A5075418596- Urinary Bladder and Prostate Research
- Prostate Cancer Diagnosis and Treatment
- Pelvic floor disorders treatments
- Bladder and Urothelial Cancer Treatments
- Abdominal Surgery and Complications
- Urological Disorders and Treatments
- Thyroid and Parathyroid Surgery
- Urinary Tract Infections Management
- Minimally Invasive Surgical Techniques
- Pelvic and Acetabular Injuries
- Cardiac, Anesthesia and Surgical Outcomes
- Surgical Simulation and Training
- Hormonal and reproductive studies
- Anatomy and Medical Technology
- Renal cell carcinoma treatment
- Coronary Interventions and Diagnostics
- Surgical Sutures and Adhesives
- Venous Thromboembolism Diagnosis and Management
- Random lasers and scattering media
- Diagnosis and Treatment of Venous Diseases
- Immune cells in cancer
- Hemodynamic Monitoring and Therapy
- Antiplatelet Therapy and Cardiovascular Diseases
- Gut microbiota and health
- Hemostasis and retained surgical items
Kantonsspital Baden
2016-2025
Ludwig-Maximilians-Universität München
2020
University Hospital of Zurich
2010-2016
University of Zurich
2010-2016
Luzerner Kantonsspital
2010
Although malignant cells can be recognized and controlled by the immune system, in patients with clinically apparent cancer immunosurveillance has failed. To better understand local immunoregulatory processes that impact on progression, we correlated intratumoral immunological profiles survival of affected primary clear cell renal carcinoma (ccRCC). A retrospective analysis 54 ccRCC samples for 31 different response-related transcripts, revealed a negative correlation CD68 (a marker...
<i>Introduction:</i> Bipolar vessel-sealing devices (VSDs) have advantages in urological surgeries (less hemorrhage, shorter operating time). However, these instruments can cause thermal injuries, which result neural damage and necrosis. The objectives of this study were to establish a reproducible vitro model for standardized assessment electrosurgical evaluate whether optimized placement surgical reduce the spread. <i>Methods:</i> We evaluated spread two VSDs using...
To assess critical heat spread of cautery instruments used in robot-assisted laparoscopic (RAL) surgery.Thermal along bovine musculofascial tissues was examined by infrared camera, histology and enzyme assay. Currently monopolar, bipolar ultrasonic were investigated at various power settings application times. The efficacy using an additional Maryland clamp as a sink evaluated. A temperature 45 °C considered the threshold for possible nerve damage.Monopolar exhibited mean (sem) thermal 3.5...
Absorption of irrigation fluid was not detected during GreenLight™ laser vaporization the prostate using first generation 80 W laser. However, data are lacking on intraoperative absorption second 120 high power We assessed whether occurs prostate.We performed this prospective investigation at a tertiary referral center in patients undergoing for prostatic bladder outlet obstruction. Normal saline containing 1% ethanol used irrigation. The expired breath concentration measured periodically...
Purpose: To report a single surgeon experience with one year follow-up after open ureteroplasty buccal mucosa graft (OU-BMG) in the rare situation of long segment proximal ureteral strictures.Materials and Methods: Four patients stricture underwent OU-BMG between February July 2017.Functional outcome was assessed by pre-and postoperative serum creatinine, ultrasound renal scintigraphy as well patient reported outcomes.Results: an average length 4 cm 2017.No major complications...
To investigate if absorption of irrigation fluid occurs during bipolar plasma vaporisation (BPV) the prostate. examine clinical predictors increased risk and to assess changes in serum electrolytes, venous pH, haemoglobin or haematocrit are able detect intra-operative absorption.Over a 15-month period, 55 consecutive patients undergoing BPV prostate were investigated. The volume was measured using expired-breath ethanol measurements. Intra-operative performed with isotonic saline containing...
Technical modifications of the 120 W lithium-triborate laser have been implemented to increase power output, and prevent fiber degradation loss output during vaporization prostate. However, visible alterations at tip subjective impression decreasing ablative effectiveness indicate that delivering constantly high remains a relevant problem. Thus, we evaluated extent prostate.We investigated 46 fibers routine in 35 patients with prostatic bladder outflow obstruction. Laser beam was measured...
Withdrawal of oral antiplatelet therapy (OAT) is a major risk factor for stent thrombosis, myocardial infarction, and cerebral strokes. In order to minimize the thrombotic complications, since 2007 robotic-assisted laparoscopic radical prostatectomy (RARP) has taken place under continuous OAT with aspirin at our institution. this retrospective study we analyzed perioperative bleeding surgical outcome after RARP OAT.All patients who underwent institution were included in analysis. The group...
The transperitoneal approach (TP) and the retroperitoneal (RP) are two common methods for performing nephrectomy or partial nephrectomy. However, both approaches face difficulties, such as trocar placement limited working space (RP). TP is impaired in case of dorsal tumors dissection renal artery can be challenging due to anatomic localization dorsally vein. A hybrid that combines has been previously reported a series, but not evaluated systematically. This study proposes modified approach,...
Autologous cell transplantation for the treatment of muscle damage is envisioned to involve application precursor cells (MPCs) isolated from adult skeletal muscle. At onset trauma, these are recruited proliferate and rebuild injured fibres. However, a variety donor-specific cues may directly influence yield quality biopsy. In this study, we human MPCs assessed role donor gender age on ability form functional bioengineered We analysed yield, growth molecular expression in vitro, tissue...
To report outcomes of patients with localised prostate cancer (PCa) managed active surveillance (AS) in a standard clinical setting.Single-centre, prospective, observational study.Non-academic, average-size hospital Switzerland.Prospective, study at non-academic, Switzerland. Inclusion and progression criteria meet general recommendations. 157 median age 67 (61-70) years were included from December 1999 to March 2012. Follow-up (FU) ended June 2013.Median FU was 48 (30-84) months. Overall...
We report a case of transperineostomal bipolar resection the prostate (TPR-P) for lower urinary tract symptoms (LUTS). To our knowledge, this is first description in scientific literature. A 67-year-old man with medical history multiple penile debridements and formation perineostomy due to an episode severe Fournier's gangrene 2015, was admitted emergency room acute retention. Consecutively, suprapubic catheter inserted. Attempts catheterization failed bulbar stenosis obstructive prostatic...
Studies have shown that the human microbiome influences response to systemic immunotherapy. However, only scarce data exist on impact of urinary rates bladder cancer (BC) local Bacillus Calmette-Guérin instillation therapy. We launched prospective SILENT-EMPIRE study in 2022 address this question. report results pilot SILENT-EMPIRE, which aimed compare between fresh frozen (FF) and formalin-fixed paraffin-embedded (FFPE) samples cancerous tissue adjacent healthy BC patients. Our show alpha...
In this paper, we describe the development and evaluation of a novel tissue-holding device (THD) for use during robotic-assisted laparoscopic partial nephrectomy. The THD is vacuum-based apparatus made either 3D-printed polyethylene or stainless steel. proximal end connects to suction tubing routed outside body, while distal conically shaped designed firmly interface with tumor. Device feasibility studies were performed on six porcine kidneys, two livers, embalmed human cadavers. A...