A5072746457- Immunotherapy and Immune Responses
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- Advanced Photocatalysis Techniques
- Topic Modeling
- Cancer Immunotherapy and Biomarkers
- Luminescence and Fluorescent Materials
- Wnt/β-catenin signaling in development and cancer
- Speech and dialogue systems
- Advanced biosensing and bioanalysis techniques
- Quantum Dots Synthesis And Properties
- Advanced X-ray and CT Imaging
- Advanced Text Analysis Techniques
- Proteoglycans and glycosaminoglycans research
- Intracerebral and Subarachnoid Hemorrhage Research
- Pigment Synthesis and Properties
- Tuberous Sclerosis Complex Research
- Geotechnical Engineering and Soil Stabilization
- Celiac Disease Research and Management
- Kruppel-like factors research
- Global Financial Regulation and Crises
- Genomics and Chromatin Dynamics
- Fiber-reinforced polymer composites
- Intelligent Tutoring Systems and Adaptive Learning
- Radioactive Decay and Measurement Techniques
Chinese Academy of Medical Sciences & Peking Union Medical College
2017-2025
Chuzhou University
2023-2025
Anhui Medical University
2023-2025
Changchun Institute of Technology
2024-2025
Beijing Institute of Technology
2024
Tongji University
2023
Xuzhou Central Hospital
2023
Yuhuangding Hospital
2023
Tongji Hospital
2023
Chongqing University of Technology
2023
Hepatic epithelioid angiomyolipoma is a rare mesenchymal liver tumor within the perivascular cell family, known for its uncertain malignancy and potential aggressive behavior. Clinical presentation, laboratory findings, imaging results lack specificity, making pathological examination critical definitive diagnosis. This case report presents 61-year-old male patient with single in right lobe, measuring approximately 101 mm × 99 mm. Initial misdiagnosed mass as hepatocellular carcinoma....
Abstract T-cell receptor (TCR) γδ-expressing cells are conserved lymphocytes of innate immunity involved in first-line defense and immune surveillance. TCRγδ recognizes protein/nonprotein ligands without the help major histocompatibility complex (MHC), especially via direct binding to protein ligands, which is dependent primarily on δ chain complementary determining region 3 (CDR3δ). However, mechanism protein‒antigen recognition by human γδ TCRs remains poorly defined. We hypothesize that...
Abstract The cohesin complex participates in the organization of 3D genome through generating and maintaining DNA loops. Stromal antigen 2 (STAG2), a core subunit complex, is frequently mutated various cancers. However, impact STAG2 inactivation on organization, especially long-range enhancer-promoter contacts subsequent gene expression control cancer, remains poorly understood. Here we show that depletion melanoma cells leads to expansion topologically associating domains (TADs) enhances...
Background: Cerebral aneurysms (CAs) are a significant cerebrovascular ailment with multifaceted etiology influenced by various factors including heredity and environment. This study aimed to explore the possible link between different types of immune cells occurrence CAs. Methods: We analyzed connection 731 cell signatures risk CAs using publicly available genetic data. The analysis included four features, specifically median brightness levels (MBL), proportionate (PC), definite (DC),...
The compressive bearing capacity of a new type concrete-expanded plate pile (NT-CEP pile) is significantly affected by the size platform; however, research in this area remains limited. Therefore, study investigates effect platform on an NT-CEP foundation under combined vertical and horizontal loads. Using ANSYS finite element software, four-pile model was established to analyze failure behavior surrounding soil these findings indicate that foundation, piles with increased 66.67% compared...
Abstract Most nonalcoholic steatohepatitis (NASH) patients develop severe fibrosis through extracellular matrix (ECM) accumulation, which can lead to hepatocellular carcinoma (HCC). Fibroblast growth factor 9 (FGF9) is involved in serial types of cancer; however, the specific role FGF9 NASH‐driven HCC not fully understood. This study finds that increased with NASH‐associated HCC. Furthermore, mice models by feeding wildtype high‐fat/high‐cholesterol (HFHC) diet and low dose carbon...
The slow light effect at the band gap edge of photonic nanocrystals (PhCs) can improve utilization efficiency photocatalysts by enhancing collection. This study reported an anatase inverse opal TiO2 (IO TiO2) with a 3D closely packed face-centered cubic structure prepared using PhC template. simulation electric field modulus distribution in was performed, and enhancement photocatalytic caused red blue edges analyzed. experimental results rhodamine B degradation agreed simulation. IO has high...
The rapid expansion of the scale wind power has led to a wave efforts decommission turbine blades. pyrolysis decommissioned blades (DWTBs) is promising technological solution. Microwave offers benefits fast heating rates and uniform heat transfer, making it widely used method in various applications. However, there are few studies on microwave DWTBs, characteristics under different boundary conditions remain unclear. In this paper, we investigate DWTBs by utilizing silicon carbide (SiC)...
Pile spacing is an important factor affecting the bearing capacity of concrete expansion pile (CEP) groups. In this study, a group was simulated and analyzed using ANSYS software R19.0. The influence on under vertical load determined three sets four-, six-, nine-pile models with different spacings. grid division soil model adopts mapping method, contact types rigid flexible bodies applying surface loads to piles step-by-step. After pressure applied pile, in-depth analysis conducted...
Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) infection is a serious threat to human health. γδT cells, which are characterized major histocompatibility complex (MHC) nonrestriction, rapidly activated and initiate anti-infectious immune responses in the early stages of Mtb infection. However, mechanism underlying recognition cells remains unclear. In this study, we pattern T-cell receptor (TCR) γδ complementary determinant region 3 (CDR3) repertoire TB patients using...
Surgery, chemotherapy, and radiotherapy have presented with the ability of killing tumor cells, as well damaging immune function, which can be corrected by immunotherapy. The purpose this perspective cohort study was to evaluate efficacy postoperative immunotherapies lysate-loaded dendritic cells (DC), in vitro DC-activated T (DC-AT), activated (ATC) combined chemotherapy on survival patients operable colorectal cancer. A total 253 primary cancer resection including 181patients receiving...
Dialogue State Tracking is an essential component in multi-domain dialogue systems, aiming to accurately determine the current state based on history. Existing research has addressed issue of multiple mappings dialogues by employing slot self-attention as a data-driven approach. However, learning relationships between slots from single sample limitations and introduces noise. In this paper, we propose External Slot Relation Memory-based model (ER-DST). By utilizing external memory storage,...
BACKGROUND The aim of this study was to investigate the effect antigenic peptides on dendritic cell maturation and activation as well role induced function. tumor-specific cytotoxic T lymphocytes by cells were also evaluated. MATERIAL AND METHODS SW-480 lysate peptide antigens selected adjuvants in sensitization, tuftsin used induce phagocytosis cells. Immature stimulated with antigen adjuvant follows: group A negative control; B (20 μg/mL); C μg/mL)+tumor necrosis factor (TNF)-alpha (10 D...
In response to growing concerns about public safety and environmental conservation, it is essential develop a precise identification method for trace explosives. To improve the stability detection sensitivity of perovskite quantum dots (PQDs) address issue low porosity in traditional polymer-based photonic crystals (PhCs), this study proposed PQD photoluminescence (PL) enhancement strategy based on slow light effect ZIF-8 PhCs highly sensitive, selective, convenient 2,4,6-trinitrophenol...
Background Lewis rat is a commonly used specie in experimental autoimmune uveitis(EAU).However,the characteristics of EAU,especially ocular uhrastructural change,are rarely reported.Objective This study was to investigate the inflammatory and uhrastructure EAU models rat.Methods were induced 12 SPF female rats(6-8 weeks old)by injection complete Freund adjuvant(CFA) containing interphotoreceptor retinoid-binding protein (IRBP,1177-1191) tuberculin (TB) into footpads,napes back body,and 6...
Abstract Introduction Some beneficial effects of cheese intake on disease have been reported in several observational studies, However, there is still a gap the study infectious diseases. We aimed to apply two-sample Mendelian randomization (MR) approach assess causal relationship between and Methods used analyze relevant data from publicly available genome-wide association studies infer causality. The random-effects inverse-variance-weighted method was calculate effect estimates. Results...
Dialogue state tracking is an essential component in multi-domain dialogue systems that aims to accurately determine the current based on history. Existing research has addressed issue of multiple mappings dialogues by employing slot self-attention as a data-driven approach. However, learning relationships between slots from single sample often limitations and may introduce noise have high time complexity issues. In this paper, we propose external relation memory-based model (ER-DST). By...