A5027053431- Ultrasound Imaging and Elastography
- Cardiovascular Health and Disease Prevention
- Coronary Interventions and Diagnostics
- Photoacoustic and Ultrasonic Imaging
- Cerebrovascular and Carotid Artery Diseases
- Ultrasound and Hyperthermia Applications
- Ion-surface interactions and analysis
- Integrated Circuits and Semiconductor Failure Analysis
- Cardiovascular Function and Risk Factors
- Photonic and Optical Devices
- Blood properties and coagulation
- Hemodynamic Monitoring and Therapy
- Non-Invasive Vital Sign Monitoring
- Cardiac Valve Diseases and Treatments
- Semiconductor materials and devices
- Elasticity and Material Modeling
- Peripheral Artery Disease Management
- Advanced X-ray and CT Imaging
- Hereditary Neurological Disorders
- Advanced Fiber Optic Sensors
- Semiconductor Quantum Structures and Devices
- Sepsis Diagnosis and Treatment
- Liver Disease Diagnosis and Treatment
- Peripheral Neuropathies and Disorders
- Child and Animal Learning Development
Centre Hospitalier de l’Université de Montréal
2010-2025
Université de Montréal
2011-2024
Inserm
2018
Neurocentre Magendie
2018
Hospices Civils de Lyon
2014
Montreal Heart Institute
2010-2012
Montreal Clinical Research Institute
1992-2005
Hôtel-Dieu de Montréal
1993-2005
Institute for Microstructural Sciences
1991-2002
McGill University
1998
Mitochondrial dysfunction in the spinal cord is a hallmark of amyotrophic lateral sclerosis (ALS), but neurometabolic alterations during early stages disease remain unknown. Here, we investigated bioenergetic and proteomic changes ALS mouse motor neurons patients' skin fibroblasts. We first observed that SODG93A mice presymptomatic display coupling efficiency oxidative phosphorylation, along with fragmentation mitochondrial network. The proteome also revealed peculiar metabolic signature...
People with HIV (PWH) have an increased risk of developing cardiovascular disease (CVD). Our recent data demonstrated that the multi-isoform proinflammatory cytokine IL-32 is upregulated in PWH and associated arterial stiffness subclinical atherosclerosis. However, mechanisms by which contributes to pathogenesis these diseases remain unclear. Here, we show while less expressed IL-32α isoform induces differentiation human classical monocytes into calcium-resorbing osteoclast cells, dominantly...
To develop a classification method based on the statistical backscatter properties of tissues that can be used as an ancillary tool to usual Breast Imaging Reporting and Data System (BI-RADS) for solid breast lesions identified at ultrasonography (US).This study received institutional review board approval, all subjects provided informed consent. Eighty-nine women (mean age, 50 years; age range, 22-82 years) with 96 indeterminate (BI-RADS category 4-5; mean size, 13.2 mm; 2.6-44.7 mm) were...
Locating and evaluating the length severity of a stenosis is very important for planning adequate treatment peripheral arterial disease (PAD). Conventional ultrasound (US) examination cannot provide maps entire lower limb arteries in 3-D. We propose prototype 3D-US robotic system with B-mode images, which nonionizing, noninvasive, able to track reconstruct continuous segment tree between groin knee. From an initialized cross-sectional view vessel, automatic tracking was conducted followed by...
Change in viscoelastic properties of biological tissues may often be symptomatic dysfunction that can correlated with tissue pathology. Shear wave (SW) elastography is an imaging method mainly used to assess stiffness but the potential measure viscoelasticity tissues. This enable characterization and, thus, as a marker improve diagnosis pathological lesions. In this study, frequency-shift method-based framework presented for reconstruction viscosity by analyzing spectral acoustic radiation...
Background Diabetic patients present higher level of red blood cell (RBC) aggregation contributing to the development vascular complications. While it has been suggested that this hematology/rheology parameter could bring additional prognostic information for management those patients, RBC screening is not included as a clinical practice. Most medical centers are equipped measure properly parameter, although sedimentation tests can some indication. Here, we aimed at evaluating feasibility...
The optical and structural properties of porous Si films produced by electrochemical chemical dissolution have been studied a variety techniques. Raman scattering transmission electron microscopy shown the samples to contain crystalline wires (or) spherites 3–8 nm in diameter amorphous Si. absorption spectra wavelength, temperature, lifetime dependence photoluminescence obtained from most are entirely consistent with quantum confinement excitons nanostructures. Quite different was other...
The objective was to design a vascular phantom compatible with digital subtraction angiography, computerized tomography ultrasound and magnetic resonance angiography (MRA). Fiducial markers were implanted at precise known locations in the facilitate identification orientation of plane views from three‐dimensional (3‐D) reconstructed images. A conduit connected tubing extremities ran through an agar‐based gel filling it. vessel wall latex included around avoid diffusion contrast agents. Using...
It has been reported that power color Doppler ultrasound important advantages over conventional flow imaging. Some of these are the aliasing free capability, increased sensitivity to flow, and angular independence. This last characteristic was evaluated verify if it still valid in some well-defined conditions where porcine whole blood, calf red cells suspended saline solution, carbon fibers a water-glycerol mixture were used as scattering particles. Experiments conducted under steady (mean...
Purpose: With the continuous development of new stent grafts and implantation techniques, it has now become technically feasible to treat abdominal aortic aneurysms (AAA) with challenging anatomy using endovascular repair standard, fenestrated, or branched stent‐grafts. In vitro experimentations are very useful improve stent‐graft design conformability imaging guidance for delivery follow‐up. Vascular replicas also help better understand limitation approaches in possibly surgical planning...
An enhanced inflammatory response is a trigger to the production of blood macromolecules involved in abnormally high levels erythrocyte aggregation.This study aimed at demonstrating for first time clinical feasibility non-invasive ultrasound-based aggregation quantitative measurement method potential application critical care medicine.Erythrocyte was evaluated using modeling backscatter coefficient with Structure Factor Size and Attenuation Estimator (SFSAE). SFSAE spectral parameters W...
Abstract In an attempt to assess infants' reactions one particular class of animate objects (animals), as opposed persons and inanimate objects, 57 babies between 9 10 months old were divided into three equal groups assigned experimental conditions, involving (a) a living unfamiliar dwarf rabbit, (b) novel toy, or (c) adult stranger. The same infant-controlled procedure was used in all the measured terms approach stimulus- well mother-directed looks, smiles, vocalizations. Results showed...
Low-temperature photoluminescence (PL) spectroscopy was used to estimate the compositional disordering induced by Ga focused-ion-beam implantation in a series of strained InGaAs/GaAs quantum wells (QW). A simple formalism derived indium concentration and degree interdiffusion QWs from observed shifts PL transition energies. study nanostructures indicated that lateral extent significantly larger than predicted spreading ion beam.
Multimodality vascular flow phantoms provide a way of testing the geometric accuracy clinical scanners and optimizing acquisition protocols with easy reproducibility experimental conditions. This article presents stereolithography method combined lost-material casting technique that eliminates metal residues cerrolow (a low temperature melting point metallic alloy) left within irregular vessel lumens after casting. These potentially cause image artifacts especially in magnetic resonance...
In many pathological conditions, including high-risk surgery, the severity of inflammatory response is related to patient outcome. However, determining state presents difficulties, as markers are obtained intermittently through blood testing with long delay. RBC aggregation a surrogate marker inflammation that can be quantified ultrasound Structure Factor Size and Attenuation Estimator. The latter proposed real-time monitoring technique for care.Ten swine underwent 90-minute cardiopulmonary...
The degree of stenosis is the most important criterion to assess peripheral arterial disease manifested by atherosclerosis mainly in lower limb arteries. Ultrasound (U.S.) imaging offers low-cost, safe, and convenient options evaluate this disease, but U.S. freehand approaches cannot optimally locate stenoses map geometries. A 3D-U.S. robotic system that can control standardize image acquisition scanning typically encountered diseased segments presented validated with phantoms.A Z-phantom...