A5088283814- Chronic Obstructive Pulmonary Disease (COPD) Research
- Obstructive Sleep Apnea Research
- Respiratory Support and Mechanisms
- Pediatric health and respiratory diseases
- Neuroscience of respiration and sleep
- Dysphagia Assessment and Management
- COVID-19 Clinical Research Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Respiratory and Cough-Related Research
- Non-Invasive Vital Sign Monitoring
- COVID-19 and healthcare impacts
- Neonatal Respiratory Health Research
- COVID-19 and Mental Health
- SARS-CoV-2 and COVID-19 Research
- Phosphodiesterase function and regulation
- Histone Deacetylase Inhibitors Research
- Asthma and respiratory diseases
- Healthcare cost, quality, practices
- Pulmonary Hypertension Research and Treatments
- Renal function and acid-base balance
- Pneumonia and Respiratory Infections
- Landscape and Cultural Studies
- Respiratory viral infections research
- COVID-19 diagnosis using AI
- Long-Term Effects of COVID-19
Union Hospital
2009-2025
Huazhong University of Science and Technology
2015-2025
Union Hospital
2010-2022
Wuhan Children's Hospital
2022
Wuhan Union Hospital
2011-2021
National Hellenic Research Foundation
2021
Chinese Academy of Sciences
2021
Center for Excellence in Molecular Cell Science
2021
University of Lübeck
2021
Örebro University
2021
<i>Background:</i> The Epworth Sleepiness Scale (ESS) is a questionnaire widely used in English speaking countries for assessment of subjective daytime sleepiness. <i>Objective:</i> Our purpose was to translate and validate the ESS use German-speaking countries. <i>Methods:</i> A German translation administered 159 healthy Swiss 174 patients with various sleep disorders. <i>Results:</i> mean ± SD scores normals 5.7 3.0, it 13.0 5.1 (p <...
Our purpose was to compare the effectiveness and side effects of a novel, single-piece mandibular advancement device (OSA-Monobloc) for sleep apnea therapy with those two-piece appliance lateral Herbst attachments (OSA-Herbst) as used in previous studies. An OSA-Monobloc an OSA-Herbst equal protrusion were fitted 24 obstructive patients unable use continuous positive airway pressure (CPAP) therapy. After adaptation period 156 +/- 14 d (mean SE), OSA-Monobloc, OSA-Herbst, no random order,...
To differentiate between respiratory infections caused by SARS-CoV-2 and other pathogens during the COVID-19 outbreak in Wuhan, we simultaneously tested for associated with CAP to determine incidence impact of coinfections patients.We included 250 patients who were diagnosed COVID-19. RT-PCR was used detect influenza A, B syncytial viruses. Chemiluminescence immunoassays IgM antibodies adenovirus, Chlamydia pneumoniae Mycoplasma serum patients. Based on these results, divided into two...
The 1-year mortality and health consequences of COVID-19 in cancer patients are relatively underexplored. In this multicenter cohort study, 166 with were compared 498 non-cancer non-COVID patients. all-cause hospital rates Cancer Cohort (30% 20%) significantly higher than those (9% 8%, both P < .001) (16% 2%, 0.001). 12-month post-discharge rate survival discharged (8%) was that (0.4%, but similar to (15%, = .084). incidence sequelae (23%, 26/114) is (30%, 130/432, .13). high among...
The efficient transmission of severe acute respiratory syndrome-2 coronavirus (SARS-CoV-2) from patients to health care workers or family members has been a worrisome and prominent feature the ongoing outbreak. On basis clinical practice in-vitro studies, we postulated that post-exposure prophylaxis (PEP) using Arbidol is associated with decreased infection among individuals exposed confirmed cases COVID-19 infection. We conducted retrospective cohort study on who were have SARS-CoV-2 by...
Th1/Th2 balances may play a vital role in the processes of inflammation and fibrosis. The paradigm can be evaluated by representing IFN-γ for Th1 IL-4 Th2. OM-85 BV encouraged preferential development Th1-type immunity characterized amplified decreased production. This study aimed to evaluate inhibitory effect OM85 on bleomycin (BLM)-induced pulmonary fibrosis C57 its possible mechanisms. In vitro experiments demonstrated that exhibited no significant toxicity HELF cells. inhibited...
Surgical lung volume reduction may improve pulmonary function and dyspnea in advanced emphysema. To investigate mechanisms of these beneficial effects we studied breathing patterns before after surgery. Nineteen patients with diffuse emphysema (FEV1 < 35% predicted, total capacity > 130% predicted) were within 1 mo before, 1.5 to 7 thoracoscopic reduction. Changes rib cage abdominal volumes monitored calibrated respiratory inductive plethysmography for 20 60 min during natural at rest....
The potential of respiratory inductive plethysmography (RIP) to detect inspiratory flow limitation during sleep was investigated. Sixteen apnoea patients underwent polysomnography. Airflow by a flowmeter attached nasal mask, oesophageal and mask pressure were recorded along with calibrated RIP. Presence defined constant or decreasing without dependence throughout significant portions inspiration, its absence linear mildly alinear pressure:airflow relationship. Based on this standard, three...
Background and purpose Early accurate diagnosis is vital in cerebral nocardiosis, a very rare infectious disease associated with high mortality rate. Herein, we report case that patient brain abscess was swiftly diagnosed successfully treated. Methods We of 61‐year‐old woman caused by Nocardia asiatica , combination Ziehl‐Neelsen staining metagenomics next‐generation sequencing (mNGS). Results A left breast cancer resection, diabetes mellitus 7‐month discontinuous cough fever admitted to our...
The well-known excessive daytime sleepiness (EDS) assessment, Epworth Sleepiness Scale (ESS), is not consistently qualified for patients with diverse living habits. This study aimed to build a modified ESS (mESS) and then verify its feasibility in the assessment of EDS suspected sleep-disordered breathing (SDB) central China. A Ten-item Questionnaire (10-ISQ) was built by adding two backup items original ESS. Then 10-ISQ administered 122 China SDB [among them, 119 cases met minimal...
Extended-spectrum β-lactamase (ESBL)-producing Escherichia coli (E. coli) and Klebsiella pneumoniae (K. pneumoniae) are the important pathogens causing pneumonia. This study aimed to investigate clinical characteristics molecular epidemiology of ESBL-producing E. K. pneumonia at a large teaching hospital in China.We collected patient's data strains (from December 2015 June 2016) Wuhan. The susceptibilities, multi-locus sequence typing, homologous analysis, ESBL genes by polymerase chain...
Hyperlactatemia may be caused by increased production due to tissue hypoxia or non-hypoxia. The aim of this study was first identify risk factors for postoperative hyperlactatemia (POHL) after Stanford type A acute aortic dissection surgery (AADS) and construct a predictive model, second evaluate the impact POHL on prognosis.This retrospective involved patients undergoing AADS from January 2016 December 2019 in Wuhan Union Hospital. Multivariate logistic regression analysis performed...
Abstract Background: To date, there is no effective medicine to treat coronavirus disease 2019 (COVID-19), and the antiviral efficacy of arbidol in treatment for COVID-19 remained equivocal controversial. The purpose this study was evaluate safety tablets COVID-19. Methods: This a prospective, open-label, controlled multicenter investigator-initiated trial involving adult patients with confirmed severe acute respiratory syndrome 2 (SARS-CoV-2) infection. Patients were stratified 1:2 either...
A large number of runaway electrons (REs) with energies as high several tens mega-electron volt (MeV) may be generated during disruptions on a large-scale tokamak. The kinetic energy carried by REs is eventually deposited the plasma-facing components, causing damage and posing threat operation remaining magnetic following thermal quench significant conversion to will increase first wall. dissipated inside vacuum vessel (VV) equals decrease initial VV plus flowing into disruption. Based...
Physical exercise effectively improves health-related quality of life in patients with chronic obstructive pulmonary disease (COPD). However, application this medical intervention is problematic, due to poor adherence the program or unawareness significance intervention.To determine whether COPD who adopted personal-preferred modalities (PPEMs) for daily training would demonstrate sustained benefits improved adherence.Stable were randomly assigned PPEMs group control (without extra apart...