- Musculoskeletal pain and rehabilitation
- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Cardiac Imaging and Diagnostics
- Complex Network Analysis Techniques
- Bacterial Identification and Susceptibility Testing
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Cardiac Valve Diseases and Treatments
- Antibiotic Resistance in Bacteria
- Infective Endocarditis Diagnosis and Management
- Sports injuries and prevention
- Antimicrobial Resistance in Staphylococcus
- Atrial Fibrillation Management and Outcomes
- Clostridium difficile and Clostridium perfringens research
- Advanced X-ray and CT Imaging
- Opinion Dynamics and Social Influence
- Lung Cancer Treatments and Mutations
- Spine and Intervertebral Disc Pathology
- Human Mobility and Location-Based Analysis
- Flexible and Reconfigurable Manufacturing Systems
- Transportation Planning and Optimization
- Radiation Dose and Imaging
- Aortic Disease and Treatment Approaches
- Bacterial biofilms and quorum sensing
- Advanced MRI Techniques and Applications
Ludwig-Maximilians-Universität München
2018-2025
LMU Klinikum
2025
University of Freiburg
2002-2024
Asklepios Fachkliniken München-Gauting
2023-2024
German Center for Infection Research
2016-2023
University Medical Center Freiburg
2007-2023
German Center for Lung Research
2018-2023
University of Basel
2023
University Children’s Hospital Basel
2023
Schön Klinik München Harlaching
2012-2022
Human mobility is differentiated by time scales. While the mechanism for long scales has been studied, underlying on daily scale still unrevealed. Here, we uncover responsible patterns analysing temporal and spatial trajectories of thousands persons as individual networks. Using concept motifs from network theory, find only 17 unique networks are present in they follow simple rules. These networks, called here motifs, sufficient to capture up 90 per cent population surveys mobile phone...
PURPOSE: To evaluate the safety and feasibility of magnetic resonance (MR) imaging at 0.5 T in patients with implanted cardiac pacemakers. MATERIALS AND METHODS: Twenty-one models pacemakers 44 pacemaker electrodes were exposed to vitro MR continuous registration output temperature lead tip. Prior examination, programmed an asynchronous mode (A00, V00, or D00). Pacemakers examined before after imaging. Forty-four underwent 51 examinations under cardiologic surveillance, electrocardiography,...
The objectives of this study were to prospectively assess the rectal carriage rate third-generation cephalosporin-resistant Enterobacteriaceae (3GCREB) in non-ICU patients on hospital admission and investigate resistance mechanisms risk factors for carriage. Adult screened 3GCREB at six German tertiary care hospitals 2014 using swabs or stool samples. isolates characterized by phenotypic molecular methods. Each patient answered a questionnaire about potential colonization with MDR organisms...
We assessed the capacity of three DNA typing techniques to discriminate between 81 geographically, temporally, and epidemiologically unrelated strains Pseudomonas aeruginosa. The methods, representing powerful tools for hospital molecular epidemiology, included hybridization restricted chromosomal with toxA genes coding rRNA (rDNA) used as probes macrorestriction analysis SpeI-digested by pulsed-field gel electrophoresis. probe were able classify all into a limited number types,...
Sternal wound complications following median sternotomy remain a challenge in cardiac surgery. Changes both patient profile and type of operations have been observed recent years. Therefore, we analysed current healing after at our centre.All adult patients undergoing between January 2009 April 2011 were included this retrospective analysis. Transplants assist devices implantations omitted. We assessed outcome, prognostic factors microbiological results standardized swabs.In total, 1297 with...
Lactobacillus represents a large genus with different implications for the human host. Specific lactobacilli are considered to maintain vaginal health and protect from urogenital infection. The presence of species in carious lesions on other hand is associated progressive caries. Despite their clinical significance, species-level identification still poses difficulties mostly involves combination phenotypic genotypic methods. This study evaluated rapid MALDI-TOF MS analysis oral isolates...
This paper is summarizing and comparing properties of channel models used for Beyond-3G (B3G) MIMO simulations: 3GPP spatial model (SCM), its extension (SCME), developed by WINNER. Compared are offering complete description in a sense large-scale as well small-scale effects radio-channel. WINNER targeted was supposed to provide reliable tool estimation system performance, covering frequencies up 5 GHz bandwidths 100 MHz different types environment. Since SCM originally proposed 2 range...
The self-similarity of complex networks is typically investigated through computational algorithms, the primary task which to cover structure with a minimal number boxes. Here we introduce box-covering algorithm that outperforms previous ones in most cases. For two benchmark cases tested, namely, E. coli and World Wide Web (WWW) networks, our results show improvement can be rather substantial, reaching up 15% case WWW network.
While medulloblastoma was initially thought to comprise a single homogeneous entity, it is now accepted that in fact comprises 4 discrete subgroups, each with its own distinct demographics, clinical presentation, transcriptomics, genetics, and outcome. Hydrocephalus common complication of not infrequently requires CSF diversion. The authors report the incidence diversion surgery subgroups (Wnt, Shh, Group 3, 4).The medical imaging records for patients who underwent at Hospital Sick Children...
Abstract The appearance of large geolocated communication datasets has recently increased our understanding how social networks relate to their physical space. However, many recurrently reported properties, such as the spatial clustering network communities, have not yet been systematically tested at different scales. In this work we analyze structure over 25 million phone users from three countries scales: country, provinces and cities. We consistently find that last urban scenario presents...
Abstract Objectives To assess the admission prevalence of third-generation cephalosporin-resistant Enterobacterales (3GCREB) and to whether risk factors vary by β-lactamase genotype. Methods Adult patients were recruited within 72 h general wards six university hospitals in 2014 2015. Rectal swabs screened for 3GCREB isolates analysed phenotypically genotypically. Patients questioned on potential factors. Multivariable analyses performed identify colonization specific β-lactamases. Results...
Low-to-moderate quality meta-analytic evidence shows that motor control stabilisation exercise (MCE) is an effective treatment of non-specific low back pain. A possible approach to overcome the weaknesses traditional meta-analyses would be a prospective meta-analyses. The aim present analysis was generate high-quality support view exercises lead reduction in pain intensity and disability patients when compared group. In this meta-analysis sensitivity multilevel meta-regression within...
ObjectiveTo identify predictors of adherence in supervised and self-administered exercise interventions for individuals with low back pain.DesignCohort study.SettingRehabilitation.ParticipantsThis pre-planned re-analysis within the MiSpEx Network included 1,511 participants pain (57% female, mean age 40.9 years, SD ±14 years).InterventionsParticipants underwent an initial 3-week phase sensorimotor exercises, followed by a 9-week phase.Main Outcome MeasuresBiological, psychological, social...
BackgroundDocetaxel alone or in combination with ramucirumab nintedanib is recommended as second-line treatment metastatic non-small cell lung cancer (NSCLC) patients after progression on first-line platinum-base chemotherapy immune-checkpoint inhibitors (ICI). The purpose of our study was to compare the toxicity profile and efficacy docetaxel paclitaxel- pemetrexed-platinum ICI.Patients und MethodsMetastatic NSCLC treated pemetrexed paclitaxel-platinum without ICI were included...
To evaluate the impact of an intervention to reduce duration antibiotic treatment for pneumonia in a neurosurgical intensive care unit (ICU). The usage antibiotics and resultant costs were examined using interrupted time series analysis while resistance device-associated infection rates are also described.In January 2004, revised guidelines use implemented. As consequence this, therapy nosocomial was reduced from 14 7 days, community-acquired period fell 10 5 days. effect on density [AD;...
There are limited data on adverse drug event rates in pediatrics. The authors describe the implementation and evaluation of an automated surveillance system modified to detect events (ADEs) pediatric patients. constructed screen admissions a large hospital. Potential ADEs identified by were reviewed medication safety pharmacists physician scored for causality severity. Over 6 month study period, 6,889 children admitted hospital total 40,250 patient-days. ADE generated 1226 alerts, which...