jan 28 Feb 9,...
Abstract Basal cell carcinoma (BCC) is the most common cancer worldwide with an annual incidence of 2.8 million cases in United States alone. Previous studies have demonstrated association between 21 distinct genetic loci and BCC risk. Here, we report results a two-stage genome-wide study BCC, totalling 17,187 287,054 controls. We confirm 17 previously reported identify 14 new susceptibility reaching significance ( P <5 × 10 −8 , logistic regression). These newly associated SNPs lie...
<h3>Importance</h3> Extreme prematurity is associated with a substantial burden on health care systems worldwide. However, little known about the prognosis of infants born extremely preterm in developing countries, such as China. <h3>Objective</h3> To describe survival and major morbidity among China over past decade. <h3>Design, Setting, Participants</h3> This retrospective cohort study was conducted from January 1, 2010, through December 31, 2019. Included individuals were gestational age...
Abstract Peptide toxins found in sea anemones venom have diverse properties that make them important research subjects the fields of pharmacology, neuroscience and biotechnology. This study used high-throughput sequencing technology to systematically analyze components tentacles, column, mesenterial filaments anemone Heteractis crispa , revealing diversity complexity different tissues. A total 1049 transcripts were identified categorized into 60 families, which 91.0% proteins 9.0% peptides....
Abstract Context T3 is the biologically active thyroid hormone involved in glucose metabolism. The free (fT3)/free T4 (fT4) ratio, a marker indicating conversion of fT4 to fT3, also implicated homeostasis. Objective To examine associations fT3 and fT3/fT4 ratio with gestational diabetes mellitus (GDM). Design In case-control study, markers (fT3, fT4, TSH) were measured was derived across four visits pregnancy, including first (gestational weeks 10 14) second (weeks 15 26) trimester....
Thalassemia and hemoglobinopathy are two common inherited disorders, which highly prevalent in southern China. However, there is little knowledge on the genotypes of thalassemia Southeastern In this study, we present a large-scale genetic detection molecular characterization Fujian province, A total 189414 subjects screened for were recruited, hemoglobin components levels investigated. Furthermore, suspected was identified, rare forms thalassemias detected. Among screened, overall prevalence...
Chapparvovirus, a recently determined new genus in the family Parvoviridae, can infect many species of animals including bats, chickens, and pigs. Here, using viral metagenomics method, we identified novel Chapparvovirus from feces wild rats designated it as rat parvovirus 2 (RPV2). The nearly complete genome RPV2 is 4222-nt long includes two ORFs encoding 654-aa nonstructural protein 1 (NS1) 472-aa capsid (VP), respectively. Phylogenetic analysis over amino acid sequence NS1 showed that...
Despite dietary recommendations of polyunsaturated fatty acids (PUFAs) for cardiometabolic health, n-3 and n-6 PUFAs their interplay in relation to diabetes risk remain debated. Importantly, data among pregnant women are scarce. We investigated individual plasma phospholipid early midpregnancy subsequent gestational mellitus (GDM).Within the National Institute Child Health Human Development (NICHD) Fetal Growth Studies-Singleton Cohort (n = 2,802), levels were measured at weeks (GWs) 10-14,...
It has been consistently shown in several meta-analyses that infants born after ART have an excess of birth defects compared with those spontaneous conception, however, the prevalence among offspring China is incompletely studied. Moreover, it unclear to what extent risk associated parental infertility characteristics, specific procedures and twinning.In prospective cohort study, we included women who participated cohort, had pregnancies at least 20 gestational weeks between August 2016 May...
Exposure to PM
Abstract Background Gastroenteropancreatic neuroendocrine neoplasm (GEP-NEN) is the most common type of tumors accounting for 65–75% neoplasms (NENs). Given fact that there are few studies on GEP-NENs among Chinese patients, we performed a retrospective study in South China. Methods Totally 178 patients with treated at First Affiliated Hospital Sun Yat-sen University between January 1995 and May 2012 were analyzed retrospectively. Results Pancreas was found site involvement (34.8%). 149...
Chromogranin A (CgA) not only plays an important role in pathologic diagnosis, but is also used as a circulating biomarker patients with gastroenteropancreatic neuroendocrine neoplasm (GEP-NEN). However, the relationship between immunohistochemistry (IHC) expression and serum levels of CgA has been investigated. The value for evaluating treatment response prognosis still well understood. We conducted this study to assess significance GEP-NEN terms curative effects evaluation prognosis. One...