- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Energy and Environment Impacts
- Air Quality Monitoring and Forecasting
- Heavy Metal Exposure and Toxicity
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Atmospheric chemistry and aerosols
- Toxic Organic Pollutants Impact
- Effects and risks of endocrine disrupting chemicals
- Occupational and environmental lung diseases
- Biomarkers in Disease Mechanisms
- Climate variability and models
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Mercury impact and mitigation studies
- Statistical Methods and Inference
- Sperm and Testicular Function
- Advanced Statistical Methods and Models
- Health, Environment, Cognitive Aging
- Heavy metals in environment
- Lightning and Electromagnetic Phenomena
- Atmospheric aerosols and clouds
- Optical Systems and Laser Technology
- Bayesian Methods and Mixture Models
- Advanced Measurement and Detection Methods
Hebei Medical University
2014-2025
China Medical University
2024
First Hospital of China Medical University
2024
Hohai University
2024
Henan Normal University
2024
University of Hong Kong
2020-2023
First Hospital of Jilin University
2023
Jilin University
2023
Northwest A&F University
2011-2023
Southwest Medical University
2023
Although major concerns exist regarding the potential consequences of human exposures to nanoscale carbon black (CB) particles, limited toxicological data is currently available. The purpose this study was evaluate if CB particles could be responsible, at least partially, for altered lung function and inflammation observed in workers exposed particles.Scanning Electron Microscopy (SEM), Transmission (TEM), Brunauer-Emmett-Teller were used characterize CB. Eighty-one CB-exposed male 104...
The influence of air pollution on human health has sparked widespread concerns across the world. Previously, we found that exposure to ambient fine particulate matter (PM2.5) in our "real-ambient exposure" system can result reduced lung function. However, mechanism organ-specific toxicity is still not fully elucidated. balance microbiome contributes maintaining and gut health, but changes under PM2.5 are understood. Recently, crosstalk between nuclear factor E2-related 2 (Nrf2) was reported....
Exposure to PM
Sooty blotch and flyspeck (SBFS) fungi colonize the surface wax layer of fruit apple, pear, persimmon, banana, orange, papaya, several other cultivated tree vine crops. In addition to colonizing crops, SBFS also grow on surfaces stems, twigs, leaves, a wide range wild plants. The disease occurs worldwide in regions with moist growing seasons. is regarded as serious by growers plant pathologists because it can cause substantial economic damage. smudges stipples often result downgrading from...
To assess the carcinogenic potential of PM2.5 exposure, we developed a cell-based experimental protocol to examine cell transformation activity samples from different regions in China. The seasonal ambient were collected three megacities, Beijing (BJ), Wuhan (WH), and Guangzhou (GZ), November 2016 October 2017. mean concentrations much higher winter season (BJ: 109.64 μg/m3, WH: 79.99 GZ: 49.99 μg/m3) than that summer 42.40 25.82 19.82 μg/m3). organic extracts (OE) combined (S) (June, July,...
Background: Recent years, there occurs heavy haze pollution in northern China during wintertime. The potential influence of airborne particulate matter (PM) on human health attracts great concern. fuel-derived PM the inhalable size range is dominated by aggregates nanoparticles Carbon black (CB). However, are still lack evidences especially regarding long-term exposure to explain chronic effects nanoscaled CB and relative mechanism. Purpose: objective this study was identify mechanism...
Abstract Extreme precipitation events over the North China Plain (NCP) in midsummer during 1979–2016 are classified into two types using objective cluster analysis: a northern pattern with heavy and central–southern relatively moderate precipitation. The large‐scale circulation patterns responsible for extreme then determined. In NCP type, accompanies zonal gradient between an anomalous low‐pressure system at high latitudes westward‐ northward‐extended western Pacific subtropical (WNPSH)....
Pulmonary space-occupying lesions are typical chronic pulmonary diseases that contribute significantly to healthcare resource use and impose a large disease burden in China. A time-series ecological trend study was conducted investigate the associations between environmental factors hospitalizations for North of China from 2014 2022. The DLNM used quantify association with lung cancer admissions. heating-, age-, gender-, malignancy-specific effects were further estimated identify susceptible...
It is generally accepted that exposure to particulate matter (PM) increases the risk of cardiovascular-related morbidity and mortality, though exact mechanism behind this has yet be elucidated. Oxidative stress plays a potentially important role in toxicity, with Nrf2 serving as major antioxidant gene. In current study, knockout mouse model was used combination an individual ventilated cage (IVC)-based real-ambient PM system assess potential cardiotoxicity induced by related signaling...
Previous studies have shown that long-term exposure to fine particulate matter (PM 2.5 ) increases the morbidity and mortality of pulmonary diseases such as asthma, chronic obstructive disease emphysema. Oxidative stress inflammation play key roles in damage caused by PM . Nuclear factor erythroid 2-related 2 (Nrf2) could regulate expression antioxidant anti-inflammatory genes is pivotal for protection against -induced oxidative stress. In this study, a real-ambient system was constructed...
Long-term exposure to fine particulate matter (PM2.5) increases susceptibility chronic respiratory diseases, including inflammation and interstitial fibrosis. However, the regulatory mechanisms by which immune response mediates initiation of pulmonary fibrosis has yet be fully characterized. This study aimed illustrate interplay between different cell clusters key pathways in triggering lung injuries mice following PM exposure.Six-week-old C57BL/6J male were exposed or filtered air for 16...