Hailong Yuan

ORCID: 0000-0002-8469-9802
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Research Areas
  • Drug Solubulity and Delivery Systems
  • Advanced Drug Delivery Systems
  • Pharmacological Effects of Natural Compounds
  • Luminescence Properties of Advanced Materials
  • Advancements in Transdermal Drug Delivery
  • Natural product bioactivities and synthesis
  • Perovskite Materials and Applications
  • Drug Transport and Resistance Mechanisms
  • Advanced Photocatalysis Techniques
  • Drug-Induced Hepatotoxicity and Protection
  • Nanoparticle-Based Drug Delivery
  • Analytical Chemistry and Chromatography
  • MXene and MAX Phase Materials
  • Toxin Mechanisms and Immunotoxins
  • Advanced ceramic materials synthesis
  • Glass properties and applications
  • Phytochemistry and biological activity of medicinal plants
  • Bee Products Chemical Analysis
  • Heat Transfer and Boiling Studies
  • Metallurgical Processes and Thermodynamics
  • Luminescence and Fluorescent Materials
  • Phytochemical Studies and Bioactivities
  • Fluid Dynamics and Thin Films
  • Advanced Surface Polishing Techniques
  • Materials Engineering and Processing

Changchun University
2025

Air Force General Hospital PLA
2015-2024

Jiangxi University of Traditional Chinese Medicine
2021-2024

Air Force Medical University
2024

Foshan University
2023

South China University of Technology
2023

Beijing Microelectronics Technology Institute
2018-2023

Tianjin Chengjian University
2023

National Yang Ming Chiao Tung University
2023

Wuhan University of Technology
2017-2022

Abstract Near‐UV‐pumped white‐light‐emitting diodes with ultra‐high color rendering and decreased blue‐light emission is highly desirable. However, discovering a single‐phase white light emitter such characteristics remains challenging. Herein, we demonstrate that Mn doping as low 0.027 % in the hybrid post‐perovskite type (TDMP)PbBr 4 (TDMP= trans ‐2,5‐dimethylpiperaziniium) enables to achieve bright pure replicating spectrum of sun's rays. Thus, phosphor exhibiting an CIE coordinates...

10.1002/anie.201910180 article EN Angewandte Chemie International Edition 2019-12-12

In this study, self-discriminating hybrid nanocrystals was utilized to explore the biological fate of quercetin (QT-HNCs) with diameter around 280 nm (QT-HNCs-280) and 550 (QT-HNCs-550) following oral intravenous administration contribution integral bioavailability enhancement QT estimated by comparing absolute exposure QT-HNCs total in liver. Results showed that could reside vivo as intact for long 48 h administration. A higher accumulation liver lung observed both QT-HNCs. The particle...

10.1016/j.apsb.2021.02.015 article EN cc-by-nc-nd Acta Pharmaceutica Sinica B 2021-02-26

Paeoniflorin (Pae), a water-soluble monoterpene glucoside, has high potential clinical value in autoimmune and inflammatory diseases. However, the extremely low oral bioavailability of Pae (approximately 3%-4%) limits its formulation development application. This study aimed to develop micelles using glycyrrhizic acid (GL) as carrier improve absorption Pae.Pae-loaded GL were prepared by ultrasonic dispersion method was optimized single-factor tests. Characterizations Pae-loaded including...

10.1080/03639045.2020.1862178 article EN Drug Development and Industrial Pharmacy 2020-12-11

Abstract High‐temperature capacitors have become an important research topic recently as commercially available cannot fulfill the new requirements from industry. In this work, a ceramic ternary system (1 − x )[0.9Na 0.5 Bi TiO 3 ‐0.1BiAlO ]‐ NaNbO is introduced, and effects of concentration on macroscopic phase structure, locally disordered dielectric properties, conduction energy storage properties are studied. At optimum composition = 0.30, ultrawide temperature range (−90 320 °C)...

10.1002/aelm.201901429 article EN cc-by-nc Advanced Electronic Materials 2020-06-08

Background: Glycyrrhizic acid (GL), a pentacyclic triterpenoid glycoside, has been used as hepatoprotective agent for the treatment of acute and chronic hepatitis. However, its poor solubility permeability across gastrointestinal mucosa limit clinical efficacy. This study aimed to develop mixed micelles based on pluronic F127 d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) improve oral bioavailability GL.Methods: GL loaded F127/TPGS (GL-F127/TPGS-MMs) were prepared by thin film...

10.1080/03639045.2020.1775634 article EN Drug Development and Industrial Pharmacy 2020-05-28

Classical Be stars are rapidly rotating B-type exhibiting Balmer emission lines originating from circumstellar Keplerian gaseous disks, which likely form through episodic mass-ejection events. The currently favored model for star disks is the viscous decretion disk (VDD) model. However, mechanism behind mass ejection process during formation of a VDD mystery. We present peculiar behavior KIC 9715425, exhibited several minor outbursts (MIBs) and one major outburst (MAB) observed as...

10.1051/0004-6361/202452792 article EN cc-by Astronomy and Astrophysics 2025-01-14

The natural phenomenon of water vapor condensing on a cold surface is known as breath figures (BFs). growth process BFs solid and fluid surfaces has been thoroughly investigated to understand the mechanism BFs. It fascinating that ordered can be created volatile surfaces, highlighting significant influence BF growth. Currently, however, remains unclear ambiguous. Herein, an optical microscope was used observe in situ pure chloroform under static humid conditions. details obtained images were...

10.1063/5.0250311 article EN Physics of Fluids 2025-01-01

As AI technology continues to advance, the integration of and arts has become increasingly significant for countries aiming cultural powerhouses develop robust digital strategies. Modern enhances artistic creation, personalized experiences, accessibility. Therefore, it is necessary study how are currently being integrated. Utilizing text mining techniques, we analyze research papers on art in China Korea using ROST CM 6.0, identifying key trends differences. Our findings reveal that focuses...

10.1177/14727978251337903 article EN Journal of Computational Methods in Sciences and Engineering 2025-04-23

Glycyrrhizin (GL), extracted from the Glycyrrhiza glabra L., is active triterpenoid saponin components. However, due to its impermeability across gastrointestinal mucosa, oral bioavailability of drug was relatively low. To improve bioavailability, formulation GL as sodium deoxycholate/phospholipid-mixed nanomicelles (SDC/PL-MMs) has been performed in this study. GL-SDC/PL-MMs were produced by a film dispersion method and then investigated using photon correlation spectroscopy (PCS), zeta...

10.3109/1061186x.2012.702770 article EN Journal of drug targeting 2012-06-23

Cucurbitacin B (Cu B), a potent anti-cancer agent, suffers with the problems of water-insoluble, gastrointestinal side effects and non-specific toxicity via oral administration drawbacks in patient's compliance acceptance through injections. An integration nanoscale carriers mucoadhesive buccal films drug delivery system would resolve these issues effectively greater therapeutic benefits clinical significance. Thus, loaded film was developed characterized this study carboxymethyl chitosan...

10.3109/10717544.2013.876459 article EN Drug Delivery 2014-01-27

Objective: The purpose of this study was to design and optimize a novel drug nanoparticles-loaded oral fast dissolving film (NP-OFDF) using Box–Behnken design–response surface methodology.Methods: Drug nanosuspensions produced from high pressure homogenization were transformed into containing nanoparticles by casting methods. Herpetrione (HPE), potent antiviral agent with poor water solubility that extracted Herpetospermum caudigerum, studied as the model drug. formulations HPE (HPE-NP-OFDF)...

10.3109/03639045.2014.884116 article EN Drug Development and Industrial Pharmacy 2014-02-10

The purpose of this study was to design novel drug nanocrystals (NCs) stabilized by glycyrrhizic acid (GL) for achieving liver targeted delivery due the presence GL receptor in hepatocytes. Quercetin (QT) exhibits good pharmacological activities treatment diseases, including steatosis, fatty hepatitis, fibrosis, and cancer. It selected as a model owing its poor water solubility. QT NCs (QT-NCs/GL) were fabricated wet media milling technique systemically evaluated. QT-NCs poloxamer 188...

10.1016/j.ijpx.2024.100246 article EN cc-by-nc-nd International Journal of Pharmaceutics X 2024-04-09

The aim of this study was to develop hyperoside (Hyp) nanocrystals enhance its dissolution rate, oral bioavailability and anti-HBV activity. Hyp were prepared using high pressure homogenization technique followed by lyophilization. A Box–Behnken design approach employed for process optimization. physicochemical properties, pharmacokinetics activity in vivo nanocrystal with the optimized formulation systematically investigated. found be rod shaped particle size 384 ± 21 nm PDI 0.172 0.027....

10.3109/03639045.2016.1173051 article EN Drug Development and Industrial Pharmacy 2016-04-01
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