A5090828799- Autoimmune Bullous Skin Diseases
- Immunodeficiency and Autoimmune Disorders
- Fungal Infections and Studies
- Dermatology and Skin Diseases
- Hair Growth and Disorders
- Antifungal resistance and susceptibility
- Traumatic Brain Injury and Neurovascular Disturbances
- Contact Dermatitis and Allergies
- Nail Diseases and Treatments
- Drug-Induced Adverse Reactions
- Infectious Diseases and Mycology
- Dye analysis and toxicity
- Tumors and Oncological Cases
- Plant Pathogens and Fungal Diseases
- Viral Infections and Vectors
- Leprosy Research and Treatment
- Research on Leishmaniasis Studies
- Body Image and Dysmorphia Studies
- Genetic and rare skin diseases.
- Syphilis Diagnosis and Treatment
- Bartonella species infections research
- Nonmelanoma Skin Cancer Studies
- Trace Elements in Health
- Neonatal skin health care
- Spondyloarthritis Studies and Treatments
CUF Porto Hospital
2024
Centro Hospitalar do Porto
2018-2023
Hospital de Santo António
2023
CD4+ T cells are vital for host defense and immune regulation. However, the fundamental role of CD4 itself remains enigmatic. We report seven patients aged 5–61 years from five families four ancestries with autosomal recessive deficiency a range infections, including recalcitrant warts Whipple’s disease. All homozygous rare deleterious variants impacting expression canonical isoform. A shorter expressed isoform that interacts LCK, but not HLA class II, is affected by only one variant. lack...
Abstract Uncombable hair syndrome is a rare disorder of the shaft that leads to silvery and unruly hair. The anomaly characterized by longitudinal groove detected scanning electronic microscopy—considered be gold standard for diagnosis. Recently, cross‐sectioning has been reported as viable alternative, but currently available methods still have some flaws, especially because samples' processing specificities. Here, we present two cases uncombable new embedding technique using epoxy perform
Abstract CARD14‐associated papulosquamous eruption (CAPE) is a rare inflammatory skin that can have features of psoriasis, pityriasis rubra pilaris, and erythroderma. This condition known for its resistance to topical or conventional systemic therapies. Successful treatment CAPE with anti‐IL‐12/IL‐23 IL‐17 inhibitors has been reported. We present case 2‐year‐old girl who was successfully treated ustekinumab.
Dermatophytes are common keratinophilic fungi responsible for superficial skin infections. Deep dermatophytosis is a rare form of invasive infection described in immunocompromised patients. We report the case 65-year-old man with history an orthotopic liver transplant hepatocarcinoma 6 months earlier, who presented small painless erythematous papules lower limbs, some which were umbilicated. Skin biopsy showed intense non-necrotizing granulomatous reaction dermis around fungal structures....
A Síndrome da Imunodeficiência Adquirida (Sida/Aids) é causada pelo vírus HIV. transmissão vertical, responsável por 90% dos casos de Aids em menores 13 anos no Brasil. OBJETIVO: Descrever o perfil farmacoterapêutico gestantes HIV positivo atendidas Hospital Universitário Materno Infantil, Maranhão, período janeiro 2019 a dezembro 2020 e avaliar se as medidas profilaxia esquema terapêutico foram efetivos para os recém-nascidos através do rastreamento positivo. METODOLOGIA: Trata-se um estudo...
The UK National Student Survey (NSS) is a sound and widely used instrument for assessing students’ academic experiences. We aimed to translate the NSS Portuguese students validate in sample of medical undergraduates. research team translated adapted (NSS-P). survey was administered on an online platform 1,256 final-year at eight schools. A total 329 (69.9% female) replied NSS-P, response rate 26.2%. Confirmatory factor analysis showed that original six-factor structure had adequate fit data....
We report a case of perianal reactivation herpes simplex virus type 2 in 27-year-old man, who was HIV positive with good immunovirological status, after laser-assisted (alexandrite) hair removal session. discuss the clinical and laboratory features role prophylaxis antivirals, particularly certain patients such as immunocompromised ones.
The diagnosis of secondary syphilis can be challenging for clinicians due to its diversified cutaneous presentations.This is particularly true human immunodeficiency virus (HIV) coinfected patients, who may develop unusual clinical manifestations.We report a case 33-year-old male, with HIV-1 infection without treatment, presented the emergency department (ED) 3-month history erythematous macules.In week before presenting ED, lesions had progressed multiple generalized papulovesicles and...
Species associated with visceral leishmaniasis, such as L. infantum, may be responsible for cutaneous leishmaniasis (CL), particularly in the Mediterranean region. In immunosuppressed hosts, classification complicated CL is essential, risk of mucosal warrants systemic therapy. We report case a forty-seven-year-old male living Portugal, Fabry disease and receiving immunosuppressive treatment adalimumab methotrexate Crohn’s disease. There was no travel history outside Europe. He presented...
Allergic contact dermatitis (ACD) is a type IV, delayed-type reaction caused by skin with low-molecular-weight organic chemicals and metal ions that activate antigen-specific T cells, primarily T-helper 1 (Th1), in sensitized individual, leading to eczema.First-line treatments are based on avoidance of causal agents topical corticosteroids/immunomodulators. In recalcitrant cases, chronic oral immunosuppressive may be used, but they have serious adverse effects do not address the...
A 51-year-old woman, clinically diagnosed with Xeroderma pigmentosum (XP), showed abnormalities in liver enzymes, high ferritin and transferrin saturation levels, ultrasonographic features of chronic disease, addition to skin hyperpigmentation. Genetic testing confirmed the clinical hypothesis hereditary hemochromatosis (HH). Due known proximity HFE (6p22.2) POLH (6p21.1) genes, accountable for HH XP-V variant, respectively, a genetic test was offered rare variant gene identified. We report...
.

 Cutaneous squamous cell carcinoma in situ of the eyelid and periorbital skin malignancies is common its management demanding. Surgical excision considered first-line treatment, but these techniques have limitations. Topical photodynamic therapy currently approved for treatment other areas, reports use this sensitive anatomic location area are scarce. Herein we report case a 61-year-old-man with extensive periocular Bowen disease that was treated successfully therapy. Photodynamic may...