A5005052446- Breast Cancer Treatment Studies
- Nanoplatforms for cancer theranostics
- Advanced Measurement and Detection Methods
- Cancer Immunotherapy and Biomarkers
- Radiomics and Machine Learning in Medical Imaging
- AI in cancer detection
- Image Retrieval and Classification Techniques
- Image and Video Stabilization
- Osteoarthritis Treatment and Mechanisms
- Bone Metabolism and Diseases
- Remote Sensing and Land Use
- Medical and Biological Ozone Research
- Cancer Treatment and Pharmacology
- Pharmacological Effects of Medicinal Plants
- Advanced Computational Techniques and Applications
- Advanced Measurement and Metrology Techniques
- Solar Radiation and Photovoltaics
- Advanced Breast Cancer Therapies
- Autophagy in Disease and Therapy
- Advanced Decision-Making Techniques
- Sensorless Control of Electric Motors
- Iterative Learning Control Systems
- Congenital heart defects research
- Energy Load and Power Forecasting
- BRCA gene mutations in cancer
Sichuan University
2017-2025
Guiyang Medical University
2024
State Key Laboratory of Biotherapy
2022-2023
China Southern Power Grid (China)
2023
Lanzhou Jiaotong University
2021
Institute of Electrical Engineering
2019
Chinese Academy of Sciences
2019
Sichuan Cancer Hospital
2017
Shenyang Aerospace University
2007-2016
Dalian University of Technology
2014
Abstract Human epidermal growth factor receptor 2 (HER2)-positive breast cancer (BC) has been the most challenging subtype of BC, consisting 20% BC with an apparent correlation poor prognosis. Despite that pyrotinib, a new HER2 inhibitor, led to dramatic improvements in prognosis, efficacy pyrotinib monotherapy remains largely restricted due its acquired resistance. Therefore, identifying potential antitumor drug combination amplify therapeutic is pressing necessity. Here, we reported novel...
Little is known about whether age at initial diagnosis influences the prognosis of recurrent metastatic breast cancer (rMBC). Here, we analyzed association between and rMBC mortality in China.A total 1636 women diagnosed with 1989 2020 West China Hospital, Sichuan University were included this study. The was categorized as young (≤ 40 years), middle-aged (41-64 years) elderly (≥ 65 years). Post-metastasis primary outcome its associated factors by Cox proportional hazards models.During a...
Abstract Background With the largest sample size to date, authors’ objective was investigate incidence of primary‐to‐metastatic human epidermal growth factor 2 (HER2) conversion and predictors for such conversion. Moreover, no previous studies have evaluated prognosis patients who negative HER2 expression (HER2‐0) versus low (HER2‐low) when status assessed based on all recurrent/metastatic lesions. Methods The authors included 1299 had available primary breast tumors paired lesions at Fudan...
Despite revolutionary achievements have been made in clinical cancer therapy, the immune checkpoint blockade regimen still presents limited efficacy on tumors lack of neoantigens exposure. Here, we designed and synthesized an on-demand microwave-controlled ozone release nanosystem to specifically generate reactive oxygen species tumor mass. By taking advantage iRGD modification, can be enriched microenvironment subsequently internalized by cells. Triggered low-power microwave, was released...
Osteoarthritis (OA) is a chronic degenerative disease mainly characterized by cartilage damage and synovial inflammation. Si Miao Powder, an herbal formula, was recorded in ancient Chinese medicine prescription with excellent anti-inflammatory properties. Based on the classical modified Powder (MSMP) developed addition of two commonly orthopedic herbs, which had efficacy strengthening therapeutic effect for OA.
The paper proposes an improved gradient algorithm which is based on the existing sobel edge detection.The not only simple, but also can solve coordination problem between detection precision and anti-noise performance.Experimental results prove that using modified to detect image clear outline, good real-time, has better performance.
Current online prognostic prediction models for breast cancer, such as Adjuvant! Online and PREDICT, are based on specific populations. They have been well validated widely used in the United States Western Europe; however, several validation attempts non-European countries revealed suboptimal predictions.We aimed to develop an advanced cancer prognosis model disease progression, cancer-specific mortality, all-cause mortality by integrating tumor, demographic, treatment characteristics from...
// Dan Zheng 1, 2, * , Hua-Ping Mou 3, Peng Diao 4, Xiao-Ming Li 5 Chuan-Li Zhang 3 Jing Jiang Jia-Lian Chen Li-Shuai Wang 6 Qiu Guang-Yuan Zhou Jie Chuan Lin and Zhi-Ping Yuan 5, 1 Department of Head Neck Mammary Gland Oncology, Medical Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, P.R. 2 State Key Laboratory Biotherapy/Collaborative Innovation Center Biotherapy, The Gynecology, Second People's Hospital Province, Yibin City, Yibin, 644000, 4 Institute,...
Triple-negative breast cancer (TNBC) is a type of highly invasive with poor prognosis. Recently, massive data reveal that long non-coding RNAs (lncRNAs) play important roles in progress. although the role lncRNAs has been well documented, few focused on TNBC. In this study, we aimed to systematically identify functional and explore its molecular mechanism TNBC
This study examines the influence of ligands with different N-substitution modes and heavy atom effects on transition metal complexes.
Abstract Background Despite the proportion of elderly breast cancer patients has been consistently increasing, optimal treatment modalities for this population have not well explored. We summarized outcomes these in our hospital. Methods Older with early were identified from Breast Cancer Information Management System at West China Hospital, Sichuan University (2000–2019). compared tumor characteristics and between older group (65–74 years old) (≥75 old). The Kaplan-Meier Cox regression...
The paper proposes an improved gradient algorithm which is based on the existing sobel edge detection. not only simple, but also can solve coordination problem between detection precision and anti-noise performance. Experimental results prove that using modified to detect image clear outline, good real-time, has better
Abstract In the research of solar power prediction, providing accurate prediction data in real time is one most effective means to enhance capacity wind acceptance and improve reliability economy. The existing models based on statistical methods are often unavoidable preprocessing model training stage, their adaptive ability needs be improved. Considering that sparse coding method does not require training, has characteristics high solving efficiency strong self-adaptability, an online...
A high power density inverter, the size of control board also plays an important role. Designing a small, full-featured, high-performance and reliable main is extremely in high-power permanent magnet synchronous motor inverter. The hardware platform simple design but excellent performance. 85mm long 60mm wide, all chips are 125 degrees working temperature. has experiment on 83kW controller. results show that performance good reliability.