A5100780886- Cancer-related molecular mechanisms research
- Advanced Battery Materials and Technologies
- Advancements in Battery Materials
- Platelet Disorders and Treatments
- RNA modifications and cancer
- Advanced Battery Technologies Research
- Metallurgy and Material Forming
- Mechanical Engineering and Vibrations Research
- Fibroblast Growth Factor Research
- Legionella and Acanthamoeba research
- Peptidase Inhibition and Analysis
- HER2/EGFR in Cancer Research
- Urban Design and Spatial Analysis
- Protease and Inhibitor Mechanisms
- Vitamin C and Antioxidants Research
- Blood Coagulation and Thrombosis Mechanisms
- Engineering Structural Analysis Methods
- Structural Engineering and Vibration Analysis
- Bacterial Genetics and Biotechnology
- Cell Adhesion Molecules Research
- Proteoglycans and glycosaminoglycans research
- Advanced Breast Cancer Therapies
- Circular RNAs in diseases
- Cancer Treatment and Pharmacology
- Cultural Identity and Heritage
Xinjiang Medical University
2015-2024
Tumor Hospital of Xinjiang Medical University
2015-2024
Shanghai University
2022-2024
Fudan University
2017-2019
University of Kentucky
2010
China Academy of Building Research
2008
Collège de France
2006
Centre National de la Recherche Scientifique
2006
National University of Singapore
2005
Background Vitamin D binding protein-macrophage activating factor (DBP-maf) is a potent inhibitor of tumor growth. Its activity, however, has been attributed to indirect mechanisms such as boosting the immune response by macrophages and inhibiting blood vessel growth necessary for tumors. Methods Findings In this study we show first time that DBP-maf exhibits direct effect on prostate cells in absence macrophages. demonstrated inhibitory activity proliferation studies both LNCaP PC3 cancer...
This study aimed to analyze expression profiles of long noncoding RNAs (lncRNAs) in lung adenocarcinoma.lncRNA microarray technology was employed detect lncRNA 3 pairs adenocarcinoma tissues and adjacent tissues.We found 134 upregulated lncRNAs 460 downregulated compared tissues. Among them, LINC00152, LINC00691, LINC00578 showed the most significant changes upregulation, while LINC00668, LINC00710, LINC00607 downregulation. Fluorescent quantitative polymerase chain reaction (PCR) analysis...
A large number of long noncoding RNAs (lncRNAs) have been found to be implicated in varieties tumors. However, the contributions lncRNAs tumorigenesis renal clear cell carcinoma (RCCC) remain largely unknown. We performed a genome-wide analysis lncRNA expression RCCC and matched nontumor (NT) tissues identify new targets for further study carcinoma. The 3 NT were conducted using 4 × 180K Agilent Chips 6 selected validated by qRT-PCR 90 patients. differentially expressed mRNAs recognized...
Pseudomonas alcaligenes NCIMB 9867 (strain P25X) utilizes the gentisate pathway for degradation of aromatic hydrocarbons. The gene encoding alternative sigma (σ) factor σ54, rpoN, was cloned from strain P25X and a rpoN knock-out strain, designated G54, constructed by insertional inactivation with kanamycin resistance cassette. role σ54 in physiological response P. to induction assessed comparing global protein expression profiles wild-type mutant G54. Analysis two-dimensional polyacrylamide...
Tumor radiotherapy induces hematopoietic organ damage and reduces thrombocyte counts. Thrombocytopenia is a common disease. Some studies have shown that tRNA synthetase plays not only catalytic aminoacylation roles, but also functions similarly to cytokines. Recombinant human tyrosyl-tRNA with mutated Y341A (rhTyrRS (Y341A)) promotes megakaryocyte migrate from bone marrow peripheral blood. It would promote megakaryocytes in the lungs adhering vascular endothelial cells resulting platelet...
Garnet-type solid-state electrolytes (SSEs) show great potential because of high ionic conductivity and steadiness against metallic Li. However, the unstable property garnet in air poor interface contact with Li metal dramatically influence electrochemical performance. In this manuscript, TiO2 gel is coated on surface Li6.75La3Zr1.75Ta0.25O12 (LLZTO) pellets by a spin coating process, to remove impurity in-situ construct an air-stable lithiophilic LixTiyOz (LTO) layer electrolyte surface....
1052 Background: Following promising outcomes in hormone receptor (HR)-positive, HER2-negative endocrine-resistant advanced breast cancer (BC) with lerociclib plus fulvestrant, this study assesses the efficacy and safety of letrozole HR+/HER2- or metastatic BC. Methods: This randomized, double-blind, placebo-controlled phase III involved BC patients without prior systemic therapy for disease. Participants were allocated 1:1 to either (150mg twice daily) placebo letrozole. The primary...
Bioavailability of regulatory molecules such as growth factors or cytokines is tightly controlled in vivo. Measurement these circulation difficult, especially within the cell microenvironment, and static tissue culture studies, although valuable, cannot mimic conditions present blood vessels with regard to architecture flow dynamics. Using endothelial-lined synthetic capillaries, we measured capture fibroblast factor-2 (FGF-2) found that was critically dependent on rate presence heparan...
Lithium-rich layered oxide cathodes suffer from severe interfacial degradation, capacity attenuation and voltage fading which mainly result poor reversibility of anionic redox. In this study, a LiNbO3 integrated strategy including coating, spinel heterostructure Nb5+ doping has been proposed for stabilizing lattice oxygen improving structural stability. Among them, the coating layer can protect highly active peroxo-like electrolyte with three-dimensional (3D) lithium transport channels...
Le Taoji (Notes sur la céramique) est le plus ancien texte dont nous disposons Jingdezhen, métropole de céramique chinoise. Sa datation probablement l'une des questions qui ont divisé, depuis les années 1980, spécialistes Dans cet article, proposons revenir cette querelle érudite, d'abord pour émettre une nouvelle hypothèse du Taoji, place rédaction celui-ci à fin Song Sud, soit au milieu xme siècle, puis critiquer deux arguments lesquels se fondent auteurs datent Yuan, dominante remonte,...