A5046898539- Sepsis Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Long-Term Effects of COVID-19
- Emergency and Acute Care Studies
- Intensive Care Unit Cognitive Disorders
- Appendicitis Diagnosis and Management
- Frailty in Older Adults
- COVID-19 and healthcare impacts
- Microscopic Colitis
- Intracerebral and Subarachnoid Hemorrhage Research
- Clostridium difficile and Clostridium perfringens research
- Clinical Reasoning and Diagnostic Skills
- Streptococcal Infections and Treatments
- Spinal Fractures and Fixation Techniques
- Diet and metabolism studies
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Health and Mental Health
- Diverticular Disease and Complications
- Cardiovascular Function and Risk Factors
- Blood Pressure and Hypertension Studies
- Neurosurgical Procedures and Complications
- Atrial Fibrillation Management and Outcomes
- Pancreatitis Pathology and Treatment
- Gastrointestinal disorders and treatments
Agostino Gemelli University Polyclinic
2018-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2018-2025
Università Cattolica del Sacro Cuore
2019-2025
Sapienza University of Rome
2005
Aim The aim of the present study was to describe clinical presentation patients aged ≥80 years with coronavirus disease 2019 (COVID‐19), and provide insights regarding prognostic factors risk stratification in this population. Methods This a single‐center, retrospective, observational study, carried out referral center for COVID‐19 central Italy. We reviewed records consecutively admitted confirmed over 1‐month period (1–31 March 2020). excluded asymptomatic discharged patients. identified...
To identify the most accurate early warning score (EWS) for predicting an adverse outcome in COVID-19 patients admitted to emergency department (ED).In adult consecutive (March 1-April 15, 2020) ED of a major referral centre COVID-19, we retrospectively calculated NEWS, NEWS2, NEWS-C, MEWS, qSOFA, and REMS from physiological variables measured on arrival. Sensitivity, specificity, positive (PPV) negative predictive value (NPV), area under receiver operating characteristic (AUROC) curve each...
Intensive Care Unit-Acquired Weakness (ICU-AW) is a common and severe complication in critically ill patients, characterized by profound often prolonged muscle weakness. The complexity of its diagnosis management requires multidimensional approach that integrates clinical, electrophysiological, imaging tools. This review focuses on the challenges diagnosing ICU-AW, emphasizing limitations traditional methods such as manual testing electrophysiological studies, highlights emerging role...
Background/Objectives Several scoring systems have been specifically developed for risk stratification in COVID‐19 patients. Design We compared, a cohort of confirmed older patients, three scores with previously established early warning score. Main endpoint was all causes in‐hospital death. Setting This is single‐center, retrospective observational study, conducted the Emergency Department (ED) an urban teaching hospital, referral center COVID‐19. Participants reviewed clinical records...
the role of microbes and chronic inflammation in pathogenesis Alzheimer' disease (AD) has been postulated by many authors. On other hand, several studies have reported main H. pylori infection and/or GUT microbiota alteration promoting inflammation, thus possibly influencing both occurrence evolution AD. In this article, we analyze most important recent performed on field humans animals provide possible pathogenic explanations.all animal, human, epidemiological in-silico studies, showed a...
Atherosclerotic cardiovascular disease (ASCVD) and venous thromboembolism (VTE) are severe complications of inflammatory bowel (IBD). Risk factors for ASCVD VTE in IBD not entirely elucidated. This study investigated the incidence risk compared to acute infective gastroenteritis colitis (AGC). We reviewed clinical records inpatients with AGC over 6 years. Each group's propensity score-matched (PS) subpopulation consisted 831 patients, ensuring a balanced comparison. Additionally, effect on...
Mental illnesses can have a significant impact on individuals experiencing acute coronary syndromes (ACS). are associated with an increased cardiovascular risk profile and early onset of disease. A critical aspect this interplay is the effect psychiatric conditions left ventricular ejection fraction (LVEF), key parameter in evaluating cardiac function predicting long-term outcomes ACS patients. The present single-center, retrospective study investigated associations between function, focus...
Background. Acute diarrhea is one of the leading causes Emergency Department (ED) access. The search for causative pathogen cannot be routinely performed since conventional methods, like stool cultures, are time-consuming, requiring days growth and delaying diagnosis start therapy. In this large sample retrospective study, we evaluated prognostic role serum procalcitonin (PCT) adult patients with acute in ED. Methods. a retrospective, mono-centric enrolled all visiting our ED complaining...
Introduction: Acute pancreatitis (AP) incidence in the elderly population has increased last years. However, role of age as influencing factor on AP clinical course is still debated. Methods: We reviewed records consecutive patients admitted with diagnosis AP. Patients were divided (≥65 years) and non-elderly (<65 years). Primary endpoint was comparison overall mortality. Secondary included ICU admission, in-hospital length stay (LOS) surgical procedures. Results: enrolled 352 532 patients....
Objectives: This study aimed to assess the effects of frailty and perceived quality life (QOL) on long-term survival (at least 1 year) patients ≥ 80 years hospitalized for COVID-19 predictors QOL deterioration in survivors. Design: is a single-center, prospective observational cohort study. Setting Participants: The was conducted teaching hospital enrolled all ≥80 old consecutively between April 2020 March 2021. Methods: Clinical variables assessed Emergency Department (ED), during...
Abstract While there is evidence of high use wide-spectrum antibiotics in children evaluated the pediatric emergency departments, determinants this behavior are still unclear. This study was aimed at defining demographic, social, clinical, and laboratory factors that affect antibiotic prescriptions discharged from department. We performed a retrospective observational aged younger than 18 years university hospital between Jan. 1, 2015 Dec. 31, 2020. determined proportion type prescription...
Background Infective endocarditis (IE) could be suspected in any febrile patients admitted to the emergency department (ED). This study was aimed at assessing clinical criteria predictive of IE and identifying prospectively validating a sensible easy-to-use prediction score for diagnosis ED. Methods Results We conducted retrospective observational study, enrolling consecutive with fever ED between January 2015 December 2019 subsequently hospitalized. Several anamnestic standardized variables...
Well recognized guidelines are available for the use of cranial computed tomography (CCT) in traumatic patients, while no definitely accepted standards exists to CCT patients without history head injury. The aim this study is propose an easy clinical score stratify need emergency department (ED) with suspect non-traumatic intracranial pathology. We retrospectively evaluated presenting ED neurological deficit, postural instability, acute headache, altered mental status, seizures, confusion,...