- Consumer Perception and Purchasing Behavior
- Dementia and Cognitive Impairment Research
- Advanced Steganography and Watermarking Techniques
- Alzheimer's disease research and treatments
- Digital Rights Management and Security
- Cultural and Historical Studies
- Diverse Topics in Contemporary Research
- Healthcare Education and Workforce Issues
- Innovation in Digital Healthcare Systems
- Fashion and Cultural Textiles
- Digital Media Forensic Detection
- Education and Learning Interventions
- Functional Brain Connectivity Studies
- Job Satisfaction and Organizational Behavior
- Neurological Disease Mechanisms and Treatments
- Chaos-based Image/Signal Encryption
- Technology and Data Analysis
- Video Analysis and Summarization
- Cloud Data Security Solutions
- Customer Service Quality and Loyalty
- Health and Wellbeing Research
- Multimedia Communication and Technology
- Machine Learning in Healthcare
- Microbial Community Ecology and Physiology
- Schizophrenia research and treatment
Sungkyunkwan University
2018-2023
Samsung Medical Center
2018-2023
Chung-Ang University
2014-2023
Handong Global University
2017-2022
Kyung Hee University
2022
Korea University
2021
Midwestern University
2021
New York University
2021
Korea University Medical Center
2021
Korea Institute of Science and Technology
2018-2019
In Alzheimer's continuum (a comprehensive of preclinical disease [AD], mild cognitive impairment [MCI] due to AD, and AD dementia), dysfunctions are often related cortical atrophy in specific brain regions. The purpose this study was investigate the association between anatomical pattern neuropsychological deficits.A total 249 participants with (125 dementia, 103 MCI 21 AD) who were confirmed be positive for amyloid deposits collected from memory disorder clinic department neurology at...
The etching properties of C6F6/Ar/O2 in both an inductively coupled plasma (ICP) system and a capacitively (CCP) were evaluated to investigate the effects high C/F ratio perfluorocarbon (PFC) gas on etch characteristics SiO2. When SiO2 masked with ACL was etched C6F6, for CCP system, even though selectivity very (20 ~ infinite), due heavy-ion bombardment possibly caused by less dissociated high-mass ions from tapered profiles observed. In case ICP higher dissociation C6F6 O2 compared...
We investigated the frequency of β-amyloid (Aβ) positivity in 9 groups classified according to a combination 3 different cognition states and distinct levels white matter hyperintensities (WMH) (minimal, moderate, severe) aimed determine which factors were associated with Aβ after controlling for WMH vice versa.A total 1,047 individuals subjective cognitive decline (SCD, n = 294), mild impairment (MCI, 237), or dementia (n 516) who underwent PET scans recruited from memory clinic at Samsung...
Abstract Background A growing body of evidence shows differences in the prevalence cardiometabolic syndrome (CMS) and dementia based on gender ethnicity. However, there is a paucity information about ethnic- gender-specific CMS effects brain age. We investigated different age by Korean British cognitively unimpaired (CU) populations. also determined whether difference changes depending Methods These analyses used de-identified, cross-sectional data CU populations from Korea United Kingdom...
Abstract The authors identified factors affecting problem finding depending on degree of structure situation—either ill or moderately structured. Fifth-grade students (N = 115) were randomly assigned to 2 groups: Group 1 (n 60) accomplished the ill-structured task; 55) performed structured task. Results indicated that situation influenced variables finding. In situation, scientific knowledge and personality traits positively affected finding, divergent thinking negatively intrinsic...
ABSTRACT The transcription factor PpsR from the facultative photoheterotroph Rhodobacter sphaeroides is involved in repression of photosystem gene expression under aerobic growth conditions. We have isolated a number spontaneous mutations as well constructed directed and deletions ppsR . Repressor activities oligomeric state wild-type mutant proteins were assayed. Our results suggest that exists cell extracts tetramer. Analysis mutants confirmed carboxy-terminal region (residues 400 to 464)...
Amyloid positivity is an early indicator of Alzheimer's disease and necessary to determine the disease. In this study, a deep generative model utilized predict amyloid cognitively normal individuals using proxy measures, such as structural MRI scans, demographic variables, cognitive scores, instead invasive direct measurements. Through its remarkable efficacy in handling imperfect datasets caused by missing data or labels, imbalanced classes, outperforms previous studies widely used machine...
BACKGROUND Computerized versions of cognitive screening test could have advantages over pencil-and-paper by eliminating rater-dependent factors and saving the time required to score tests report results. We developed a computerized (Inbrain Cognitive Screening Test [Inbrain CST]) that takes about 30 minutes administer on touchscreen computer is composed neuropsychological already shown be sensitive in detecting early decline Alzheimer's disease (AD). The aims this study were 1) introduce...
In early 2020, the coronavirus 2019 (COVID-19) pandemic necessitated changes in social behavior to prevent its spread, including holding online classes, implementing distancing, and allowing employees telecommute. However, these have had a negative impact on people's sleep patterns mental health, particularly for college students.This study investigated relationship between health quality according lifestyle of students periods before after COVID-19.The subjects were 164 from Korea who both...
Abstract We developed machine learning (ML) algorithms to predict abnormal tau accumulation among patients with prodromal AD. recruited 64 AD using the Alzheimer’s Disease Neuroimaging Initiative (ADNI) dataset. Supervised ML approaches based on random forest (RF) and a gradient boosting (GBM) were used. The GBM resulted in an AUC of 0.61 (95% confidence interval [CI] 0.579–0.647) clinical data (age, sex, years education) higher 0.817 CI 0.804–0.830) neuropsychological data. highest was 0.86...
Abstract Background Cortical deposition of β-amyloid (Aβ) plaque is one the main hallmarks Alzheimer’s disease (AD). While Aβ positivity has been concern so far, predicting whether (−) individuals will convert to (+) become crucial in clinical and research aspects. In this study, we aimed develop a classifier that predicts conversion from using artificial intelligence. Methods Data were obtained Disease Neuroimaging Initiative (ADNI) cohort regarding patients who initially (−). We developed...
Amyloid-β (Aβ) evaluation in amnestic mild cognitive impairment (aMCI) patients is important for predicting conversion to Alzheimer's disease. However, Aβ through positron emission tomography (PET) limited due high cost and safety issues.We therefore aimed develop validate prediction models of positivity aMCI using optimal interpretable machine learning (ML) approaches utilizing multimodal markers.We recruited 529 from multiple centers who underwent PET. We trained ML algorithms a training...
Big Data brings new challenges to the field of e-Discovery or digital forensics and these are mostly connected various methods for data processing. Considering that most important factors time cost in determining success failure investigation, development a valid indexing method efficient search should come first more quickly accurately find relevant evidence from Data. This paper, therefore, introduces Distributed Text Processing System based on Hadoop called DTPS explains about...
This study identified factors that influenced fashion consumers' purchase intentions for cross-border online shopping. utilized three outshopping motivation dimensions (utilitarian, social, and hedonic) to empirically verify research questions. The moderating effects of perceived risks between shopping motivations behavioral intention were also tested on Korean female consumers in their 20s 40s who had experience purchasing goods through a channel within year. are as follows. First, the have...
Placental site trophoblastic tumor (PSTT) is the rarest form of gestational disease (GTD) and optimum management still controversial. In this study, we analyzed clinical features, treatment, outcomes 6 consecutive patients with PSTT treated in our institution.The electronic medical record database Samsung Medical Center was screened to identify from 1994 2017. records for details each patient's features treatment were extracted reviewed. This study approved Institutional Review Board...
To investigate the association between APOE genotype and β-amyloid (Aβ) burden, as measured by PET in patients with subcortical vascular cognitive impairment (SVCI) those Alzheimer disease-related (ADCI).This was a cross-sectional study of 310 SVCI 999 ADCI. evaluate effects or diagnostic group on Aβ positivity, we performed multivariate logistic regression analyses. Further distinctive underlying features latent subgroups were examined employing class cluster analysis approach.In comparison...
Abstract Amyloid-β(Aβ) PET positivity in patients with suspected cerebral amyloid angiopathy (CAA) MRI markers is predictive of a worse cognitive trajectory, and it provides insights into the underlying vascular pathology (CAA vs. hypertensive angiopathy) to facilitate prognostic prediction appropriate treatment decisions. In this study, we applied two interpretable machine learning algorithms, gradient boosting (GBM) random forest (RF), predict Aβ CAA markers. GBM algorithm, number lobar...
With the women's education level higher and gender equality more promoted, opportunity of taking part in business is increasing. Entering emotional age which counts self-image as being important, there a view that woman's appearance has direct relation to their social life. The research examine hypothesis important factors for women workers at banks successful career, is, verify effects appearances on life, furthermore, help female applicants bank clerks have desirable subjects were 200 male...
Abstract Recent improvements in neuroimaging and molecular markers of Alzheimer’s disease (AD) have aided diagnosis the early stage disease, which greatly increases chance for successful prevention treatment. However, expanding resources AD are unlikely to benefit all elderly due economic burden. Here, we aimed develop an inexpensive sensitive method detect early-stage AD. A scenario real-world social event memory test (SEMT) was created filmed 360° video. Participants watched 7-min video...
Abstract This study investigates the motivations to purchase luxury brands by examining how individual characteri-stics (need for uniqueness, self-monitoring, and vanity) influence affective brand attitudes pur-chase intentions through two social function (self-expression attitude self-presentation attitude)based on functional theory of attitudes. On-line surveys were implemented 314 consumers betweenthe ages 20 50 recruited. Using SPSS 18.0 AMOS 18.0, confirmatory factor analysis...