Sagar Khadanga

ORCID: 0000-0002-8126-4459
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • Antibiotic Resistance in Bacteria
  • Antibiotic Use and Resistance
  • Mycobacterium research and diagnosis
  • Tuberculosis Research and Epidemiology
  • Long-Term Effects of COVID-19
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Cardiovascular Health and Risk Factors
  • Thermal Regulation in Medicine
  • Diagnosis and treatment of tuberculosis
  • Blood Pressure and Hypertension Studies
  • Diabetes Management and Research
  • Infectious Diseases and Mycology
  • Global Public Health Policies and Epidemiology
  • Respiratory Support and Mechanisms
  • Pain Mechanisms and Treatments
  • COVID-19 and Mental Health
  • Heart Rate Variability and Autonomic Control
  • Diabetes Management and Education
  • Burkholderia infections and melioidosis
  • Botulinum Toxin and Related Neurological Disorders
  • Amoebic Infections and Treatments
  • Gastrointestinal disorders and treatments
  • Clostridium difficile and Clostridium perfringens research
  • SARS-CoV-2 and COVID-19 Research

All India Institute of Medical Sciences Bhopal
2016-2025

K J Somaiya Medical College
2024

United Health Services
2024

Osmania Medical College
2024

Indian Council of Medical Research
2021-2024

Mahatma Gandhi Memorial Medical College
2023

OpenAI (United States)
2023

Indian Institute of Science Education and Research, Bhopal
2023

All India Institute of Medical Sciences
2020

Yahoo (United Kingdom)
2016

Critically ill coronavirus disease 2019 (COVID-19) patients need hospitalization which increases their risk of acquiring secondary bacterial and fungal infections. The practice empiric antimicrobial prescription, due to limited diagnostic capabilities many hospitals, has the potential escalate an already worrisome resistance (AMR) situation in India. This study reports prevalence profiles infections (SIs) clinical outcomes hospitalized COVID-19 India.A retrospective admitted intensive care...

10.2147/idr.s299774 article EN cc-by-nc Infection and Drug Resistance 2021-05-01

Background: The disease severity, ranging from being asymptomatic to having acute illness, and associated inflammatory responses has suggested that alterations in the gut microbiota may play a crucial role development of chronic disorders due COVID-19 infection. This study describes dysbiosis patients its implications relating disease. Design: A cross sectional prospective was performed on thirty RT-PCR-confirmed admitted All India Institute Medical Sciences, Bhopal, India, between September...

10.3390/microorganisms9061292 article EN cc-by Microorganisms 2021-06-13

Background: Metabolic syndrome (MetS) is a constellation of high blood pressure, hyperglycemia, obesity, and dyslipidemia. Its presence makes the patient more prone for cardiovascular events. prevalence has been documented as 11%–41%. The present study was undertaken to find out demographic profile MetS in Kanpur region northern India. Materials Methods: This hospital based, cross-sectional with adequate sample size. Results: Out randomly selected 420 patients (232 males 188 females), 172...

10.4103/jfmpc.jfmpc_10_17 article EN cc-by-nc-sa Journal of Family Medicine and Primary Care 2018-01-01

A BSTRACT Diabetic autonomic neuropathy is one of the most common complications diabetes which asymptomatic in early stage. Hence HRV and AFT are performed to detect prevent its progression advanced stages. To discuss findings diabetic patients. An observational study was conducted Physiology department AIIMS, Bhopal collaboration with Medicine institute. Seventy-two diagnosed Type-2 Diabetes mellitus patients were examined using POWER LAB AND CHART 8 BY AD INSTRUMENT: For recording heart...

10.4103/jfmpc.jfmpc_1128_24 article EN cc-by-nc-sa Journal of Family Medicine and Primary Care 2025-01-01

Antimicrobial resistance (AMR) poses a global health threat, emphasizing the need for Point Prevalence Surveys (PPS) to understand antibiotic use and resistance. This study assesses patterns in tertiary care hospitals across India inform AMR interventions. cross-sectional survey was conducted over two weeks between May August 2023 eight Indian hospitals. The comprised parts: ward form, which captured details (name, specialty, bed count, use), patient documented demographics, antimicrobial...

10.1016/j.eclinm.2025.103175 article EN cc-by-nc-nd EClinicalMedicine 2025-04-01

Diabetic peripheral neuropathy (DPN) if detected early can reduce the burden on health system and prevent development of diabetic foot ulcers amputation.To study effectiveness Semmes Weinstein 10 gm monofilament in detecting DPN taking nerve conduction studies (NCS) autonomic function testing (AFT) as reference tests.Observational comparative cross-sectional conducted Physiology department AIIMS, Bhopal collaboration with Medicine institute.A total 72 diagnosed type-2 diabetes mellitus...

10.4103/jfmpc.jfmpc_195_22 article EN cc-by-nc-sa Journal of Family Medicine and Primary Care 2022-10-01

Cirrhosis progression varies greatly from patient to due a variety of factors, including hepatic reserve, cirrhosis etiology, and the presence hepatocellular cancer. As result, determining prognosis in with remains difficult task. For nearly three decades, Child-Pugh score (CPS) has been gold standard for cirrhosis. In last two many prognostic models scores like model end-stage liver disease (MELD), chronic failure-sequential organ failure assessment (CLIF-SOFA) score, peripheral blood...

10.7759/cureus.21226 article EN Cureus 2022-01-14

Hymenolepis diminuta also known as rat tapeworm rarely causes hymenolepiasis in humans. We report a case of H. infection an 18-year-old male farmer who presented with intermittent pruritic maculopaular rashes and dull aching left iliac fossa pain for 6 months. Patient was cured 2 doses praziquantel 20 mg/kg on day 0 7.

10.4103/2229-5070.122145 article EN Tropical parasitology 2013-01-01

There is very limited data on the usefulness of pulmonary rehabilitation in patients with coronavirus pneumonia who have survived intensive care unit care. The primary aim was to explore feasibility conducting a program disease-19 surviving secondary study impact hospital-based 6-week exercise capacity, quality life, and psychological parameters these patients. This conducted at Center for Pulmonary Rehabilitation, Department Medicine institute.A total 27 were enrolled. Among them, 14...

10.5152/turkthoracj.2022.21159 article EN cc-by-nc Turkish Thoracic Journal 2022-03-30

Variations in blood glucose levels over a given time interval is termed as glycemic variability (GV). Higher GV associated with higher diabetes-related complications. The current study was done the aim of detecting sensitivity various indices among individuals type 2 diabetes mellitus different control status.We performed longitudinal (T2DM) who were participating two-week self-management education (DSME) program. Participants categorized by their HbA1c poor (≥8%), acceptable (7%⁻8%), and...

10.3390/medsci7030052 article EN cc-by Medical Sciences 2019-03-25

The misuse of antibiotics in recent years has led to an increase antibiotic associated diarrheas (AAD). Out several implicated pathogens, Clostridioides difficile is responsible for causing 15-25% all cases AAD. However, it remained under diagnosed a long time. current study planned explore prevalence C. amongst AAD patients and clinical presentation risk factors.Hospital based cross sectional conducted above 2 age. Diagnosis was done by two modalities i.e. glutamate dehydrogenase test...

10.18502/ijm.v15i1.11918 article EN cc-by-nc Iranian Journal of Microbiology 2023-02-13

Tuberculous meningitis (TBM) is a manifestation of extrapulmonary tuberculosis (EPTB) caused by Mycobacterium (MTB). The central nervous system involved in about 1%-2% all current (TB) cases and 7%-8% EPTB. if not treated early, TBM leads to high rate neurological sequelae mortality.This study aimed assess the diagnostic performance GeneXpert MTB/rifampicin (RIF) assay patients with TBM.A total 100 suspected were enrolled from various departments at tertiary care hospital, Bhopal, Madhya...

10.7759/cureus.37761 article EN Cureus 2023-04-18

Introduction Mycobacterium tuberculosis complex (MTBC), the primary cause of (TB), must be accurately identified to implement effective patient management and control strategies. Non-tuberculous mycobacteria (NTM) in suspected TB cases can result erroneous diagnoses needless treatment. Objective The study aimed identify NTM patients at a tertiary care hospital central India using molecular methods. Methods This prospective enrolled 400 pulmonary extra-pulmonary patients. Patients between age...

10.7759/cureus.39992 article EN Cureus 2023-06-05

Background and aimsCoronavirus disease (COVID-19) exhibits a range of clinical symptoms, including viral pneumonia, which can progress to acute respiratory distress syndrome, substantial alveolar destruction, even multi-organ failure in severe cases. Disease pathology is greatly influenced by the host immune response. Several studies reported perturbation T-cell responses COVID-19 patients. Activation differentiation CD4+ T cells into various subsets depend on expression lineage-specific...

10.14218/ge.2023.00016 article EN cc-by-nc Gene Expression 2023-08-23

Ultrasensitive immunosensing device based on bio-functionalized C 3 N 4 /RGO nanocomposite allows for exact differentiation between positive and negative real COVID-19 patient samples.

10.1039/d3ma00399j article EN cc-by-nc Materials Advances 2023-01-01

Introduction: Digital health innovations are modern solutions for the management and treatment of diseases, particularly non-communicable diseases. This study was conducted to assess feasibility diabetes hypertension through patient-generated data (PGHD). Methods: A mobile application (One Health) used entry on blood pressure, glucose, physical activity, dietary intake six months by patients. Frequency download, monthly entry, change in control pressure glycemic markers during use were...

10.7759/cureus.55060 article EN Cureus 2024-02-27

Melioidosis is caused by the Gram-negative bacilli Burkholderia pseudomallei, which found in contaminated water and soil spreads via inhalation, inoculation, ingestion. manifests diversely immunocompetent immunocompromised patients, ranging from asymptomatic to life-threatening respiratory distress, septic shock, localized tissue infection, necrotizing pneumonia, soft organ abscesses. Methods: An 18-month observational study was conducted at a tertiary center central India among various...

10.7759/cureus.43439 article EN Cureus 2023-08-13

Antimicrobial resistance (AMR) is a global concern requiring immediate attention. Among many proven measures of decreasing AMR, practice antimicrobial stewardship the lowest hanging which can be adapted with negligible financial implications.

10.4103/jfmpc.jfmpc_1473_20 article EN cc-by-nc-sa Journal of Family Medicine and Primary Care 2021-02-01

Introduction Antimicrobial resistance (AMR) has become a global pandemic. In order to identify this menace, World Health Organisation (WHO) developed the Global Action Plan on AMR (GAP AMR). stewardship programs (AMSP) have been identified as decisive tool for combating AMR. One of most efficient measures these implementation point prevalence surveys (PPS) antibiotic usage and subsequent audit feedback. The present study was undertaken impact AMSP curtailing empirical antibiotics...

10.7759/cureus.18517 article EN Cureus 2021-10-05

Abstract In urban India, about 35-40% of all adults have hypertension and 10-15% diabetes mellitus. National Program for Prevention Control Diabetes, Cancer Stroke (NPCDCS) launched by Government India has envisaged to screen aged 30 years above presence mellitus in the community through population-based screening, initiate positively screened diagnosed on drug therapy, follow them up treatment adherence. this context, current study aims estimate burden high cardiovascular disease (CVD) risk...

10.1101/2020.09.18.20189639 preprint EN cc-by-nc medRxiv (Cold Spring Harbor Laboratory) 2020-09-18

This article describes a case of melioidosis, severe and potentially fatal disease caused by the Gram-negative bacillus Burkholderia pseudomallei, in 55-year-old female India. The is endemic Southeast Asia Northern Australia. Recently there has been an increased number cases reported source B. pseudomallei India thought to be soil water, with most common mode infection being through skin contact. clinical presentation melioidosis varies greatly, making diagnosis difficult. presented here...

10.7759/cureus.36122 article EN Cureus 2023-03-14

Diabetes mellitus (DM) is characterized by increase in blood glucose levels due to defective insulin secretion or sensitivity. Interleukins (ILs) are known play an important role the pathogenesis of DM. The aim this study was investigate serum concentration IL-33 and its receptor soluble ST2 (sST2) patients with diabetes draw a correlation between their different standard glycaemic indices affected type-2 without metabolic syndrome.Thirty diabetic individuals 30 healthy controls were...

10.4103/ijmr.ijmr_1444_19 article EN The Indian Journal of Medical Research 2023-01-01

A middle-aged woman presented in shock with bleeding per rectum for 2 days without any significant past medical or surgical illness. Abdominal sonography, oesophagogastroduodenoscopy and sigmoidocolonoscopy were unremarkable. Despite 6 units of blood transfusion, 3000 mL plasma expanders ionotropes, the arterial pressure gradually decreased. We had no choice but to undergo life-threatening yet possibly life saving laparotomy. found a 1×1 cm ileal mucosal polyp about 20 away from ileocaecal...

10.1136/bcr-2015-213688 article EN BMJ Case Reports 2016-02-12

Secondary infections (SI) in COVID-19 have been documented from 3.6% to 72% various studies with mortality ranging 8.1% 57.6%. There is a gap knowledge for clinico-epidemio-microbilogical association among patients concomitant SI.This retrospective chart review, central India. The study was undertaken hospitalized adult during 1st June 2020 30th November 2020, laboratory proven infection and secondary infection.Out of the total 2338 number patients, only 265 (11.3%) were investigated...

10.2147/idr.s355742 article EN cc-by-nc Infection and Drug Resistance 2022-04-01

India has witnessed a major shift in morbidity to non-communicable diseases (NCDs) the last few decades. The service delivery for these long-term conditions been physician-centred up till now. There is recent move towards shared care, and nurses are being engaged of NCD care. This study was performed context composite training initiative involving doctors. Our aim compare performance with doctors determine which skills need be emphasised future educational programmes. Baseline end-training...

10.1080/14739879.2019.1619097 article EN Education for Primary Care 2019-06-03
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