A5037949594- Sinusitis and nasal conditions
- Head and Neck Surgical Oncology
- Nasal Surgery and Airway Studies
- Oral and Maxillofacial Pathology
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Smoking Behavior and Cessation
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Infectious Diseases and Mycology
- Bone Tumor Diagnosis and Treatments
- Meningioma and schwannoma management
- COVID-19 and Mental Health
- Air Quality and Health Impacts
- Obesity, Physical Activity, Diet
- Cerebrospinal fluid and hydrocephalus
- Olfactory and Sensory Function Studies
- RNA modifications and cancer
- Actinomycetales infections and treatment
- Cleft Lip and Palate Research
- Teratomas and Epidermoid Cysts
- Ecology and Conservation Studies
- Global Public Health Policies and Epidemiology
- Pediatric health and respiratory diseases
- Cardiovascular Health and Risk Factors
China-Japan Friendship Hospital
2023-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2025
Tobacco Research Institute
2025
Beijing Tongren Hospital
2015-2024
Capital Medical University
2015-2024
National Clinical Research
2024
Academy of Medical Sciences
2024
Peking Union Medical College Hospital
2023-2024
State Council of the People's Republic of China
2023
Ministry of Education of the People's Republic of China
2023
Empty nose syndrome (ENS) is considered an acquired condition that remains difficult to diagnose objectively. Defining specific symptoms can be reliably associated with this disorder would essential identifying possible ENS patients. We sought validate ENS-specific, 6-item questionnaire as adjunct the standard Sino-Nasal Outcome Test 22 (SNOT-22) discriminate patients suspected of having ENS.The Nose Syndrome Questionnaire (ENS6Q) paired 6 common (nasal suffocation, nasal burning, openness,...
Background The intranasal endoscopic prelacrimal recess approach (PLRA) access to all aspects of the maxillary sinus while preserving inferior turbinate and nasolacrimal duct its use have been reported in treatment many lateral skull base diseases. Objective To retrospectively assess effectiveness a 10-year multicenter follow-up for resection inverted papilloma (IPMS) via PLRA. Methods A total 71 patients were admitted underwent IPMS excision an PLRA from 2003 2013. All high-resolution...
The prevalence of cigarette smoking among women is significantly different from that men, however, use by little known. study aims to describe and patterns Chinese females age province.
To our knowledge, there is no available nationwide data on omicron symptom patterns in China mainland. We aim to determine the acute and long COVID-19 symptoms omicron-dominant period evaluate its association with risk factors. designed a cross-sectional study about self-reported were collected by an online platform named Wenjuanxing. Eligible participants aged 25–65 years symptomatic. In this study, ratios of number people different ages genders weighted from Seventh National Census (2020...
Background: Cigar smoking poses significant public health challenges due to its rising prevalence and associated risks. However, research on cigar use in China remains limited. This study investigates the prevalence, demographic characteristics, key factors with among Chinese adults. Methods: We analyzed data from 2018–2019 Health Literacy Survey, including 86,701 participants aged 20–69 years. Multistage stratified sampling was employed, logistic regression used estimate odds ratios (ORs)...
This consensus will introduce the characteristics of fillers used in surgical cavities domestic nasal surgery patients based on relevant literature and expert opinions. It also provide recommendations for selection cavity different diseases, with chronic sinusitis as a representative example.
Neo-osteogenesis of the paranasal sinuses is a radiologic finding unclear clinical significance. Although current evidence suggests that these bony changes represent an inflammatory response rather than infectious osteitis, bacteria associated with sinonasal mucosa may induce mediators as mechanism neo-osteogenesis. The objectives this study were (1) to determine whether there association between isolated on sinus culture and neo-osteogenesis, (2) identify other predictive factors for...
Stenosis of the frontal neo-ostium after Draf III procedure has been associated with inflammatory risk factors. However, degree to which neo-osteogenesis contributes postsurgical stenosis is unclear.Twenty-five patients chronic sinusitis who underwent and had followed for at least 12 months were included. Paranasal sinus computed tomography (CT) scans performed 7 days 1 year postoperatively. The cross-sectional area amount measured by a standardized protocol using triplanar radiologic...
Background Chronic rhinosinusitis (CRS) without nasal polyps (CRSsNP) and with (CRSwNP) is reported to involve different inflammatory processes in sinonasal mucosa bone tissue, these remain uncharacterized. Objective We aimed investigate the molecular mechanisms of osteitis Chinese patients CRS better understand pathogenesis CRS. Methods The study included 10 controls, 16 CRSsNP, 23 CRSwNP. Ethmoid tissue samples were evaluated by histologic examination. Quantitative real-time reverse...
We describe the surgical technique for use of small intestine submucosal (SIS) xenograft implant inferior turbinate reconstruction and report our early results in a pilot case series patients suffering from symptoms consistent with empty nose syndrome (ENS).We an observational prospective cohort study ENS undergoing using porcine SIS xenograft. Effects procedure on quality life (QOL) were assessed through serial 25-item Sino-Nasal Outcome Test (SNOT-25) scores analyzed by 1-way analysis...
The aim of this study was to compare the efficacy bioabsorbable steroid-eluting sinus stents versus absorbable Nasopore packs after endoscopic surgery (ESS) for treatment chronic rhinosinusitis (CRS).One hundred eighty-one patients with CRS who underwent ESS were randomly assigned receive a stent in one ethmoid cavity, whereas contralateral control side received pack. Endoscopic evaluations performed 14, 30, and 90 days ESS. Postoperative intervention, polyp formation, adhesions, middle...
Analysis of recent research indicated that T-helper cells may play an important role in the pathogenesis chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and CRS without (CRSsNP).The purpose this study was to investigate peripheral blood Th1 Th2 eosinophil population patients CRS.Peripheral samples were obtained from nine nonatopic controls, 37 CRSsNP, 66 CRSwNP. The then analyzed by flow cytometry analysis (Th1 cell [CD4+, interleukin 4-, interferon γ+]; 4+, γ-]). stratified into...
Our understanding of empty nose syndrome (ENS) continues to evolve. Prior studies evaluating airway augmentation treat ENS did not use validated disease‐specific questionnaires, making the true impact these surgeries unclear. We present a case series 10 patients with (11 procedures) who underwent inferior meatus procedure (IMAP) between September 2014 and May 2017. Subjective outcomes IMAP included comparisons preoperative postoperative assessments (1 week, 1 month, 3 months, 6 months) using...
Objective The aim of this study is to provide histopathological evidence for a better understanding the excision bone underlying tumor. Study Design Retrospective study. Methods Thirty patients with diagnosis sinonasal inverted papilloma (SIP) were enrolled. All underwent preoperative radiography define tumor location. primary and bone, removed during endoscopic surgery, examined under microscope. Results Twenty‐five 30 specimens exhibited bony hyperostosis on computed tomography (CT)...
Background The aim of this work was to present our single‐center experience on orbital cavernous hemangiomas managed using an endonasal endoscopic approach. Methods study design used one‐institutional retrospective review. Twenty‐three cases hemangioma were analyzed and followed up. Results There 10 males 13 females, with average age 46.1 years, included in study. Seven extraconal, 16 intraconal, the patients optic nerve involved compressed. Total resection tumor achieved cases; remaining 7...
MicroRNAs can function as tumor suppressor miRNAs. Bcl-2 is an antiapoptotic gene overexpressed in many tumors, including nasopharyngeal carcinoma (NPC). It reported that microRNA-15a (miR-15a) and microRNA-16-1 (miR-16-1) could act bcl-2 inhibitors. To investigate their effects on NPC, the authors used recombinant lentiviral vector to upregulate expression of miR-15a/16-1 NPC CNE-2Z cells. The divided cells into control group, transfection radiotherapy transfection-radiotherapy group. In...
<b><i>Objectives:</i></b> To identify the optimal cutoff value in Hounsfield units (HU) of maxillary sinus (MS) opacity and bone thickness (neo-osteogenesis) MS as radiological predictors for mycetoma. <b><i>Methods:</i></b> One hundred sixty-four patients, including 59 patients with unilateral mycetoma, 31 odontogenic sinusitis, 44 chronic rhinosinusitis 30 rhinitis, who underwent or turbinate surgery were recruited. The thickness, HU...
Conclusions: There is clear correspondence between HU and histopathological evaluation of osteitis. It feasible to evaluate bone remodeling in rabbit models with rhinosinusitis by measuring the HU.Objective: The objective this study was determine whether HUs CRS can be used objectively degree osteitis.Methods: Sixty were inoculated staphylococcus aureus. rabbits divided into three groups. Each group a medication administration team control team. each image measured. All animals executed...
<b><i>Background/Aims:</i></b> This study aimed to determine the dynamic change of postoperative T-helper cell cytokines in nasal secretions and serum chronic rhinosinusitis with polyps (CRSwNP). <b><i>Methods:</i></b> Nasal samples 30 CRSwNP patients 10 healthy subjects were collected. Among patients, collected 1 day before endoscopic sinus surgery (ESS) that 18 (12 asthmatic 6 non-asthmatic) 4, 8, 12 weeks after ESS. Concentrations...
Background The Draf 3 procedure has been demonstrated to be effective in the treatment of refractory frontal sinus disease. A variety clinical factors may contribute change neo-ostium (FNO) area after this procedure. Imaging plays a vital role evaluation and follow-up surgery provides useful prognostic information. Objectives (1) To investigate influence local anatomic on FNO by radiological measurements imaging software (2) explore other predictive restenosis. Methods Twenty-four patients...