A5068536394- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Cardiovascular Function and Risk Factors
- Diabetes Management and Research
- Cardiac pacing and defibrillation studies
- Diabetes and associated disorders
- Diabetes Treatment and Management
- Pulmonary Hypertension Research and Treatments
- Acute Myocardial Infarction Research
- Cardiovascular Disease and Adiposity
- Pancreatic function and diabetes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Advanced X-ray and CT Imaging
- Metabolism, Diabetes, and Cancer
Gentofte Hospital
2020-2024
University of Copenhagen
2017-2024
Rigshospitalet
2017
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Despite improvement in treatment strategies of atrial fibrillation (AF), a considerable number patients still experience recurrence tachyarrhythmia (ATA) following catheter ablation (CA). This study aimed to investigate the prognostic value left (LA) deformation analysis large group undergoing CA for AF.This included 678 with AF. Echocardiography including two-dimensional speckle tracking echocardiography (2DSTE) was performed all prior CA. Logistic regression used assess association between...
Guidelines recommend prioritizing treatment with antiarrhythmic drugs before referral of patients atrial fibrillation to ablation, delaying a potential subsequent ablation. However, ablation may affect outcomes. We sought investigate the impact duration from diagnosis on risk recurrence and adverse events.
Posterior wall isolation (PWI) added to pulmonary vein (PVI) is increasingly used despite limited evidence of clinical benefit. We investigated the feasibility, durability, and efficacy index-procedure PVI + PWI radio frequency ablation (RFA) in patients with persistent atrial fibrillation (PeAF).Twenty-four PeAF participated prospective PeAF-Box study underwent RFA wide area circumferential ablation, roof- inferior lines achieve at index procedure. Follow-up included monitoring by an...
Abstract Background Pulsed field ablation (PFA) is a novel method of cardiac where there insufficient knowledge on the durability and reconnection patterns after pulmonary vein isolation (PVI). The aim this study was to characterize electrophysiological findings at time repeat procedure in real-world atrial fibrillation (AF) patients. Methods Patients who underwent ( n =26) for symptomatic recurrent arrhythmias index first-time treatment with single-shot PFA PVI =266) from July 2021 June...
Abstract Background Insulin-treated patients with type 2 diabetes (T2D) are at risk of hypoglycemia, which is associated an increased cardiovascular disease and mortality. Using a long-term monitoring approach, we investigated the association between episodes glycemic variability cardiac arrhythmias in real-life setting. Methods T2D (N = 21, [mean ± SD] age 66.8 9.6 years, BMI 30.1 4.5 kg/m , HbA1c 6.8 0.4% [51.0 4.8 mmol/mol]) were included for one-year observational study. Patients...
Reconnections to pulmonary vein (PV) triggers of atrial fibrillation (AF) are the primary cause AF recurrence after PV isolation (PVI) with radiofrequency (RF) or cryoballoon catheter ablation (CRYO), but method-specific contributions reconduction pattern and conductive gap location incompletely understood.The objective this versus for paroxysmal substudy was determine procedure-specific patterns in a randomized population protocol-mandated repeat procedures, irrespective recurrence. Each...
Abstract Aims Quantitative computed tomography (QCT) allows assessment of morphological features coronary atherosclerosis. We aimed to test the hypothesis that clinical patient presentation is associated with distinct Methods and results A total 1652 participants, representing a spectrum risk profiles [787 asymptomatic individuals from general population, 468 patients acute chest pain without syndrome (ACS), 397 ACS], underwent multidetector tomography. Of these, 274 individuals, 254 ACS,...
Pulmonary vascular abnormalities, quantified from computed tomography scans, have frequently been observed in patients with pulmonary diseases. However, little is known about changes cardiac disease. Thus, we aimed to examine the cardiopulmonary relation atrial fibrillation (AF) by comparing volume (PVV) echocardiographic measures and AF severity. A total of 742 (median age 63 years, 70% men) who underwent ablation for were included. Preprocedural was used measure small-vessel PVV, along...
BackgroundWe examined obstructive and nonobstructive plaque volumes in populations with subclinical clinically manifested coronary artery disease (CAD) using quantitative computed tomography (QCT).Methods855 participants CAD (274 asymptomatic individuals, 254 acute chest pain patients without syndrome (ACS), 327 ACS) underwent QCT of proximal segments to assess participant-level dense calcium, fibrous, fibrofatty, necrotic core tissue.ResultsNonobstructive (<50% stenosis) were greater than...
Abstract Introduction Atrial tachyarrhythmia recurrence during the blanking period (early ATA) after pulmonary vein isolation (PVI) is associated with an increased risk of later recurrence, but its relationship reconduction (PVR) poorly understood. The objective present study was to evaluate between early ATA and PVR. Second, provide data on optimal by (a) evaluating how predictive values for PVR are affected duration, (b) assessing temporal development in atrial fibrillation (AF) burden....
Insulin-treated patients with type 2 diabetes (T2D) are at risk of hypoglycemia, which is associated an increased cardiovascular disease. We investigated the association between episodes glycemic variability and cardiac arrhythmias in a real-life setting. T2D (N=21, [mean±SD] age 66.8±9.6 years, BMI 30.1±4.5 kg/m2, HbA1c 6.8±0.4% [51.0±4.8 mmol/mol]) were included for one-year observational study employing continuous glucose monitoring (118±6 days) implantable monitors (ICMs).The ICMs...
Background: Despite improvement in treatment strategies of atrial fibrillation (AF), a considerable number patients still experience recurrence tachyarrhythmia (ATA) following catheter ablation (CA). We hypothesized that baseline myocardial impairment the left atrium (LA) is useful identifying at high risk ATA recurrence. Methods: This retrospective study included 921 with AF who underwent CA. Echocardiography including two-dimensional speckle tracking echocardiography (2DSTE) was performed...