A5054885563- Birth, Development, and Health
- Metabolomics and Mass Spectrometry Studies
- Obesity, Physical Activity, Diet
- Nutritional Studies and Diet
- Gestational Diabetes Research and Management
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Psychosomatic Disorders and Their Treatments
- Pregnancy and preeclampsia studies
- Diet and metabolism studies
- Diet, Metabolism, and Disease
- Complementary and Alternative Medicine Studies
- Genetic Associations and Epidemiology
- Breastfeeding Practices and Influences
- Potato Plant Research
- Pregnancy and Medication Impact
- Fatty Acid Research and Health
- Musculoskeletal pain and rehabilitation
- Bariatric Surgery and Outcomes
- Child Nutrition and Water Access
- Heart Rate Variability and Autonomic Control
- Cancer-related molecular mechanisms research
- Nuts composition and effects
- Consumer Attitudes and Food Labeling
- Lipid metabolism and disorders
- Liver Disease Diagnosis and Treatment
Frederiksberg Hospital
2021-2025
Center for Clinical Research and Prevention
2021-2025
Copenhagen University Hospital
2022-2025
Statens Serum Institut
2016-2025
UK Research and Innovation
2024
University of Copenhagen
2017-2024
Medical Research Council
2024
University of Zurich
2024
European Union
2024
Research England
2024
Artificial sweeteners are widely replacing caloric sweeteners. Data on long-term impact of artificially sweetened beverage (ASB) consumption during pregnancy offspring obesity risk lacking. We prospectively investigated intake ASBs and sugar-sweetened beverages (SSBs) in relation to growth through age 7 years among high-risk children born women with gestational diabetes.In a prospective study 918 mother-singleton child dyads from the Danish National Birth Cohort, maternal dietary was...
Abstract Objective To investigate the association between adolescents’ dietary quality and presence of painful temporomandibular disorder (p‐TMD) headaches in young adulthood. Background P‐TMD is a common orofacial pain condition often associated with discomfort. Some studies have shown that behaviors can impact chronic musculoskeletal pain. Although various factors such as sex, age, psychosocial aspects, sensitivity contribute to p‐TMD, role nutrition remains unclear. Methods The 32,247...
OBJECTIVE To identify novel modifiable risk factors of gestational diabetes mellitus (GDM) by examining the association between prepregnancy habitual folate intake and GDM risk. RESEARCH DESIGN AND METHODS The study included 14,553 women in Nurses’ Health Study II who reported at least one singleton pregnancy 1991 2001 questionnaires. Prepregnancy intakes total folate, supplemental food were assessed using a frequency questionnaire administered every 4 years. Incident was ascertained from...
Objective Women with a history of gestational diabetes mellitus (GDM) have an exceptionally high risk for type 2 (T2D). Yet, little is known about genetic determinants T2D in this population. We examined the association score (GRS) two independent populations women GDM and how might be modified by non-genetic T2D. Research design methods This cohort study included 2434 white from Nurses’ Health Study II (NHSII, n=1884) Danish National Birth Cohort (DNBC, n=550). A GRS was calculated using 59...
Abstract Background The association between maternal dietary patterns during pregnancy and offspring’s risk of paediatric-onset inflammatory bowel disease (pIBD) is largely unknown. Therefore, we explored this link in mother-child dyads from the Danish National Birth Cohort (DNBC). Methods DNBC a nationwide cohort pregnant mothers Denmark enrolled 1996 2002. In gestational week 25, food frequency questionnaire assessed intakes >360 foods previous four weeks. were divided into 37...
Abstract Background A key question remains unanswered: whether maternal consumption of fish and oil supplements during pregnancy is associated with the risk early childhood inflammatory bowel disease (IBD) in offspring. This association was examined present study. Methods Data from Danish National Birth Cohort (1996–2002) were used, which collected dietary data using a food frequency questionnaire (FFQ), Patient Registry to identify IBD cases. The study included mother-child dyads mother had...
Abstract Artificial sweeteners are used to reduce energy intake, but studies suggest that consumption during pregnancy may impact the offspring’s risk of overweight. In this longitudinal cohort study, we aimed examine association between artificially sweetened or sugar-sweetened beverages and offspring overweight from birth 18 years in Danish National Birth Cohort (DNBC). 101,042 pregnancies were enrolled DNBC 1996-2002. Follow-up was conducted throughout pregnancy, childhood, adolescence....
Regular physical activity (PA) protects against several non-communicable diseases. However, there is social inequality in PA and low adherence to recommendations. We investigated whether maternal socioeconomic status (SES) pregnancy are associated with sport-related level 14-year-old offspring. Self-reported from 23 753 mother-child dyads the Danish National Birth Cohort was retrieved Weekly hours of were dichotomized into fulfilling official recommendations 30 min/day for adults 60 children...
Background: Vitamin K is a cofactor necessary for the biological activity of proteins like Matrix Gla Protein (MGP), which reduce calcification and help preserve lung function. This study aims to determine, first, whether low vitamin status associated with chronic obstructive pulmonary disease (COPD), secondary, level COPD severity, smoking exposure, or mortality. Methods: The plasma concentration dephosphorylated uncarboxylated (dp-uc) MGP was used as an inverse biomarker in 98 patients...
Background The Developmental Origins of Health and Disease (DOHaD) hypothesis postulates that exposures during early life, such as maternal dietary intake pregnancy, may have a lifelong impact on the individual's susceptibility to diseases. own lifestyle habits are obviously an additional factor, but we only limited knowledge regarding how it interact with prenatal in determining later disease. To gain further insight into these potentially complex relationships, examined longitudinal...
Objectives It has been hypothesised that functional somatic disorders (FSD) could be initiated by sympathetic predominance in the autonomic nervous system as measured low heart rate variability (HRV). Earlier studies on association between HRV and FSD are small case–control hampered selection bias do not consider great overlap various FSDs. The aim of present study is to assess any associations FSDs whether chronic stress confounds such an association. Design A cross-sectional general...
Artificially sweetened beverages (ASBs) are commonly consumed and recommended for individuals at high risk cardiometabolic diseases; however, the health effects of ASBs remain contradictory. Given that cross-sectional analyses subject to reverse causation, prospective studies with long-term follow-up needed evaluate associations between health, especially among high-risk individuals.
With increased focus on dietary intake among youth and risk of diseases later in life, it is importance, prior to assessing diet-disease relationships, examine the validity assessment tool. This study's objective was evaluate relative a self-administered web-based FFQ Danish children aged 12 15 years. From nested sub-cohort within National Birth Cohort, 124 adolescents participated. Four weeks after completion FFQ, were invited complete three telephone-based 24HRs; administered 4 apart. Mean...
Background: Iron overload has been associated with diabetes. Studies on iron exposure during pregnancy and in early life risk of childhood type 1 diabetes (T1D) are sparse. We investigated whether supplementation were T1D. Methods: In a case-cohort design, we identified up to 257 children T1D (prevalence 0.37%) from the Danish National Birth Cohort through linkage Childhood Diabetes Register. The primary was maternal pure (yes/no) as reported interview two at 30 weeks gestation (n = 68,497...
Fetal exposure to gestational diabetes mellitus (GDM) increases the risk of metabolic diseases in offspring. Leptin, adiponectin, and fibroblast growth factor 21 (FGF21) may play potential roles underlying disease mechanisms. We investigated impact fetal GDM on leptin, FGF21 concentrations their associations with measures adiposity traits during childhood/adolescence.The follow-up study included 504 540 control offspring aged 9-16 from Danish National Birth Cohort. Anthropometric...
Abstract Objective Food frequency questionnaires are relatively inexpensive, easy and quick to administer, but the construction of a food questionnaire that can capture Chinese habits is challenging given diverse lifestyle eating in different parts country. The aim this study was assess validity reproducibility self‐administered against 3‐day dietary recall rural region western China. Design Prospective cohort study. Setting maternal child healthcare hospital. Population A total 168 healthy...