A5063821259- Head and Neck Surgical Oncology
- Sinusitis and nasal conditions
- Oral and Maxillofacial Pathology
- Craniofacial Disorders and Treatments
- Bone Tumor Diagnosis and Treatments
- Esophageal Cancer Research and Treatment
- Metabolism, Diabetes, and Cancer
- Salivary Gland Tumors Diagnosis and Treatment
- Endoplasmic Reticulum Stress and Disease
- Cleft Lip and Palate Research
- Cancer, Hypoxia, and Metabolism
- Pediatric health and respiratory diseases
- Cerebrospinal fluid and hydrocephalus
- Medical Research and Treatments
- Nasal Surgery and Airway Studies
- Brain Metastases and Treatment
- Ear and Head Tumors
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
Anhui Provincial Hospital
2025
Anhui Medical University
2025
Beijing Tongren Hospital
2016-2024
Capital Medical University
2016-2024
The well-known insulin-like growth factor 1 (IGF1)/IGF-1 receptor (IGF-1R) signaling pathway is overexpressed in many tumors, and thus an attractive target for cancer treatment. However, results have often been disappointing due to crosstalk with other signals. Here, we report that IGF-1R stimulates the of hepatocellular carcinoma (HCC) cells through translocation into ER enhance sarco-endoplasmic reticulum calcium ATPase 2 (SERCA2) activity. In response ligand binding, IGF-1Rβ translocated...
Objective:A retrospective study aimed to investigate the characteristics and prognosis of inflammatory sphenoid sinus diseases discuss endoscopic surgical techniques.Method:A total 105 subjects with isolated pathologies were treated by surgery,which included 41(39.0%) cases fungal sinusitis,33(31.4%) mucocele,and 31(29.5%) sphenoiditis.They evaluated paranasalsinuse CT scan all patients underwent sphenoidsinus surgery under general anesthesia.Twenty selected in Messerklinger,74 Wingand,5...
To investigate the efficacy and safety of endoscopic resection infratemporal fossa mass to determine indications for surgery.
Objective: To analyze the efficacy of endoscopic surgery for frontal sinus meningoencephalocele and cerebrospinal fluid (CSF) leaks, to explore surgical strategy. Methods: A total 35 patients with CSF leaks who underwent transnasal at Beijing Tongren Hospital, Capital Medical University between May 2007 December 2023 were enrolled in this retrospective case series, including 29 males 6 females, age (35.23±15.76) years. High-resolution CT magnetic resonance cisternography undertaken before...
Objective: To evaluate the efficacy of neoadjuvant chemotherapy (NACT) in treatment locally advanced olfactory neuroblastoma (ONB), and to explore factors related NACT. Methods: A total 25 patients with ONB who underwent NACT Beijing TongRen Hospital from April 2017 July 2022 were retrospectively analyzed. There 16 males 9 females, an average age 44.9 years (ranged 26-72 years). 22 cases Kadish stage C 3 D. After multiple disciplinary team(MDT) discussion, all treated sequentially...
Objective: To analyze the dynamic changes of clinical features chronic rhinosinusitis in recent 10 years, so as to deeply understand characteristics rhinosinusitis, and provide new ideas for treatment rhinosinusitis. Method: This retrospective study was performed patients who were diagnosed enrolled. General information, examination pathological results all collected, then patients' age, gender, incidence asthma allergic rhinitis, peripheral eosinophil percentage, olfactory dysfunction...
Objective: To analyze the imaging features of unilateral maxillary sinus nasal lesions and selection treatment strategies based on findings for these lesions. Method: The CT enhanced MRI data 64 cases were selected. surgery approach observed recorded. summarize characteristics choice strategy. Result: All Unilateral presented a roughly uniform soft tissue density shadow CT. In all benign lesions, there 9 manifested wall bone destruction discontinuity(18.4%,9/49); There 17 hyperplasia...
Objective:To explore the clinical effects, surgical procedure and indications of treatment for benign lesions in maxillary sinus through modified prelacrimal duct recess approach. Method:All 21 patients this study who diagnosed with sinus, received routine preoperational exam underwent endoscopic surgery Postoperatively medical treatment, regular follow-up average 11.3 months(from 3 months to 16 months). Result:Among patients, there were 9 cases cyst, 6 choanal polyps, 5 hemorrhagic necrotic...
Objective: To summarize the follow-up outcomes of frontal drill out procedures (draf Ⅱb, extended draf Ⅱb and Ⅲ) using mucosal flaps, discuss surgical indications different flaps their potential benefits to opening neo-ostium. Methods: A total 48 patients with chronic rhinosinusitis or mucoceles treated by Ⅲ between 2013 2019 in Beijing TongRen Hospital were enrolled this study. Twenty-four who considered as flap group (including 19 males 5 females, aging from 71 years), other 24 didn't have...