A5016679810- Cancer Risks and Factors
- Global Cancer Incidence and Screening
- BRCA gene mutations in cancer
- Health, Environment, Cognitive Aging
- Effects and risks of endocrine disrupting chemicals
- Birth, Development, and Health
- Cardiovascular Health and Risk Factors
- Ethics in Clinical Research
- COVID-19 and Mental Health
- Family Support in Illness
- Nutrition, Genetics, and Disease
- Nutritional Studies and Diet
- Hypothalamic control of reproductive hormones
- Epigenetics and DNA Methylation
- Digital Radiography and Breast Imaging
- Stress Responses and Cortisol
- Cancer survivorship and care
- Environmental Justice and Health Disparities
- Food Security and Health in Diverse Populations
- Estrogen and related hormone effects
- Health, psychology, and well-being
- Cancer Genomics and Diagnostics
- Air Quality and Health Impacts
- Hair Growth and Disorders
- Genomics and Rare Diseases
Columbia University
2015-2025
Columbia University Irving Medical Center
2016-2025
Harlem United
2023
Milken Institute
2023
George Washington University
2021
National Center on Addiction and Substance Abuse at Columbia University
2020
The Kids Research Institute Australia
2014
The University of Western Australia
2014
University of Pennsylvania
2011-2012
Community Based Research Centre
2012
Ages at menarche and first birth are established risk factors for breast cancer. The interval between these ages may also affect risk, since the is more susceptible to carcinogenic insults during this period than parous period. However, few investigators have studied relation. Using logistic regression, authors evaluated associations timing of reproductive events cancer among 4,013 cases 4,069 controls enrolled in a multicenter, population-based US case-control study White African-American...
Select hair products contain endocrine disrupting chemicals (EDCs) that may affect breast cancer risk. We hypothesize that, if EDCs are related to risk, then they also two important risk factors: age at menarche and mammographic density. In urban female cohorts (N = 248): 1) the New York site of National Collaborative Perinatal Project 2) City Multiethnic Breast Cancer Project, we measured childhood adult use oils, lotions, leave-in conditioners, root stimulators, perms/relaxers, dyes using...
Purpose Short-term reactions to BRCA1 and BRCA2 (BRCA1/2) genetic test results have been described in several reports, but the long-terms effects of testing not examined extensively. Methods We conducted an observational study characterize long-term impact for BRCA1/2 mutations 167 women who had received at least 4 years ago. also evaluated relationship between testing–specific breast ovarian cancer screening determine behavioral significance adverse reactions. Results Seventy-four percent...
Cervical cancer is the most commonly diagnosed and leading cause of mortality among women in sub-Saharan Africa. Recent recommendations for cervical primary prevention highlight HPV vaccination, secondary through screening. However, few studies have examined different dimensions health care access, how these may influence screening behavior, especially context clinical preventive services.Using 2003 South Africa World Health Survey, we determined prevalence with pelvic examinations and/or...
Maternal smoking in pregnancy (MSP) has been associated with DNA methylation specific CpG sites (CpGs) infants and children. We investigated whether MSP, independent of own personal active smoking, was midlife CpGs that were previously identified studies MSP-DNA used data on MSP collected from pregnant mothers 89 adult women born 1959–1964 measured blood (granulocytes) 2001–2007 (mean age: 43 years). Seventeen differentially methylated by multiple mapping to CYP1A1, MYO1G, AHRR, GFI1. These...
Importance Precision medicine is an approach to detecting, treating, and managing disease that based on individual variation in genetic, environmental, lifestyle factors. expected reduce health disparities, but this will be possible only if studies have adequate representation of racial minorities. Objective It critical anticipate the rates at which individuals from diverse populations are likely participate precision as research initiatives being developed. We evaluated likelihood...
The disproportionate use of chemical straighteners and skin lighteners by women color is a growing public health concern given the link between product adverse effects. Prior studies examined as an individual choice but neglected social-structural factors, which influence beauty perceptions personal decisions around use. We used community-based participatory research approach to characterize demographics investigated how racialized norms impact among 297 femme-identifying individuals in...
The impact of common environmental exposures in combinations with socioeconomic and lifestyle factors on cancer development, particularly for young adults, remains understudied. Here, we leveraged incidence data collected New York State at the county level to examine association between 31 10 cancers (i.e., lung bronchus, thyroid, colorectal, kidney renal pelvis, melanoma, non-Hodgkin lymphoma, leukemia both sexes; corpus uteri female breast cancer; prostate cancer), three age groups (25-49,...
Food insecurity (FI) is associated with several known hepatocellular carcinoma (HCC) risk factors, but few studies have directly examined FI in association HCC risk. We aimed to investigate whether county-level used data from 21 registries the Surveillance Epidemiology and End Results database obtain counts of cases 2018 2021. obtained rates for 2018–2021 Feeding America’s Map Meal Gap. multi-level Poisson regression models robust standard errors calculate incidence rate ratios (IRRs) 95%...
Alcohol consumption is associated with higher breast cancer risk. While studies suggest a modest association between alcohol intake and mammographic density, few have examined the in racial/ethnic minority populations.We assessed dense area total from digitized film mammograms an urban cohort of African American (42%), Caribbean (22%), white Hispanic (9%) women (n = 189, ages 40-61). We density (percent area). used linear regression to examine mean differences across categories. considered...
Despite the investments being made to develop biobanks, African Americans are under-represented in genomic studies. We identified factors having significant independent associations with intentions donate personal health information and blood and/or tissue samples a biobank national random sample of (n = 1,033).We conducted survey from October 2010 through February 2011.Twenty-three percent respondents reported that it was not at all likely they would biobank, 18% little likely, 36% somewhat...
Low rates of genetic counseling among African American women have generated concerns about disparities; however, to the extent that women's decisions accept or decline are consistent with their values, then lower participation may reflect preferences and not disparities. We evaluated which were satisfied decision participating in for BRCA1/2 mutations identified variables associated significantly satisfaction. Prospective study satisfaction 135 who had a minimum 5% prior probability having...
Removal or impairment of ovaries before menopause may affect a woman's breast cancer risk by altering her cumulative exposure to ovarian hormones. The Women's Contraceptive and Reproductive Experiences Study, population-based, multicenter case-control study incident invasive cancer, recruited women aged 35–64 years (4,490 cases 4,611 controls) who provided data on ovariectomy, hysterectomy, tubal sterilization during in-person interviews. Controls were frequency-matched age, race, site....
Full-term pregnancy (FTP) is associated with a reduced breast cancer (BC) risk over time, but women are at increased BC in the immediate years following an FTP. No large prospective studies, however, have examined whether number and timing of pregnancies for