A5101858882- Parasites and Host Interactions
- Parasite Biology and Host Interactions
- Papaya Research and Applications
- Insect Pest Control Strategies
- Aquaculture disease management and microbiota
- Date Palm Research Studies
- Mollusks and Parasites Studies
- Child Nutrition and Water Access
- Functional Brain Connectivity Studies
- Transcranial Magnetic Stimulation Studies
- Global Maternal and Child Health
- Helminth infection and control
- Lipid metabolism and biosynthesis
- Pancreatic function and diabetes
- Liver Disease and Transplantation
- Photosynthetic Processes and Mechanisms
- Liver Disease Diagnosis and Treatment
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Malaria Research and Control
- Plant biochemistry and biosynthesis
- Advanced Memory and Neural Computing
- Metabolomics and Mass Spectrometry Studies
- Gut microbiota and health
- Attention Deficit Hyperactivity Disorder
- Microbial Community Ecology and Physiology
Sun Yat-sen University
2014-2025
Hebei Medical University
2023
Second Hospital of Hebei Medical University
2023
South China Agricultural University
2019
Ministry of Education of the People's Republic of China
2017-2018
South China University of Technology
2016
China Agricultural University
2008
Background Schistosomiasis is a snail-borne parasitic disease and endemic in many tropical subtropical countries. Biomphalaria straminea, an intermediate host for Schistosoma mansoni, native to the southeastern part of South America has established other regions America, Central southern China during last decades. S. mansoni Africa, Middle East, Caribbean. Knowledge potential global distribution this snail essential risk assessment, monitoring, prevention control. Methods findings A...
Schistosomiasis mansoni is one of the most important, but often neglected, tropical diseases transmitted by snails genus Biomphalaria. Control intermediate host snail plays a crucial role in preventing spread schistosomiasis. However, there only molluscicide, niclosamide, recommended World Health Organization. Niclosamide has been used for several decades toxic to non-target organisms. Therefore, it necessary optimize scaffold niclosamide and develop novel molluscicides with enhanced potency...
Schistosomiasis japonica is a significant health problem that leads to morbidity and mortality of humans. It characterized by hepatic granulomatous response fibrosis caused eggs deposition in the liver. β-actin, traditional housekeeping gene, widely used as an internal control normalize gene protein expression. However, β-actin expression can fluctuate upon treatment with pharmacological agents or under some physiological pathological conditions. In this study, we found expressions both mRNA...
Angiostrongylus cantonensis invades the central nervous system (CNS) of humans to induce eosinophilic meningitis and meningoencephalitis leads persistent headache, cognitive dysfunction, ataxic gait. Infected mice (nonpermissive host), admittedly, suffer more serious pathological injuries than rats (permissive host). However, basis these manifestations is incompletely elucidated. In this study, behavioral test, histological immunohistochemical techniques, analysis apoptotic gene expression,...
Amphioxus is a typical filter feeder animal and confronted with complex bacterial community in the seawater of its habitat. It has evolved strong innate immune system to cope external stimulation, however, ecological remains unknown. Through massive parallel 16S rRNA gene tag pyrosequencing, investigation indicated that composition wild lab-cultured fecal bacteria was more than 85,000 sequence tags being assigned 12/13 phyla. The diversity between two samples similar according OTU richness...
Chloramphenicol (Chl) is an effective antimicrobial agent widely used in veterinary medicine and commonly fish. Its use restricted the clinic because of adverse effects on immune system oxidative stress mammals. However, Chl treatment invertebrates remain unclear. Amphioxus, a basal chordate, ideal model to study origin evolution vertebrate as it has primary vertebrate-like arachidonic acid (AA) metabolic system. Here, we combined transcriptomic lipidomic approaches investigate observe...
Epilepsy, especially the medial temporal lobe epilepsy (TLE), can result in cognitive impairment. Low‑frequency repetitive magnetic stimulation (rTMS) has been verified to suppress neural excitability and reduce seizures. Given its potential modifying cortical activity, we aimed investigate impact on function context of epilepsy, a condition where use rTMS not extensively explored. However, influence yet investigated. Therefore, this study effects low‑frequency improvement epileptic rats....
Background: Schistosomiasis (japonica) is a neglected infectious disease, influencing millions of people at risk infection worldwide. The patients are high gradually developing hepatic fibrosis. Immune regulation recognized to contribute schistosomal liver However, we still lack appropriate preventive and therapeutic modalities. Previous evidence points out that there an interaction between lipid inflammation which moderates the homeostasis after parasitic infection. Moreover, while immune...