- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- Clostridium difficile and Clostridium perfringens research
- Antibiotic Use and Resistance
- Escherichia coli research studies
- Coccidia and coccidiosis research
- Herpesvirus Infections and Treatments
- Pharmaceutical and Antibiotic Environmental Impacts
- thermodynamics and calorimetric analyses
- Diphtheria, Corynebacterium, and Tetanus
- Yersinia bacterium, plague, ectoparasites research
- Urological Disorders and Treatments
- Veterinary medicine and infectious diseases
- Rabies epidemiology and control
- Parasitic Infections and Diagnostics
- Streptococcal Infections and Treatments
- Viral gastroenteritis research and epidemiology
- Vibrio bacteria research studies
- Aquaculture disease management and microbiota
- Ichthyology and Marine Biology
- Reproductive Physiology in Livestock
- Bacillus and Francisella bacterial research
- Diverticular Disease and Complications
- Mycobacterium research and diagnosis
University of Liverpool
2019-2024
European Society of Clinical Microbiology and Infectious Diseases
2024
Biology of Infection
2022
are opportunistic pathogens with the potential to cause a variety of infections in both humans and animals many cases have developed antimicrobial resistance. In this study, we characterized extended-spectrum cephalosporin resistant (ESCR)
Antimicrobial stewardship guidelines (ASGs) represent an important tool to help veterinarians optimize their antimicrobial use with the objective of decreasing resistance. The aim this study was map and qualitatively assess ASGs for in cats dogs Europe. Country representatives European Network Optimization Veterinary Treatment (ENOVAT) were asked identify published countries. All collated updated since January 2010 containing recommendations on therapy at least three conditions affecting...
Healthcare-associated infections (HCAIs) associated with extended-spectrum cephalosporin-resistant gram-negative (ESC-R GN) bacteria are an emerging concern in veterinary hospitals, especially companion animal intensive care units (ICUs).To understand the molecular epidemiology of ESC-R GN isolates two hospitals (equine and small animal), a 6-month pilot study was performed during which fecal environmental samples were obtained twice from selected patients, upon ICU admission after 48 h...
Introduction The emergence of multi-drug resistant (MDR) pathogens linked to healthcare-associated infections (HCAIs) is an increasing concern in modern veterinary practice. Thus, rapid bacterial typing for real-time tracking MDR hospital dissemination still much needed inform best infection control practices a clinically relevant timeframe. To this end, the IR Biotyper using Fourier-Transform InfraRed (FTIR) spectroscopy has potential provide fast cluster analysis potentially related...
Faecal carriage of extended-spectrum cephalosporin-resistant (ESC-R) Enterobacterales in healthy pets is a concerning issue. This study aimed to determine the prevalence, genetic background, and potential for interspecies transmission these bacteria between dogs humans within same household (HH) or shelter environment Romania. samples (n = 263) collected from 102), their owners 32), as well 110) staff 19) dog shelters, were screened ESC-R carriage. Clonal relatedness canine human Escherichia...
Antimicrobial resistance is a public health concern. Understanding any role that urban seagulls may have as reservoir of resistant bacteria could be important for reducing transmission. This study investigated fecal Escherichia coli isolates from (herring gulls and lesser black-backed gulls) to determine the prevalence extended-spectrum cephalosporin-resistant (ESC-R) fluoroquinolone-resistant E. among gull species two cities (Taunton Birmingham) in United Kingdom (UK). We characterized...
Fluoroquinolones (FQ) are commonly used in dogs with bacterial skin infections. Their use as first choice, along the increased incidence of FQ-resistance, represents a risk to animal and public health. Our study determined minimum inhibitory (MIC) bactericidal (MBC) concentrations five FQs Staphylococcus aureus, pseudintermedius, Escherichia coli, together FQ-resistance mechanisms. MICs, efflux pump (EP) overexpression MBCs were measured 249 infection isolates following CLSI guidelines (CLSI...
Corynebacterium ulcerans (C. ulcerans) may cause diphtheria in humans and can be carried by a wide range of animal species including dairy cows and, more recently, dogs cats that have been increasingly involved zoonotic trasmission. We isolated characterized, WGS, toxigenic C. strain from diseased horse the United Kingdom showing clinical signs respiratory comparable to those seen people. Our results indicate role for horses as reservoirs ulcerans.
Elephant endotheliotropic herpesvirus hemorrhagic disease (EEHV-HD) is an acute, often fatal, multisystemic and one of the most significant causes mortality Asian elephants in captivity. Most fatal cases EEHV-HD are associated with EEHV1A EEHV1B juveniles. This case report describes clinical pathological features a co-infection Clostridium perfringens type C EEHV-HD, caused by EEHV4, adult female elephant. Although clostridial enterotoxemia has been occasionally reported elephants, this...
To purify Cryptosporidium spp. oocysts from clinical stool samples and evaluate using an up-to-date mass spectrometry protocol producing high-quality reference spectra.A refined purification was developed for stools, involving salt flotation potassium bromide density centrifugation. Purified were prepared matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF MS) by formic acid extraction, the extracts analysed Bruker MALDI Biotyper system. Individual spectral markers...
A retrospective study revealed ten cases of emphysematous ingluvitis in Loriinae birds from two zoological collections between 2009 and 2020. Common clinical features were sudden death with gas distention the crop, subcutaneous cervical emphysema poor body condition, but also included collapse, hypothermia abandonment. Macroscopic examination moderate crop enlargement, thickening minimal intraluminal content, to severe submucosal transmural gas-filled cysts (emphysema). Histopathology...
This case series describes the post-mortem findings in 17 bitches (Canis lupus familiaris) with a recent (<7 days) history of caesarean section, most (94%) which had undergone conservative section preservation uterus. Brachycephalic breeds accounted for 71% all cases, French Bulldog (35%, n = 6), English (18%, 3) and Boston Terrier (12%, 2) overrepresented. Eleven animals (65%) died between 4 48 h after surgery, whereas six (35%) during procedure. The common cause death was septicaemia (41%,...
Veterinary clinical microbiology laboratories play a key role in antimicrobial stewardship, surveillance of resistance and prevention healthcare associated-infections. However, there is shortage international harmonized guidelines covering all steps veterinary bacterial culture from sample receipt to reporting.
The authors are aware of no conflict interest. This research did not receive any specific grant from funding agencies in the public, commercial or not-for-profit sectors. is an original short communication. article has been published, and all approve its submission to designated journal, Journal Fish Diseases. data that support findings this study available corresponding author upon request.
The aim of this study was to assess the spread antimicrobial resistance (AMR) in sheep farms Greece and identify potential indicators improve field surveillance.Ninety-four samples milk, drinking water, animal feed, bedding, faeces were collected from 5 dairy farms.The processed for isolation Staphylococcus aureus Escherichia coli, assessment AMR using conventional microbiology polymerase chain reaction.Positivity coli 38.3% 16%, respectively (36 15 94).Detection feeds significantly higher...
Systemic nocardiosis due to Nocardia farcinica has not been reported in canine outbreaks. Two 14-week-old female Dogue de Bordeaux siblings presented with fever and severe, acute onset limb lameness; traumatic lesions evidence of infection were identified over the lame limbs both dogs. The patients euthanised owing lack therapeutic response rapid escalation systemic central nervous system manifestations. post-mortem changes consisted multiple disseminated abscesses, mainly affecting skin...