A5100652896- Genomics and Phylogenetic Studies
- Soybean genetics and cultivation
- Legume Nitrogen Fixing Symbiosis
- Plant Stress Responses and Tolerance
- Genetic Mapping and Diversity in Plants and Animals
- Chromosomal and Genetic Variations
- Plant Gene Expression Analysis
- Plant biochemistry and biosynthesis
- Phytase and its Applications
- Mycotoxins in Agriculture and Food
- GABA and Rice Research
- Plant Disease Resistance and Genetics
- Plant-Microbe Interactions and Immunity
- Microbial Metabolic Engineering and Bioproduction
- Pancreatic and Hepatic Oncology Research
- Ziziphus Jujuba Studies and Applications
- Connective Tissue Growth Factor Research
- Plant Pathogenic Bacteria Studies
- Enzyme Production and Characterization
- interferon and immune responses
- Plant Reproductive Biology
- Aquaculture disease management and microbiota
- Photosynthetic Processes and Mechanisms
- Plant Molecular Biology Research
- Pluripotent Stem Cells Research
Agricultural Genomics Institute at Shenzhen
2024-2025
Ministry of Agriculture and Rural Affairs
2024-2025
Chinese Academy of Agricultural Sciences
2000-2025
South China Agricultural University
2020-2024
Beijing Forestry University
2024
Air Force Medical University
2024
Xijing Hospital
2024
Beijing Academy of Science and Technology
2024
Mudanjiang Medical University
2022
Zhengzhou Fruit Research Institute
2021
Paclitaxel is a well known anticancer compound. Its biosynthesis involves the formation of highly functionalized diterpenoid core skeleton (baccatin III) and subsequent assembly phenylisoserinoyl side chain. Despite intensive investigation for half century, complete biosynthetic pathway baccatin III remains unknown. In this work, we identified bifunctional cytochrome P450 enzyme [taxane oxetanase 1 (TOT1)] in
Cadmium (Cd) is a widespread pollutant that toxic to living organisms. Previous studies have identified certain WRKY transcription factors, which confer Cd tolerance in different plant species. In the present study, we 29 Cd-responsive genes Soybean [Glycine max (L.) Merr.], and confirmed 26 of those GmWRKY were up-regulated, while 3 down-regulated. We also cloned novel, positively regulated GmWRKY142 gene from soybean investigated its regulatory mechanism tolerance. was highly expressed...
Petal blotch is a specific flower color pattern commonly found in angiosperm families. In particular, Rosa persica characterized by dark red blotches at the base of yellow petals. Modern rose cultivars with inherited trait from R. persica. Therefore, understanding mechanism for formation crucial breeding various patterns. this study, metabolites and genes responsible were identified first time through metabolomic transcriptomic analyses using LC-MS/MS RNA-seq. A total 157 flavonoids...
Lipoprotein (a) [Lp(a)] is an independent risk factor for atherosclerosis-related events that under strong genetic control (heritability = 0.68–0.98). However, causal mutations and functional validation of biological pathways modulating Lp(a) metabolism are lacking. We performed a genome-wide association scan to identify variants associated with Lp(a)-cholesterol levels in the Old Order Amish. confirmed previously known locus on chromosome 6q25-26 found also be significantly SNP near...
Deciphering the hereditary mechanism of seed iron (Fe) and zinc (Zn) content in soybean is important sustainable to address "hidden hunger" that presently affects approximately 2 billion people worldwide. Therefore, order detect genomic regions related Fe Zn content, a recombinant inbred line (RIL) population with 248 lines was assessed four environments Quantitative Trait Loci (QTLs) content.Wide variation found environments, genotype, environment, genotype × environment interactions had...
Abstract Background The fungus Aspergillus flavus ( A. ) is a serious threat to maize Zea mays production worldwide. It causes considerable yield and economic losses, poses health risk humans livestock due the high toxicity of aflatoxin. However, key genes regulatory networks conferring resistance are not clear, especially at early stage infection. Here, we performed comprehensive transcriptome analysis two inbred lines with contrasting Results pairwise comparisons between mock infected...
Groupers are an economically important fish species in world fishery markets. Because many studies using RT-qPCR have addressed gene expression groupers, appropriate reference genes required to obtain reliable and accurate results. In this study, the most suitable were identified from eleven candidate of one valuable species, Epinephelus akaara, a range different experimental conditions. Using software packages geNorm, NormFinder, BestKeeper refFinder, three traditionally used genes, β-actin...
Abstract Bacterial pathogens from the genus Pectobacterium cause soft rot in various plants, and result important economic losses worldwide. We understand much about how these digest their hosts protect themselves against plant defences, as well some regulatory networks processes. However, spatiotemporal expression of genome‐wide infection remains unclear, although researchers analysed this phytopathogens. In present work, comparing transcriptome profiles cellular with growth minimal rich...
Abstract Background Peritoneal fibrosis is the prevailing complication induced by prolonged exposure to high glucose in patients undergoing peritoneal dialysis. Methods To elucidate molecular mechanisms underlying this process, we conducted an integrated analysis of transcriptome and chromatin accessibility profiles human mesothelial cells (HMrSV5) during high-glucose treatment. Results Our study identified 2775 differentially expressed genes (DEGs) related glucose-triggered pathological...
Abstract Indian jujube (Ziziphus mauritiana) holds a prominent position in the global fruit and pharmaceutical markets. Here, we report assemblies of haplotype-resolved, telomere-to-telomere genomes autotetraploid wild cultivated plants using two-stage assembly strategy. The generation these permitted in-depth investigations into divergence evolutionary history this important crop. Using graph-based pan-genome constructed from eight monoploid genomes, identified structural variation (SV)-FST...
Pod shattering is an important domesticated trait which can cause great economic loss of crop yield in cultivated soybean. In this study, we utilized two recombinant inbred line populations (RILs, CY, Huachun 2×Wayao; GB, Guizao 1×B13) to identify quantitative loci (QTLs) associated with pod soybean across multiple environments. A total 14 QTLs for were identified the RIL populations, had LOD scores ranging from 2.64 44.33 phenotypic variance explanation (PVE) 1.33 50.85%. One QTL qPS16-1,...
The public concern for radioactivity of drinking-water has been increasing in recent years after the rapid development nuclear power plants, and especially Fukushima accident. In this study, water samples collected vicinity facilities from seven provinces China was measured an average annual equivalent effective dose derived ingestion calculated. results showed that, winter spring, activities gross α β ranged 0.009 Bq/L to 0.200 0.067 0.320 Bq/L, respectively. While, summer autumn, a varied...
Carbonic anhydrase 3 (CA3) is a member of the carbonic family, which plays an important role in various cell processes. In this paper, molecular characterization revealed that <i>CA3</i> genomic DNA consists seven exons and six introns, spans about 10.5 kb maps to porcine chromosome 4q11→q14. Results expression profiles showed levels increased skeletal muscles from prenatal 33- 65-day-old Chinese Tongcheng pigs. These subsequently decreased steady state 90-day-old, postnatal...
Abstract Background Autophagy, meaning ‘self-eating’, is required for the degradation and recycling of cytoplasmic constituents under stressful non-stressful conditions, which helps to maintain cellular homeostasis delay aging longevity in eukaryotes. To date, functions autophagy have been heavily studied yeast, mammals model plants, but few studies focused on economically important crops, especially tea plants ( Camellia sinensis ). The roles played by coping with various environmental...
Jujube (Ziziphus jujuba Mill.), belonging to the Rhamnaceae family, is gaining increasing prominence as a perennial fruit crop with significant economic and medicinal values. Here, we conduct de novo assembly of four reference-grade genomes, encompassing one wild three cultivated jujube accessions. We present insights into population structure, genetic diversity, genomic variations within diverse collection 1059 Analyzes pan-genome, based on our assemblies previously released reveal...
In this study, two enolase genes were isolated and characterized from the Chinese oak silkworm, Antheraea perny, which designated as I II, respectively. The cDNA sequence was 1712 bp with an open reading frame (ORF) of 1302 encoding 433 amino acids. II 1549 ORF 1296 431 acid sequences share several conserved features/sites enolase. pernyi shows 93%-97% identity to enolases lepidopterans available date, 75%-82% other invertebrates, 60%-72% organisms including vertebrates, plants, fungi. 84%...
A multilocus GWAS was performed to explore the genetic architecture of four growth traits in yak. In total, 354 female yaks for which measurements body weight (BW), withers height (WH), length (BL) and chest girth (CG) at weaning were available underwent genotyping with Illumina BovineHD BeadChip (770K). After quality control, we retained 98 688 SNPs animals analysis. We identified seven, 18, seven nine (corresponding 17, eight candidate genes) associated BW, WH, BL CG respectively....
Water deficit is an environmental factor that constrains crops to express their ecophysiological potential and causes crop yield reduction. Eruca vesicaria has been reported be one of the most drought-tolerant species in Cruciferae . In this study, polyethylene glycol-simulated drought tolerance was evaluated line Brassica carinata , napus 249 lines based on principal component analysis (PCA) unweighted pair-group arithmetic average (UPGMA) cluster analysis. The PCA eight indices indicated...
AtPID (Arabidopsis thaliana Protein Interactome Database, available at http://www.megabionet.org/atpid) is an integrated database resource for protein interaction network and functional annotation. In the past few years, we collected 5564 mutants with significant morphological alterations manually curated them to 167 plant ontology (PO) morphology categories. These single/multiple-gene were indexed linked 3919 genes. After these genotype-phenotype associations comprehensive in AtPID,...