A5066851497- Veterinary Oncology Research
- Pediatric Hepatobiliary Diseases and Treatments
- Microbial Inactivation Methods
- Bacterial Identification and Susceptibility Testing
- Microbial infections and disease research
- Drug Transport and Resistance Mechanisms
- Liver Disease Diagnosis and Treatment
- Listeria monocytogenes in Food Safety
- Infectious Diseases and Mycology
- Essential Oils and Antimicrobial Activity
- Appendicitis Diagnosis and Management
- Multiple Sclerosis Research Studies
- Antibiotic Use and Resistance
- Oral microbiology and periodontitis research
- Electrolyte and hormonal disorders
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Abdominal vascular conditions and treatments
- Viral Infections and Vectors
- Polyomavirus and related diseases
- Congenital Ear and Nasal Anomalies
- Esophageal and GI Pathology
- Cerebrospinal fluid and hydrocephalus
- Escherichia coli research studies
- Inflammatory Bowel Disease
- Salmonella and Campylobacter epidemiology
University of Cambridge
2017-2025
Queen's Hospital
2018-2024
St Mark's Hospital
2000-2001
Abstract Two labrador retriever littermates presented separately to investigate chronic lethargy and shifting lameness. In both cases, clinical examination revealed a multi‐limb Neither the patients nor their dam or sire had travel history outside UK. Imaging of vertebral column in cases was consistent with discospondylitis. Brucella canis serology demonstrated rising antibody titre Case 1 strong positive 2 (4+/3200), diagnosis B. . Due concerns relating poor prognosis, antimicrobial...
Abstract Background Serum bile acids (SBAs) are frequently measured in dogs. However, there is limited data comparing SBAs different liver diseases diagnosed according to standardized histological criteria. Objectives To compare resting and postprandial SBAs, determine their sensitivity specificity, for various Animals Three hundred forty‐one client‐owned dogs with suspected disease that had a biopsy measured. Methods Multicenter retrospective study. Cases were classified The specificity of...
Antimicrobial stewardship initiatives are widely regarded as a cornerstone for ameliorating the global health impact of antimicrobial resistance. Within companion animal health, such efforts have largely focused on development and dissemination guidelines (ASGs). However, there been few attempts to understand veterinarian attitudes towards knowledge ASGs or determine how awareness regarding might best be increased. An online survey was formulated veterinarians who treat animals. The...
Objectives Serum amyloid A (SAA) concentrations are increased in cats with lymphoma vs healthy cats; however, the association between SAA and prognosis is unclear. The aim of this study was to evaluate if were different nasal non-nasal lymphoma, prognostic patients treated high-dose chemotherapy correlated other clinicopathological variables. Methods Cats diagnosed intermediate- or large-cell 2012 2022 concentration data available included. Associations tumour site (nasal non-nasal), stage,...
Abstract A 3‐year‐old male neutered domestic shorthair cat presented with lethargy, hyporexia, and pyrexia of unknown origin. Biochemical analysis using a Beckman Coulter AU480 demonstrated marked increases in creatine kinase aspartate aminotransferase, indicative severe muscle injury, concurrent presumptive myoglobinuria on urinalysis. marked, non‐physiologic increase measured bicarbonate resultant negative anion gap was documented; however, calculated obtained via point‐of‐care blood gas...
Veterinary clinical microbiology laboratories play a key role in antimicrobial stewardship, surveillance of resistance and prevention healthcare associated-infections. However, there is shortage international harmonized guidelines covering all steps veterinary bacterial culture from sample receipt to reporting.
Objectives To establish the utility of a novel in‐house method CSF analysis using sedimentation cytology direct from spinal needle for detection laboratory‐defined pleocytosis. Materials and Methods In dogs cats undergoing routine investigation neurological signs, an additional preparation was made at patient's side by inverting on slide sedimenting least 1 hour. Nucleated cellularity differential counts were assessed compared with “gold‐standard” analysis. Variability cell between observers...
A mediastinal mass was diagnosed in a 7-year-4-month-old neutered female mixed breed dog following 3-week history of lethargy, hyporexia and pyrexia. Bi-cavitary imaging, needle aspirate cytology flow cytometry confirmed WHO clinical stage IVb, intermediate to large T-cell lymphoma involving the mediastinum, liver spleen. The initially responded multidrug chemotherapy protocol but deterioration occurred 3 months later. presented with anorexia, vomiting diarrhoea, associated marked faecal...
An adult sulphur-crested cockatoo (Cacatua galerita) was unexpectedly found dead and presented for post-mortem examination. Macroscopically, the proventricular wall expanded by an infiltrative off-white mass, 10 mm in diameter, with secondary mucosal ulceration. Cytological examination of impression smears revealed a neoplastic epithelial cell population forming occasional well-defined acini secretory product. Histologically, cells were predominantly arranged tubules, fewer small clusters,...
veloped subsequent to the rhachitis.The latter was undoubtedly due improper food and surroundings, aud it seems more reasonable, in present state of our knowledge, consider leukemia as arising from same cause rather than secondary blood-count, made on April 26th, showed 2,900,000 red corpuscles 48,000 white per cubic millimetre, giving a proportion one sixty.A differential count 1,000 slips, dried staiued with Ehrlich's triple stain, resulted follows :Small lymphocytes. 234= 23.4 % Large...
A 3.6‐year‐old neutered female labrador retriever was presented with one month’s history of left hindlimb lameness and a five‐day anorexia. severe osteolytic osteoproductive polyostotic bone lesion affecting the proximal aspect tibia distal femur seen on radiographs. Histopathological evaluation confirmed cellulitis, myositis, neutrophilic osteomyelitis necrosis culture revealed pure growth β‐haemolytic Listeria species. To authors' knowledge this is first report caused by species in dog...
Abstract Background Salivary urea concentrations correlate with serum in dogs and humans. can now be determined semi‐quantitatively using a salivary test strip method that has been validated for use Objectives We aimed to evaluate the repeatability of score, correlation between scores dogs. Methods Intra‐run inter‐run variabilities were (n = 10 triplicate). Correlations assessed Spearman's coefficient. Receiver operator curve analysis was used diagnostic performance score identify...
A 3.6-year-old neutered female labrador retriever was presented with one month’s history of left hindlimb lameness and a five-day anorexia. severe osteolytic osteoproductive polyostotic bone lesion affecting the proximal aspect tibia distal femur seen on radiographs. Histopathological evaluation confirmed cellulitis, myositis, neutrophilic osteomyelitis necrosis culture revealed pure growth β-haemolytic Listeria species. To authors9 knowledge this is first report caused by species in dog...
A 1‐year, 8‐month‐old Rhodesian Ridgeback was presented with obtundation, ambulatory tetraparesis, and myoclonus. Initial clinical findings included ionized hypercalcemia an apparent marked increase in parathyroid hormone, thrombocytopenia, nonregenerative anemia. Low numbers of circulating atypical cells were noted on blood film evaluation. Brain magnetic resonance imaging identified extra‐axial contrast enhancing subtentorial lesion, cerebrospinal fluid (CSF) analysis documented a...
Abstract Currently, canine soft tissue sarcoma (STS) grading is based on histopathology. In humans, several studies have demonstrated concordance between cytologic systems for STS and histologic grade. The aim of this study was to correlate parameters (smear cellularity, anisokaryosis, nucleolar malignancy score, multinucleation, the number mitotic figures per 200 cells) that form part a human system, with grades cutaneous subcutaneous STS. Three observers (blinded) reviewed preparations...