A5022514053- Family Support in Illness
- Endometriosis Research and Treatment
- Cancer survivorship and care
- Boron Compounds in Chemistry
- Palliative Care and End-of-Life Issues
- Menstrual Health and Disorders
- Maternal Mental Health During Pregnancy and Postpartum
- Uterine Myomas and Treatments
- Birth, Development, and Health
- Radiopharmaceutical Chemistry and Applications
- Multiple and Secondary Primary Cancers
- Cancer, Stress, Anesthesia, and Immune Response
- Childhood Cancer Survivors' Quality of Life
- Health and Wellbeing Research
- Global Cancer Incidence and Screening
- Migration, Health and Trauma
- Cervical Cancer and HPV Research
- RNA Interference and Gene Delivery
- Genetic Associations and Epidemiology
- Pregnancy and preeclampsia studies
- Breast Cancer Treatment Studies
- Grief, Bereavement, and Mental Health
- Child Abuse and Trauma
- Cancer Risks and Factors
- Endometrial and Cervical Cancer Treatments
Karolinska Institutet
2016-2025
West China Medical Center of Sichuan University
2018-2024
The University of Sydney
2023-2024
Harvard University
2019-2024
Henan Provincial Center for Disease Control and Prevention
2024
Sichuan University
2013-2023
West China Hospital of Sichuan University
2009-2023
Zhejiang Gongshang University
2023
Harvard University Press
2023
Stockholm South General Hospital
2023
Abstract Background Due to the drastic surge of COVID-19 patients, many countries are considering or already graduating health professional students early aid resources. We aimed assess outbreak-related psychological distress and symptoms acute stress reaction (ASR) in characterize individuals with potential need for interventions. Methods conducted a prospective cohort study 1442 at Sichuan University, China. At baseline (October 2019), participants were assessed childhood adversity,...
Psychiatric comorbidities are common among patients with cancer. However, whether or not there is increased risk of mental disorders during the diagnostic workup leading to a cancer diagnosis was unknown.To examine relative risks depression, anxiety, substance abuse, somatoform/conversion disorder, and stress reaction/adjustment disorder periods before after compared individuals without cancer.Nationwide matched cohort study from January 1, 2001, December 31, 2010, in Swedish population...
Exposure to adverse childhood experiences (ACEs) has consistently been associated with multiple negative mental health outcomes extending into adulthood. However, given that ACEs and psychiatric disorders cluster within families, it remains be comprehensively assessed what extent familial confounding contributes associations between clinically confirmed adult disorders.
To determine whether women with perinatal depression are at an increased risk of death compared who did not develop the disorder, and full sisters.
Suicidal ideation is common among women with perinatal depression (PND). However, prospective data are limited on the risk, particularly long-term of suicidal behavior (suicide attempt and completed suicide) depression.
On April 29, 2014, the FDA granted accelerated approval to ceritinib (ZYKADIA; Novartis Pharmaceuticals Corporation), a breakthrough therapy-designated drug, for treatment of patients with anaplastic lymphoma kinase (ALK)-positive, metastatic non-small cell lung cancer (NSCLC) who have progressed on or are intolerant crizotinib. The was based single-arm multicenter trial enrolling 163 ALK-positive NSCLC had disease progression (91%) intolerance Patients received at starting dose 750 mg...
On November 13, 2013, the FDA granted accelerated approval to ibrutinib (IMBRUVICA capsules; Pharmacyclics, Inc.) for treatment of patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. February 12, 2014, chronic lymphocytic leukemia (CLL) Ibrutinib is a first-in-class Bruton's tyrosine kinase (BTK) inhibitor that all four expedited programs FDA: Fast-Track designation, Breakthrough Therapy Priority Review, and Accelerated Approval. Both approvals were based...
Background Small for gestational age (SGA) has been associated with increased risks of stillbirth and neonatal mortality, but data on long-term childhood mortality are scarce. Maternal antenatal care, including globally reducing the risk SGA birth, may be key to achieving Millennium Development Goal under-5 mortality. We therefore aimed examine association between from 28 days <18 years using a population-based sibling control design. Methods findings In Swedish population study, we...
Abstract Objective To assess whether severe psychiatric reactions to trauma and other adversities are associated with subsequent risk of life threatening infections. Design Population sibling matched cohort study. Setting Swedish population. Participants 144 919 individuals stress related disorders (post-traumatic disorder (PTSD), acute reaction, adjustment disorder, reactions) identified from 1987 2013 compared 184 612 full siblings a diagnosed 1 449 190 without such diagnosis the general...
Abstract Although major depression, characterized by a pro-inflammatory profile, genetically overlap with autoimmune disease (AD) and the perinatal period involve immune system adaptations AD symptom alterations, bidirectional link between depression (PND) is largely unexplored. Hence, objective of this study was to investigate association PND AD. Using nationwide Swedish population health registers, we conducted nested case-control matched cohort study. From 1,347,901 pregnancies during...
Abstract Background and Aims Increasing evidence suggests that some reproductive factors/hazards are associated with a future risk of cardiovascular disease (CVD) in women. While major (non-perinatal) depression has consistently been CVD, the long-term CVD after perinatal (PND) is largely unknown. Methods A nationwide population-based matched cohort study involving 55 539 women diagnosed PND during 2001–14 Sweden 545 567 unaffected individually on age year conception/delivery was conducted....
The true incidence of ovarian tumors in children is unknown. Few studies beyond case reports and series have been published concerning pediatric tumors. Herein we review a large number tumor cases.The charts 203 patients who presented with adnexal masses were reviewed.The patient's ranged age from 2 to 18 years (mean = 15.6 years), 30 being premenarchal (14.8%). increases age, especially older than 14 years. main complaint was abdominal pain or distension 117 (57.7%). A high AFP level...
Purpose To examine whether maternal cancer during pregnancy is associated with increased risks of stillbirth and infant mortality. Methods On the basis nationwide health registers, we conducted a study 3,947,215 singleton births in Sweden from 1973 through 2012. Exposure was defined as diagnosed (number = 984) or year after 2,723). We calculated incidence rate ratios (IRRs) for mortality, comparing exposed to unexposed births. Small-for-gestational-age (SGA) preterm were examined secondary...
Background: Adverse childhood experiences (ACEs) have consistently been associated with elevated risk of multiple adverse health outcomes, yet their contribution to coping ability and psychiatric resilience in adulthood is unclear. Methods: Cross-sectional data were derived from the ongoing Stress-And-Gene-Analysis cohort, representing 30% Icelandic nationwide female population, 18–69 years. Participants current study 26,198 women on 13 ACEs measured ACE-International Questionnaire....