A5043718951- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Global Health Care Issues
- Birth, Development, and Health
- Gestational Diabetes Research and Management
- Pregnancy and preeclampsia studies
- Pregnancy and Medication Impact
- HIV Research and Treatment
- Assisted Reproductive Technology and Twin Pregnancy
- HIV-related health complications and treatments
- Asthma and respiratory diseases
- Acute Myeloid Leukemia Research
- Breastfeeding Practices and Influences
- Memory and Neural Mechanisms
- Energy and Environment Impacts
- Bariatric Surgery and Outcomes
- Eosinophilic Esophagitis
- Reproductive Health and Technologies
- Atmospheric chemistry and aerosols
- HIV/AIDS Research and Interventions
- Memory Processes and Influences
- Neural and Behavioral Psychology Studies
- Ectopic Pregnancy Diagnosis and Management
- Toxic Organic Pollutants Impact
- Neonatal Respiratory Health Research
Emmes (United States)
2016-2025
Stanford University
2024
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2013-2020
Alkermes (Ireland)
2012-2019
University of California, Merced
2019
National Institutes of Health
2017
Boston University
2001-2006
Athinoula A. Martinos Center for Biomedical Imaging
2006
University of Southern California
1991-1992
The Aerospace Corporation
1991
Abstract Lesions of parahippocampal structures impair performance delayed matching tasks in nonhuman primates, suggesting a role for these the maintenance items working memory and short‐term stimulus matching. However, most human functional imaging studies have not shown medial temporal activation during primarily focused on magnetic resonance (fMRI) signal intensity changes prefrontal posterior parietal cortex. The goal this study was to test hypothesis that difference between primate data...
Replicating HIV-1 in the brain is present HIV encephalitis (HIVE) and microglial nodule (MGNE) putatively linked with HIV-associated neurocognitive disorders (HAND). A cliniconeurovirological correlation was conducted to elucidate relationship between viral load clinical phenotype. SUBJECTS AND ASSAYS: gag/pol RNA DNA copies were quantified reverse transcriptase-polymerase chain reaction or polymerase 148 HAART-era specimens. Comparison HAND, HIVE, MGNE neuropsychological (NP) test scores...
Background:Extreme temperature is associated with adverse birth outcomes but it unclear whether increases early delivery risk.Objectives:We aimed to determine the association between ambient and delivery.Methods:Medical records from 223,375 singleton deliveries 12 U.S. sites were linked local temperature. Exposure hot (> 90th percentile) or cold (< 10th using site-specific window-specific distributions defined for 3-months preconception, 7-week periods during first two trimesters, 1...
Background: Climate change is expected to have adverse health effects, but the association between extreme ambient temperatures and stillbirth unclear. Objectives: We investigated acute chronic associations risk, estimated attributable risk associated with local temperature extremes in United States. Methods: linked 223,375 singleton births ≥23 weeks of gestation (2002–2008) from 12 U.S. sites temperature. Chronic exposure hot (>90th percentile), cold (<10th or mild (10th–90th percentile)...
Importance An emerging paradigm attributes third-trimester fetal growth deceleration in uncomplicated twin pregnancies to an evolutionary adaptive process. Evaluating longitudinal soft-tissue development may provide important insights into differential trajectories between twins and singletons. Objective To compare vs singleton lean fat tissue across pregnancy. Design, Setting, Participants Prospective cohort study of dichorionic singletons with serial ultrasound scans chart (2009-2013)...
Experimental data and computational models suggest that blockade of muscarinic cholinergic receptors impairs paired-associate learning increases proactive interference (E. DeRosa & M. E. Hasselmo, 2000; Hasselmo J. Bower, 1993). The results presented here provide evidence in humans supporting these hypotheses. Young healthy subjects first learned baseline word pairs (A-B) and, after a delay, additional overlapping (A-C) nonoverlapping (D-E) pairs. As predicted, when compared with who...
<b>Objective: </b> To investigate the integrity of hippocampal-prefrontal circuitry during episodic encoding in patients with HIV. <b>Methods: Functional MRI was used to observe changes blood oxygenation level-dependent (BOLD) signal 14 HIV-positive participants and age- education-matched control subjects while performing an task. Subjects also completed neuropsychological measures attention memory. <b>Results: Behavioral results revealed no significant differences performance. The fMRI that...
Although ambient air pollution may increase hypertension risk through endothelial damage and oxidative stress, evidence is inconsistent regarding its effect on in pregnancy. Prior research has evaluated a limited scope of species often not differentiated preeclampsia, which have placental origin, from gestational hypertension. Among 49 607 women with at least 2 singleton deliveries the Eunice Kennedy Shriver National Institute Child Health Human Development Consecutive Pregnancies Study...
Eight subjects studied a set of complex visual images after administration 0.4 mg scopolamine. Another 8 performed the same task without drug administration. On subsequent item recognition test, rated, on 5-point scale, their confidence that pictures and an equal number unstudied lures were actually presented. Results showed scopolamine affected responses to items, but not lures, demonstrating unambiguous effect memory. To describe scopolamine-injected subjects' data, authors constructed new...
Extreme ambient temperatures have been linked to preterm birth. Preterm premature rupture of membranes is a common precursor birth but rarely studied in relation temperature.We 15,381 singleton pregnancies with from nationwide US obstetrics cohort (2002-2008) local temperature. Case-crossover analyses compared daily temperature during the week preceding delivery and day 2 control periods, before after case period. Conditional logistic regression models calculated odds ratio (OR) 95%...
Objective Women with a history of gestational diabetes mellitus (GDM) have an exceptionally high risk for type 2 (T2D). Yet, little is known about genetic determinants T2D in this population. We examined the association score (GRS) two independent populations women GDM and how might be modified by non-genetic T2D. Research design methods This cohort study included 2434 white from Nurses’ Health Study II (NHSII, n=1884) Danish National Birth Cohort (DNBC, n=550). A GRS was calculated using 59...
Purpose Women who experience gestational diabetes mellitus (GDM) are at exceptionally high-risk of developing type 2 (T2DM) later in life. However, limited information is available about genetic and environmental factors that implicated the progression from GDM to T2DM. Participants The Diabetes & Women’s Health (DWH) Study applied a hybrid design, which combined new prospective data collection with existing two cohorts, Danish National Birth Cohort (DNBC) Nurses’ II (NHS II). In total,...
Abstract Purpose The use of telemedicine (TM) has accelerated in recent years, yet research on the implementation and effectiveness TM‐delivered medication treatment for opioid disorder (MOUD) been limited. This study investigated feasibility implementing a care coordination model involving MOUD delivered via an external TM provider purpose expanding access to patients rural settings. Methods tested 6 primary sites by establishing referral between clinic company MOUD. intervention spanned...