- Nematode management and characterization studies
- Soil Carbon and Nitrogen Dynamics
- Legume Nitrogen Fixing Symbiosis
- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Essential Oils and Antimicrobial Activity
- Plant Parasitism and Resistance
- Phytochemicals and Antioxidant Activities
- Agriculture and Biological Studies
- Mycorrhizal Fungi and Plant Interactions
- Soybean genetics and cultivation
- Traditional Chinese Medicine Analysis
- DNA Repair Mechanisms
- PARP inhibition in cancer therapy
- Allelopathy and phytotoxic interactions
- Plant pathogens and resistance mechanisms
- Renal Diseases and Glomerulopathies
- Immune cells in cancer
- Pharmacological Effects and Toxicity Studies
- Galectins and Cancer Biology
- Neonatal and fetal brain pathology
- Environmental and Agricultural Sciences
- Epilepsy research and treatment
- Protein Tyrosine Phosphatases
- Magnolia and Illicium research
Sun Yat-sen Memorial Hospital
2024
Sun Yat-sen University
2024
South China Agricultural University
2004-2024
Northwest A&F University
2020-2023
Institute of Soil and Water Conservation
2021-2023
Chinese Academy of Sciences
2021-2023
Ministry of Water Resources of the People's Republic of China
2021-2023
University of California Davis Medical Center
2022
Shanghai Institute of Pharmaceutical Industry
2016-2018
Hefei First People's Hospital
2018
This research aimed to identify stable quantitative trait loci (QTL) associated with oil and protein content in soybean. A population of 196 recombinant inbred lines (RILs) derived from Huachun 2 × Wayao was used evaluate these target traits. high-density genetic linkage map constructed by using high-throughput genome-wide sequencing technology, which contained 3413 recombination bin markers spanned 5400.4 cM an average distance 1.58 between markers. Eighteen QTLs controlling were detected....
Abstract Background To date, although most thyroid carcinoma (THCA) achieves an excellent prognosis, some patients experience a rapid progression episode, even with differentiated THCA. Nodal metastasis is unfavorable predictor. Exploring the underlying mechanism may bring deep insight into Methods A total of 108 THCA from Chinese next-generation sequencing (NGS) were recruited. It was used to explore gene alteration spectrum and identify alterations related nodal in papillary (PTC). The...
Pod shattering is an important domesticated trait which can cause great economic loss of crop yield in cultivated soybean. In this study, we utilized two recombinant inbred line populations (RILs, CY, Huachun 2×Wayao; GB, Guizao 1×B13) to identify quantitative loci (QTLs) associated with pod soybean across multiple environments. A total 14 QTLs for were identified the RIL populations, had LOD scores ranging from 2.64 44.33 phenotypic variance explanation (PVE) 1.33 50.85%. One QTL qPS16-1,...
The bottom-up effects of vegetation have been documented to be strong drivers the soil food web structure and functioning in temperate forests. However, how forest type affects stability is not well known. In Ziwuling region Loess Plateau, we selected three typical forests, Pinus tabuliformis Carrière (PT), Betula platyphylla Sukaczev (BP), Quercus liaotungensis Koidz. (QL), investigate nematode community characteristics dry (April) rainy (August) season, analyzed their relationships with...
Abstract Breast cancers involving mutations in homologous recombination (HR) genes, most commonly BRCA1 and BRCA2 ( BRCA1/2 ), respond well to PARP inhibitors platinum‐based chemotherapy. However, except for these specific HR it is not clear which other contribute defects (HRD). Here, we performed next‐generation sequencing of tumor tissues matched blood samples from 119 breast cancer patients using the OncoScreen Plus panel. Genomic mutation characteristics HRD scores were analyzed. In...
Abstract The development of the embryo sac is an important factor that affects seed setting in rice. Numerous genes associated with (ES) have been identified plants; however, function DEAD-box RNA helicase family poorly known Here, we characterized a rice protein, RH52A, which localized nucleus and cytoplasm highly expressed floral organs. knockout mutant rh52a displayed partial ES sterility, including degeneration (21%) presence double-female-gametophyte (DFG) structure (11.8%). DFG...
Soil nematode communities can offer valuable indicators for monitoring the status of soil ecosystems. However, their potential assessing restoration under revegetation has been neglected in temperate arid and semiarid areas. This study examined characteristics relationships with physicochemical properties five typical approaches Loess Plateau China. The results showed that planting an artificial Caragana korshinskii forest led to recovery food web, which significantly increased abundance...
The establishment of Medicago sativa artificial grasslands is an important practice grassland vegetation restoration in the Loess Plateau. Understanding community characteristics soil microbes and nematodes can provide information for evaluating controlling ecolo-gical environmental effects restoration. In this study, we used M. with four different cultivation years (1, 2, 6 12 years) southern Ningxia mountainous region, a farmland natural as control, to explore changing trends two...
Refractory epilepsy is a common and troublesome neurosurgical disease. This study designed to compare seizure control degrees in intellectual outcome children with refractory after surgical treatment.20 were treated tailored surgery or vagus nerve stimulation (VNS). We used the Engel Epilepsy Surgery Outcome Scale evaluate Wechsler Intelligence for Children, fourth edition (WISC-IV), test children's outcomes 7-day preoperative 3-, 6-, 12-month postoperative.In total, 14 cases free (Engel I)...
A method using liquid chromatography-electrospray ionization ion trap mass spectrometry was established for the identification of metabolites in feces, urine and bile rats after oral administration 3′,4′-dimethoxy flavonol-3-β-d-glucopyranoside (abbreviated DF3G). Seven rat were firstly identified on basis their MS fragmentation behaviors. Three 6 2 bile, which suggested that demethylation, deglycosylation followed by glucuronide conjugation major metabolic pathways DF3G vivo. Hydrolyzation...
mutations and homologous recombination deficiency (HRD) occur frequently in breast cancer. However, the characteristics of
Abstract Protein tyrosine phosphatase receptors (PTPRs) play a crucial part in numerous tumor processes. However, the effect of PTPR mutations on immune checkpoint inhibitor (ICI) response needs to be further clarified. Next‐generation sequencing was performed 453 cancer patients our internal cohort. The genomic alterations, mutation burden (TMB), neoantigens, and immune‐related features/pathways other cohorts were analyzed. Here, protein receptor type D (PTPRD) has high frequency an...
Interactions between aboveground–belowground communities play an important role in regulating terrestrial ecological processes; however, the interactions rice varieties, herbivory and soil community are often ignored. A pot experiment with a full 2×2 factorial design was conducted to examine impacts of brown planthopper (Nilaparvata lugens) variety (susceptible or resistant) on nematode community. The results showed that, after nine days, aboveground significantly (P
Soil nematode communities play an important role in ecosystem material cycling and energy flow. In this study, soil samples were collected from three rotation systems southern Ningxia mountainous region, including alfalfa continuous cropping (A-A), alfalfa-corn (A-C), alfalfa-potato (A-P). physicochemical properties, community composition their metabolic footprints measured. Compared with the A-A plot, concentrations of organic carbon (SOC) total nitrogen (TN) significantly increased by 4.6%...