A5101602095- Sustainability and Ecological Systems Analysis
- Traditional Chinese Medicine Studies
- Magnolia and Illicium research
- Agriculture Sustainability and Environmental Impact
- Cardiac Valve Diseases and Treatments
- Nuclear Receptors and Signaling
- Healthcare and Venom Research
- Thermochemical Biomass Conversion Processes
- Global Energy and Sustainability Research
- Macrophage Migration Inhibitory Factor
- Pharmacological Effects of Natural Compounds
- Coal and Coke Industries Research
- Sustainable Agricultural Systems Analysis
- Iron and Steelmaking Processes
- Plant tissue culture and regeneration
- Coal and Its By-products
- Cognitive Science and Mapping
- Mining and Gasification Technologies
- Biosimilars and Bioanalytical Methods
- Berberine and alkaloids research
- Geomechanics and Mining Engineering
- Text and Document Classification Technologies
- Enzyme Production and Characterization
- Hydraulic and Pneumatic Systems
- Innovative Microfluidic and Catalytic Techniques Innovation
Children's Hospital of Los Angeles
2025
University of Southern California
2025
Guangdong Pharmaceutical University
2017-2024
China National Pharmaceutical Group Corporation (China)
2022
Hubei University of Medicine
2022
Dongfeng General Hospital
2022
Peking University
2008-2017
Zhongnan University of Economics and Law
2017
China Agricultural University
2013-2016
Zaozhuang Municipal Hospital
2011
Over the past four decades, Bacillus biofertilizers, which are microbial formulations based on species, have significantly contributed to sustainable agriculture by enhancing crop growth, improving soil health, and reducing dependency chemical fertilizers. particularly known for their ability promote plant fix nitrogen, solubilize phosphorus, produce growth-promoting substances such as phytohormones antibiotics, emerged key players in development of eco-friendly agricultural solutions. This...
Herein, we sought to evaluate the contribution of 1,3,5-triazine ring through metformin cyclization unit biological activity magnolol and honokiol-conjugates. One phenolic OH groups or honokiol was replaced by a further explore their synthesis medicinal versatility. In this study, robust procedure three steps adopted for derivatives alkylation potassium carbonate with ring. To our knowledge, is first report connect one positions cyclized metformin. The structural characterization new...
The novel target products were synthesized in the formation of a triazine ring from berberine, magnolol, and metformin catalyzed by sodium methylate. structures 1-3 firstly confirmed extensive spectroscopic analyses single-crystal X-ray diffraction. crystal product 2 intermediate 7b reported for first time. All evaluated their anti-inflammatory antidiabetic activities against INS-1 RAW264.1 cells vitro all showed excellent effects anti-insulin resistance effects. Our studies indicated that...
Abstract Quercetin is a naturally existing flavonoid with numerous physiological effects, including antitumor activity. It functions as an agent by inducing apoptosis and inhibiting tumor cell development, preventing invasion metastasis, reversing multidrug resistance. has limited therapeutic usefulness due to its low water solubility, poor oral absorption, bioavailability. New quercetin derivatives are being developed manufactured via variety of methods address inadequacies for utilization...
Abstract Anemarrhena asphodeloides Bunge is a traditional Chinese medicine. The timosaponin BII one of the most abundant and widely studied active ingredients in . Related studies have shown that has potential value for development further utilization. protective effect on islet β cells under type 2 diabetes was investigated glycolipid toxic INS‐1 cell model possible biomarkers were explored by lipidomics analysis. Timosaponin isolated from polyamide resin Sephadex LH‐20. Then, toxicity...
In this study, we investigated the lipid metabolism regulatory activity of a novel metformin derivative (MD568) and its potential mechanism action in obese rats with type 2 diabetes mellitus (T
Danggui Jixueteng decoction (DJD) has been used to treat anemia for many years and shown be effective. However, the mechanism of action effective components are yet unknown. We want search pharmacodynamic in DJD with therapeutic effects on myelosuppression after chemotherapy (MAC), utilizing a spectrum-effect connection study based gray relational analysis partial least-squares regression analysis. Transcriptome sequencing (RNA-Seq) was investigate by which treats MAC. In this study,...
Based on the principle of molecular splicing and theory traditional Chinese medicine pairs, a new multi-active compound (HM475) was synthesized by connecting metformin with honokiol, its structure characterized, which not only reduced toxicity raw materials, but also maintained original activity, had certain significance in research innovation. At same time, quality control preliminary activity evaluation were carried out, effect HM475 neuroinflammation further explored, provided idea for...
To investigate the significance of echocardiography combined with N-terminal pro-B-type natriuretic peptide (NT-pro BNP) levels in evaluation and prognosis diastolic heart failure (DHF).Clinical data were collected from 168 patients DHF. Serum NT-pro BNP first measured by ELISA. Meanwhile, was used to examine left ventricular end-diastolic diameter (LVEDD), (LVD), other parameters. Multivariate logistic regression analysis performed for variables assessment grade or poor prognosis. Finally,...
In the last decade, embedded multi-label feature selection methods, incorporating search for subsets into model optimization, have attracted considerable attention in accurately evaluating importance of features classification tasks. Nevertheless, state-of-the-art algorithms based on least square regression usually cannot preserve sufficient discriminative information data. To tackle aforementioned challenge, a novel method, termed global redundancy and relevance optimization orthogonal...
The digital economy is currently sweeping the globe, with China leading way. Digital payments are quickly replacing cash as new currency of country's social progress. Nonetheless, middle-aged and older populations research objects this work because there still not enough studies on population. It makes pertinent recommendations for mobile banking to enhance security, expand auxiliary features, add network customer service in accordance elderly customers' needs based findings influencing...
Over the past four decades, Bacillus biofertilizers have significantly contributed to sustainable agricultural practices by enhancing crop growth, improving soil health, and reducing chemical dependencies. This research utilizes bibliometric analysis based on 3,242 documents sourced from Web of Science database map development, key contributions, innovation within field 1985 2023. The study identifies exponential growth in output, particularly 2003 onwards, indicating a robust interest...
In the past decade, rapid spread of multimedia and network technology leads to development information retrieval techniques, especially CBIR (content-based image retrieval) research. this paper, we introduce a system which applies hybrid method relevance feedback Earth Mover's Distance (EMD) algorithm. Given query image, can extract color feature, convert RGB space HSV space. attempt reduce drawback bin-by-bin distance, algorithm is utilized. What more, gap between features computer extracts...
For the increasingly complex information environment and changing target characteristics, most of existing multi-sensor fusion methods are "static", less consider influence sensor reliability change timeliness multi-dimensional feature index weight in measurement process on results. To solve this problem, an method based fuzzy theory interval multi-attribute decision making is proposed. The defines quality optimization degree from consistency support each to proposition, uses number define...
Objective To investigate the correlation between glycemic variability and sudomotor function in patients with type 2 diabetes mellitus (T2DM). Methods A total of 395 cases T2DM Department Endocrinology, Nanjing General Hospital PLA from March 2016 to May 2017 were enrolled. According electrical skin conductivities (ESC) hands feet measured SUDOSCAN, a conductance analyzer, divided into two groups: 221 normal (normal group, both ESC >60 μs, including 144 males, 77 females) 174 abnormal...