A5062033710- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Pulmonary Hypertension Research and Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cystic Fibrosis Research Advances
- Cardiovascular Disease and Adiposity
- Heart Rate Variability and Autonomic Control
- Cardiac Valve Diseases and Treatments
- Neonatal Respiratory Health Research
- Cardiovascular Health and Disease Prevention
- Cardiac Arrhythmias and Treatments
- HIV-related health complications and treatments
- Cardiac tumors and thrombi
- Congenital Heart Disease Studies
- Cardiovascular and exercise physiology
- Ultrasound in Clinical Applications
Copenhagen University Hospital
2024
University of Copenhagen
2020-2024
Gentofte Hospital
2020-2024
Brigham and Women's Hospital
2023
Harvard University
2023
Left atrial (LA) strain parameters have been demonstrated to be valuable predictors of fibrillation (AF) in several patient cohorts. The purpose this study was investigate whether LA strain, assessed by two-dimensional speckle-tracking echocardiography, can used predict the development AF general population.This prospective longitudinal included 4466 participants from fifth Copenhagen City Heart Study. All underwent a health examination, including echocardiographic measurements strain....
Abstract Background Early recognition of cardiac dysfunction in patients with chronic obstructive pulmonary disease (COPD) may prevent future impairment and improve prognosis. Quantitative assessment subsegmental segmental vessel volume by Computed Tomographic (CT) imaging can provide a surrogate vascular remodeling. We aimed to examine the relationship between lung segmental- volume, echocardiographic measures structure function COPD. Methods studied 205 participants COPD, included large...
Abstract Aims Measures of left atrial (LA) function are known to predict both ischaemic stroke and fibrillation in specific patient groups. The aim this study was investigate the value LA reservoir strain for predicting patients undergoing coronary artery bypass grafting (CABG) whether presence postoperative (POAF) modified relationship. Methods results Patients isolated CABG were included. primary endpoint stroke. association between investigated uni- multivariable Cox proportional hazards...
Pulmonary vascular abnormalities, quantified from computed tomography scans, have frequently been observed in patients with pulmonary diseases. However, little is known about changes cardiac disease. Thus, we aimed to examine the cardiopulmonary relation atrial fibrillation (AF) by comparing volume (PVV) echocardiographic measures and AF severity. A total of 742 (median age 63 years, 70% men) who underwent ablation for were included. Preprocedural was used measure small-vessel PVV, along...
Abstract Background Chronic obstructive pulmonary disease (COPD) is common and strongly associated with cardiovascular disease, but the pathophysiology has not been fully elucidated. Purpose We aimed to investigate cardiac structure function in patients COPD compared a matched general population. Methods In prospective cohort study, 796 were included 1:2 on age sex controls from population study. All participants underwent an examination program including echocardiography. Standardized...
Abstract Background Cystic fibrosis (CF) is an autosomal recessive disease affecting multiple organs. Emerging evidence indicates elevated risk of cardiovascular complications in people with CF (pwCF), some studies implicating CF-related cardiomyopathy as underlying mechanism. Whether screening for cardiac symptoms and N-terminal pro B-type natriuretic peptide (NT-proBNP) levels may aid identifying impairment pwCF remains unknown. Purpose To assess prevalence dyspnea chest pain investigate...
Abstract Background Cystic fibrosis (CF) is an autosomal recessive disease affecting multiple organs, however the extent of cardiac involvement in CF yet to be determined. The remarkable therapeutic advancements with new highly effective transmembrane conductance regulator (CFTR) modulator treatment and subsequent increase life expectancy substantiates further research. Purpose We aimed explore prevalence abnormalities potential subclinical alterations structure function adults compared...
Abstract Background Emerging evidence indicates the coexistence pulmonary fibrosis and emphysema in patients with Chronic Obstructive Pulmonary Disease (COPD). The effect of on cardiac structure function COPD remains unclear. Purpose This study aimed to examine association between degree identified Computed Tomographic (CT) imaging echocardiographic measures individuals COPD. Methods included 456 COPD, participating a large prospective cohort study. Patients available CT scans...
Abstract Background Human Immunodeficiency Virus (HIV) has become a treatable, chronic condition, but people with HIV still face an elevated risk of cardiovascular disease, including heart failure. Purpose To assess echocardiographic alterations in left ventricular (LV) function contemporary cohort well-treated compared to the general population. Methods We included 744 frequency matched 1:1 on age and sex controls from Both underwent echocardiography, physical examination, questionnaires...
Abstract Background Patients undergoing coronary artery bypass grafting (CABG) surgery face an elevated long-term risk of ischemic stroke. Left atrial (LA) mechanics including LA strain are known to predict both stroke and fibrillation in other populations. Evidence is conflicting with regards the clinical significance postoperative (POAF) its role association between unclear. Purpose The aim study was investigate reservoir patients CABG whether presence POAF modified this relationship....
Background Early recognition of cardiac dysfunction in patients with chronic obstructive pulmonary disease (COPD) may prevent future impairment and improve prognosis. Artificial intelligence (AI) using neural networks on Computed Tomographic (CT) imaging provides a measurement loss small vessel volume, as surrogate vascular injury, compensatory increase large volume. This study investigated alteration COPD its association structure function assessed by echocardiography. Methods: We studied...
Background: Evolvement in speckle-tracking echocardiography (STE) enable a detailed layer-specific analysis of the right ventricular (RV), which has shown to be promising way quantifying RV systolic function. We aimed evaluate usefulness free wall strain (RVFWS) for predicting cardiovascular outcome patients undergoing coronary artery bypass grafting (CABG). Methods: studied 317 scheduled CABG, with prior surgery. STE was performed acquire endocardial, midmyocardial, and epicardial RVFWS....