(1) Background: Obesity and diabetes continue to reach epidemic levels in the population with major health impacts that include a significantly increased risk of coronary atherosclerosis. The imbalance trace elements body caused by nutritional factors can lead progression (2) Methods: We measured concentrations sodium (Na), potassium (K), magnesium (Mg), calcium (Ca), Zinc (Zn), iron (Fe) peripheral blood samples from 4243 patients performed baseline analysis propensity matching patient...

Objective . To find molecular markers for the diagnosis of acute myocardial infarction (AMI), this research further verified relationship between expression level FFAR2 gene and AMI by expanding sample size based on previous chip results. Methods Peripheral venous leukocytes were collected from 113 patients with 94 noncoronary artery disease as experimental group control group, respectively. Real-time fluorescence quantitative polymerase chain reaction was used to detect gene. Western blot...

Objective: Coronary heart disease (CHD) is a complex caused by multifaceted interaction between genetic and environmental factors, which makes identification of the most likely candidate proteins their associated risk markers big challenge. Atherosclerosis presented broad spectrum diseases, including stable coronary artery (SCAD) acute myocardial infarction (AMI), progressive stage SCAD. As such, correct prompt diagnosis atherosclerosis turns into imperative for precise diagnosis, treatment...

Aims: The present study was designed to evaluate whether the expression of suppressor cytokine signaling 3 (SOCS3) gene could serve as a biomarker predict risk acute myocardial infarction (AMI). Basic Methods: Peripheral white blood cells were collected from 113 patients with AMI and 92 stable coronary artery disease (SCAD). SOCS3 mRNA levels in peripheral determined by real-time quantitative polymerase chain reaction, protein Western blotting. Results: 1.33-fold higher than that SCAD...

Background The transmembrane protein Notch1 is associated with cell growth, development, differentiation, proliferation, apoptosis, adhesion, and the epithelial mesenchymal transition. Proteomics, as a research method, uses series of sequencing techniques to study composition, expression levels, modifications proteins. Here, association between acute myocardial infarction (AMI) was investigated using proteomics, assess possibility biomarker for disease. Methods Fifty-five eligible patients...

Abstract Atherosclerosis refers to a disease characterized by the formation of lipid plaque deposits within arterial walls, leading reduced blood flow or blockage outflow. The process endothelial injury induced oxidized low‐density lipoprotein (ox‐LDL) is considered initial stage atherosclerosis. Ferroptosis form iron‐dependent, non‐apoptotic cell death, and current research suggests its association with coronary artery (CAD). In this study, we observed correlation between expression SREBP‐1...

Objective This study aimed to investigate whether differential expression of the retinoic acid receptor-related orphan receptor A ( RORA) gene is related occurrence acute myocardial infarction (AMI). Methods was a retrospective study. White blood cells 93 patients with and 74 stable coronary artery disease were collected. Reverse transcription quantitative polymerase chain reaction western blotting used measure RORA mRNA protein expression, respectively. Results levels in peripheral...

Abstract Background: The G0/G1 switch 2 (G0S2) gene is closely related to lipolysis, cell proliferation, apoptosis, oxidative phosphorylation, and the development of a variety tumors. aim present study was expand sample size confirm relationship between expression G0S2 in peripheral blood acute myocardial infarction (AMI) based on previous chip results. Methods: Three hundred patients were initially selected, which 133 excluded accordance with exclusion criteria. Peripheral leukocytes...

This study aimed to determine the amount of expression ATP-binding cassette subfamily B member 1 (ABCB1) gene chip as a prospective diagnostic marker for acute myocardial infarction (AMI) in wide population . In AMI and control groups, 113 patients with 83 persons non-coronary artery disease were selected peripheral venous leukocyte collection. Western blot real-time polymerase chain reaction (RT-PCR) employed detect relative ABCB1 both groups. The results showed that transcription protein...

ZCCHC9 is a zinc finger protein with CCHC structure and has important roles in several cellular processes. This study was conducted on an expanded number of samples to evaluate The usefulness gene expression peripheral blood as molecular marker for the prediction AMI (acute myocardial infarction) risk.Peripheral were collected from 117 patients stable CAD (coronary atherosclerotic disease) 126 AMI. mRNA level assessed by qRT-PCR, its determined Western blotting.The group exhibited reduced...

Our study's goal was to find out acute myocardial infarction (AMI) patients' NUMB gene expression patterns and evaluate its role as a diagnostic marker for AMI detection.Peripheral blood drawn from 124 individuals who had an 115 patients stable coronary artery disease (SCAD). The real-time quantitative polymerase chain reaction used measure the mRNA level of in peripheral blood.The group's 0.906 (0.181-0.954), whereas SCAD 1.024 (0.207-1.127). However, group 0.885 times lower than (P <...

The COVID-19 pandemic can be seen as a traumatic event during which time medical students have been required to perform dual roles both and workers. In this study, we aimed use the Perceived Stress Scale (PSS-14) judge pressures on identify effective ways relieve these pressures. cross-sectional subjects were recruited under informed consent according Declaration of Helsinki. Students undertaking Masters degrees at China-Japan Union Hospital Jilin University randomly selected data collected...

Abstract Urban expansion caused numerous geological hazards, particularly in the mountainous areas. In this article, unsaturated soil mechanics combined with a numerical method is applied to build rainfall thresholds for Xiangmi Lake slope early warning. The drainage mechanism under different conditions has been studied. Then, actual data collected rainy season are taken as condition simulate situation. corresponding safety factor of calculated and compared improved deformation tangential...

The current therapy for myocarditis is immunosuppressive therapy. However, in rare cases which patients do not respond to intervention, their condition can rapidly deteriorate with shock, characterized by extensive and diffuse lymphocyte infiltration the myocardium. Most of are caused virus-mediated damage cardiomyocytes, its clinical manifestations ventricular arrhythmia hemodynamic disturbances. Extracorporeal membrane oxygenation an effective regulates stability avoids systemic...