A5072784690- Hepatitis C virus research
- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- Inflammation biomarkers and pathways
- Biosimilars and Bioanalytical Methods
- Tuberculosis Research and Epidemiology
- Hepatitis Viruses Studies and Epidemiology
- Immune Cell Function and Interaction
- Autoimmune and Inflammatory Disorders Research
- Inflammasome and immune disorders
- Sepsis Diagnosis and Treatment
- Immune Response and Inflammation
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Viral gastroenteritis research and epidemiology
Azienda Unità Sanitaria Locale di Ferrara
2024
Azienda Ospedaliera Santa Maria Degli Angeli
2015-2024
Ospedale Santa Maria
2021
To explore the relationship between innate immunity and hepatitis C Virus (HCV) in determining risk of cirrhosis (CIR), hepatocellular carcinoma (HCC), mixed cryoglobulinemia syndrome (MCS) non-Hodgkin lymphoma (NHL), we investigated impact toll-like receptor-2 (TLR2) interleukin-28B (IL28B) genetic variants. TLR2 -174 del variant was associated with expression specific downstream molecules that drive different interleukins; rs12979860 Il28B important response to interferon-treatment...
The expression of CD64 on neutrophils (nCD64), measured using flow cytometry, has been proposed as a biomarker for bloodstream infections (BSI). However, data regarding its use in the setting liver cirrhosis are lacking.
Adult-onset Still’s disease (AOSD) is a rare disease. Diagnosis of often difficult to achieve. Herein, we describe our diagnostic approach in case report regarding an adult patient who presented with fever, erythema, lymphadenopathy and arthralgia.
Acute hepatitis A is generally a self-limited disease in healthy subjects within few weeks, but an uncommon type of prolonged and biphasic acute course infection has been also described. This presentation observed about 6-10% patients, small number reports, concerning this topic, are available literature. In addition virus (HAV) B (HBV) carriers rarely discussed. 41-year-old Italian man, already known to our Department for HBV as inactive carrier HBsAg(+)ve, experienced A, lasting 7 months....
Hepatitis C virus (HCV)-related chronic hepatitis is characterized by different clinical outcomes as well distinct biochemical and virological patterns. According to guidelines concerning dual therapy, high rates of sustained response (or HCV-RNA undetectable 24 weeks after the end antiviral treatment) has been obtained in patients with persistent HCV infection, caused genotype 2 (CHC G2). Dual therapy (pegylated interferon plus ribavirin) might be an useful strategy not only treatment...
Data about co-infection of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2), HIV, and hepatitis C virus (HCV) are still scarce. We describe a patient hospitalized for sore throat, fatigue, myalgia with personal history HIV occult HBV infection. His antiretroviral therapy included bictegravir/emtricitabine/tenofovir alafenamide. The nasopharyngeal swab was positive SARS-CoV-2 laboratory testing showed HCV. Antiretroviral continued, but no specific started. After 4 weeks,...