A5069452106- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Cardiac Valve Diseases and Treatments
- Heart Failure Treatment and Management
- Cystic Fibrosis Research Advances
- Cardiac electrophysiology and arrhythmias
- Cardiac and Coronary Surgery Techniques
- Congenital Heart Disease Studies
- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiovascular and exercise physiology
- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiomyopathy and Myosin Studies
- Sexual function and dysfunction studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Traumatic Brain Injury Research
- Infective Endocarditis Diagnosis and Management
- Heart Rate Variability and Autonomic Control
- Neonatal Respiratory Health Research
- Influenza Virus Research Studies
- Hormonal and reproductive studies
Gentofte Hospital
2013-2025
University of Copenhagen
2016-2025
Copenhagen University Hospital
2020-2024
Rigshospitalet
2020
Lund University
2000
Purpose: This study of patients with minor head injury was designed to investigate the relation S-100 protein measurements computed tomograpy (CT) findings and outcomes. Increased serum levels this were hypothetized predict intracranial pathology increased frequency post-concussion symptoms. Methods: One hundred eighty-two studied Glasgow Coma Scale scores 13-15. The recruited from three Scandinavian neurotrauma centres. Serum measured at admittance CT scans brain obtained within 24 hours...
ABSTRACT Background Influenza infection has been associated with multiple cardiac complications including acute heart failure and myocardial infarction. The FluHeart study aims to uncover the potential effect of influenza on structure function as assessed by echocardiography during hospitalization. Methods This prospective cohort included hospitalized patients 2021–2022 season. Participants underwent using a prespecified protocol. were successfully matched 1:1:1 age, sex, status controls...
Background: Vitamin K is a cofactor necessary for the biological activity of proteins like Matrix Gla Protein (MGP), which reduce calcification and help preserve lung function. This study aims to determine, first, whether low vitamin status associated with chronic obstructive pulmonary disease (COPD), secondary, level COPD severity, smoking exposure, or mortality. Methods: The plasma concentration dephosphorylated uncarboxylated (dp-uc) MGP was used as an inverse biomarker in 98 patients...
Abstract Aims Quantification of systolic function in patients with atrial fibrillation (AF) is challenging. A novel approach, based on RR interval correction, to counteract the varying heart cycle lengths AF has recently been proposed. Whether this method superior failure (HFrEF) remains unknown. This study investigates prognostic value interval‐corrected peak global longitudinal strain {GLSc = GLS/[RR^(1/2)]} relation all‐cause mortality HFrEF displaying during echocardiographic...
It is often difficult to provide an exact echocardiographic measure of left ventricular systolic function in patients with atrial fibrillation, partly because the varying cycle length affecting pre and afterload increased heart rate accompanying this arrhythmia. We sought elucidate two points: whether it would be possible correct for cyclic variance output, if global longitudinal strain preferable ejection fraction at evaluating during fibrillation.
Tissue Doppler Imaging (TDI) detects early signs of left ventricular dysfunction. The prognostic potential TDI in patients with atrial fibrillation (AF) has, however, not yet been clarified. This study evaluates the value fibrillation.In total, echocardiograms from 313 AF during examination were analyzed offline. Longitudinal systolic velocity (s'), diastolic (e') and longitudinal displacement (LD) measured by color TDI. During a median follow-up 891 days, 64 (20%) died. was significantly...
Abstract Aims The prognostic value of myocardial performance index (MPI) has not yet been assessed in patients with atrial fibrillation (AF). aim this study was to evaluate the MPI by tissue Doppler imaging (TDI) M-mode AF patients. Methods and results Echocardiograms from 210 during examination were analysed offline. Patients known heart failure (HF) excluded. Time intervals measured using an line through mitral valve leaflets provide a colour diagram leaflet movement so all time could be...
Chronic Obstructive Pulmonary Disease (COPD) exacerbation is known for its substantial impact on morbidity and mortality among affected patients, creating a significant healthcare burden worldwide. Coagulation abnormalities have emerged as potential contributors to pathogenesis, raising concerns about increased thrombotic events during exacerbation. The aim of this study was explore the differences in thrombelastography (TEG) parameters coagulation markers COPD patients admission with at...
Abstract Background Cystic fibrosis (CF) is an autosomal recessive disease affecting multiple organs, however the extent of cardiac involvement in CF yet to be determined. The remarkable therapeutic advancements with new highly effective transmembrane conductance regulator (CFTR) modulator treatment and subsequent increase life expectancy substantiates further research. Purpose We aimed explore prevalence abnormalities potential subclinical alterations structure function adults compared...
Abstract Background Cystic fibrosis (CF) is an autosomal recessive disease affecting multiple organs. Emerging evidence indicates elevated risk of cardiovascular complications in people with CF (pwCF), some studies implicating CF-related cardiomyopathy as underlying mechanism. Whether screening for cardiac symptoms and N-terminal pro B-type natriuretic peptide (NT-proBNP) levels may aid identifying impairment pwCF remains unknown. Purpose To assess prevalence dyspnea chest pain investigate...
Abstract Background Emerging evidence suggests that the pathogenesis of atrial fibrillation (AF) is affected by inflammatory processes which contribute to structural and electrical remodeling atria, creating a substrate for arrythmia. Aim To assess whether inflammation measured C-reactive protein (CRP) associated with readmission direct current (DC) cardioversion, ablation, heart failure or stroke after discharge from 1st time DC cardioversion. Methods This nationwide retrospective cohort...
Aims: This study evaluates the prognostic value of strain in patients with atrial fibrillation (AF) and suggests a novel approach on how to take into account varying heart cycle lengths AF. Methods: Echocardiograms from 204 AF during examination were analyzed. Peak global longitudinal (GLS) was averaged apical 4-chamber, 2-chamber long axis view. To adjust for lengths, we indexed measurements square root RR-interval, (GLS/√(RR)). The combined end-point included incident failure, stroke,...
Abstract Background The presence of aortic valve (AV) sclerosis and non-severe stenosis has been a suggested marker cardiovascular risk, but whether AV is independently associated with increased risk or coexistent factors remains to be clarified. Objective We examined clinical characteristics prognosis the in general population. Methods A total 4,466 participants from prospective cohort study population were included. Patients insufficient image quality (n=119) known heart failure (n=130)...
Abstract Background Global longitudinal strain is a well-established prognosticator of heart failure (HF) in the general population. The prognostic values regional left ventricular (LV) basal, mid and apical regions remain unexplored Purpose purpose this study was to investigate relationship between LV incident HF Methods This prospective cohort included randomly selected citizens from major metropolitan area. All participants were examined with echocardiography. outcome HF. Participants...
Introduction: Cardiac power (CP) integrates echocardiographic and clinical parameters of hemodynamics, but the prognostic value CP in general population remains to be established. Hypothesis: This study investigates association between incident heart failure (HF) cardiovascular (CV) mortality Methods: A total 4,022 participants without known HF from a cohort was included study. calculated by cardiac output x mean blood pressure 0.222. expressed W/100 g LV myocardium. The composite outcome or...