A5100445275- Pregnancy and preeclampsia studies
- Congenital Heart Disease Studies
- Prenatal Screening and Diagnostics
- Congenital Diaphragmatic Hernia Studies
- Fetal and Pediatric Neurological Disorders
- Birth, Development, and Health
- Tracheal and airway disorders
- Parvovirus B19 Infection Studies
- Heme Oxygenase-1 and Carbon Monoxide
- Congenital Anomalies and Fetal Surgery
- Paraquat toxicity studies and treatments
- Gestational Diabetes Research and Management
- Reproductive Biology and Fertility
- Assisted Reproductive Technology and Twin Pregnancy
- Cardiovascular Issues in Pregnancy
- Endometrial and Cervical Cancer Treatments
- Congenital heart defects research
- Urological Disorders and Treatments
- Plant-derived Lignans Synthesis and Bioactivity
- Maternal and Perinatal Health Interventions
- Liver Disease Diagnosis and Treatment
- Biological Activity of Diterpenoids and Biflavonoids
- Ureteral procedures and complications
- Gynecological conditions and treatments
- Pediatric Hepatobiliary Diseases and Treatments
China Medical University
2015-2025
Shanghai First Maternity and Infant Hospital
2024
Hubei University of Chinese Medicine
2024
Hubei University of Medicine
2020-2023
Tongji University
2023
Taihe Hospital
2023
Affiliated Hospital of Southwest Medical University
2021-2022
Jiangxi Pingxiang People's Hospital
2022
Peking University First Hospital
2022
Peking University
2005-2022
Abstract Background Improving quality of life (QoL) has been one the goals health care for people living with oral cancer. This study aimed to assess QoL and investigate effects stigma, hope, social support on among Chinese cancer patients. Methods A cross-sectional was conducted at Department Stomatology, Shengjing Hospital China Medical University Stomatology in Liaoning Province, China, between May 2016 October 2017. total 230 patients were recruited complete a questionnaire including...
Biliary atresia (BA) is a rare and severe congenital disorder with significant challenge for prenatal diagnosis. This study, registered at the Chinese Clinical Trial Registry (ChiCTR2200059705), aimed to develop an intelligent model aid in diagnosis of BA. To evaluate this model, fetuses from 20 hospitals across China infants sourced public database were collected. The transfer-learning (TLM) demonstrated superior diagnostic performance compared basic deep-learning higher area under curves...
Congenital malformations are common birth defects with high neonatal morbidity and mortality. It is essential to find simpler more efficient biomarkers for early prenatal diagnosis. Therefore, we investigated PIWI-interacting RNAs (piRNAs) as potential in plasma-derived exosomes from pregnant women carrying foetuses congenital malformations.Small RNA sequencing was used screen piRNA of five nonsyndromic cleft lip palate (nsCLP) normal foetuses. Differentially expressed piRNAs were verified...
Abstract Background Due to metabolic changes in the second trimester and increasing number of pregnant women with obesity advanced maternal age, incidence gestational diabetes mellitus (GDM) remains high. This study aimed evaluate effects GDM on fetal cardiac morphology function, determine whether these increase estimated weight (EFW). Methods Fifty-eight (GDM group) 58 a healthy pregnancy (control were included this prospective observational cohort study. Each group subgroups 31 age between...
Though social anxiety and recognition have been studied extensively, the roles of medial or basolateral amygdala in control remain to be determined. This study investigated effects excitotoxic bilateral lesions upon in-mice.Animals at 9 weeks age were given via infusion N-methyl- D-aspartate then used for behavioral tests: anxiety-related tests (including open-field test, light-dark elevated-plus maze test), behavior test a novel environment, flavor test.Medial amygdala-lesioned mice showed...
Paraquat, a widely used herbicide, is well known to exhibit oxidative stress and lung injury. In the present study, we investigated possible underlying mechanisms of cannabinoid receptor-2 (CB2) activation ameliorate proinflammatory activity induced by PQ in rats. JWH133, CB2 agonist, was administered intraperitoneal injection 1 h prior exposure. After exposure for 4, 8, 24, 72 h, bronchoalveolar lavage fluid collected determine levels TNF-α IL-1β, arterial blood samples were detection PaO2...
Obtaining an accurate diagnosis of fetal aortic arch anomalies is often difficult with traditional two-dimensional (2D) sonography. Thus, the aim this study was to assess value three-dimensional (3D) sonography spatiotemporal image correlation for diagnosing using a novel algorithm 3D volume analysis.Two-dimensional and echocardiographic data from 300 normal fetuses 30 were retrospectively reviewed. Grayscale high-definition flow imaging available 2D echocardiography. Three-dimensional...
Di-(2-Ethylhexyl) phthalate (DEHP) and bisphenol A (BPA) present significant environmental endocrine-disrupting chemical properties. Although studies have implied reproductive impairment from exposure to BPA DEHP, no study date has shown the effect mechanism of hepatic function after gestational lactational co-exposure DEHP in offspring. total 36 perinatal rats were randomly divided into four groups, (600 mg/kg/day), (80 combined with mg/kg/day + 80 control. Notably, 11 targets screened...
Two new β-bergamotane sesquiterpenoids, E-β-trans-5,8,11-trihydroxybergamot-9-ene (1) and β-trans-2β,5,15-trihydroxybergamot-10-ene (2), were isolated from the marine-derived fungus Aspergillus fumigatus YK-7, along with three known terpenoids 3–5. Their structures determined by spectroscopic methods (1D 2D NMR, HR-ESI-MS). Antiproliferative effects on human leukemic monocyte lymphoma U937 prostate cancer PC-3 cell lines measured in vitro. Compound 4 exhibited potent activity against line an...
Capsaicin (CAP) exerts significant anti-tumor effects on a variety of tumors, with low intrinsic toxicity.Cisplatin (DDP) is currently the first-line drug for treatment oral cancer; however, its clinical efficacy impeded by chemoresistance and negligible side effects.Whether combined use CAP DDP has synergistic antitumor effect tongue squamous cell carcinoma (TSCC) cells underlying mechanisms remains unclear.The present study revealed that reduced activity TSCC in dose-and time-dependent...
To build and evaluate a radiomics-based nomogram that improves the predictive performance of LVSI in cervical cancer non-invasively before operation.
The accurate prediction of the status PLNM preoperatively plays a key role in treatment strategy decisions early-stage cervical cancer. aim this study was to develop and validate radiomics-based nomogram for preoperative pelvic lymph node metastatic One hundred fifty patients were enrolled study. Radiomics features extracted from T2-weighted MRI imaging (T2WI). Based on selected features, support vector machine (SVM) algorithm used build radiomics signature. developed incorporating signature...
Abstract Background It is challenging to predict the outcome of pregnancy when fetal heart activity detected in early pregnancy. However, an accurate prediction importance for obstetricians as it helps provide appropriate consultancy and determine frequency ultrasound examinations. The purpose this study was investigate role convolutional neural network (CNN) spontaneous miscarriage risk through analysis gestational sac images. Methods A total 2196 images from 1098 women with singleton...
Fetal unilateral lung agenesis, complicated with cardiac shifting, is a rare anomaly, the diagnosis of which remains challenge for many sonographers in routine screening programs. The present study describes systematic approach fetal agenesis and malpositions prenatal screening. A total 18 cases malposition were reviewed. method was proposed to identify left side right according head position posture by acquiring long axis transverse view fetus. diagnosed evaluation ipsilateral pulmonary...
Acute pancreatitis in pregnancy (APIP) is a rare but dangerous complication. APIP has common symptoms with acute abdomen. Assessment of an abdomen more complicated during because the gravid uterus could mask most symptomatic signs. It been challenge to diagnose by physical examination or diagnostic imaging. Case studies on are also limited for analysis risk factors associated disease. This retrospective study evaluated series from relatively substantial number cases determine early...