A5068191577- Birth, Development, and Health
- Pancreatic function and diabetes
- Diet and metabolism studies
- Diet, Metabolism, and Disease
- Adipose Tissue and Metabolism
- Regulation of Appetite and Obesity
- Metabolism, Diabetes, and Cancer
- Diabetes and associated disorders
- Folate and B Vitamins Research
- Fatty Acid Research and Health
- Aquaculture Nutrition and Growth
- MicroRNA in disease regulation
- Phytoestrogen effects and research
- Indigenous Health and Education
- Nutrition and Health in Aging
- Biochemical effects in animals
- Obesity, Physical Activity, Diet
- Magnesium in Health and Disease
- Muscle metabolism and nutrition
- Aldose Reductase and Taurine
- Child Nutrition and Water Access
- Exercise and Physiological Responses
- Pregnancy and preeclampsia studies
- Liver Disease Diagnosis and Treatment
- Gestational Diabetes Research and Management
Universidade Federal de Mato Grosso
2013-2024
New York University Press
2013
Cambridge University Press
2013
Universidade Estadual Paulista (Unesp)
2011
Food & Nutrition
2008
Secretaria da Saúde
2005
Universidade Estadual de Campinas (UNICAMP)
1998
We studied glucose homeostasis in rat pups from dams fed on a normal-protein (170 g/kg) (NP) diet or containing 60 g protein/kg (LP) during fetal life and the suckling period. At birth, total serum protein, albumin insulin levels were similar both groups. However, body weight LP rats lower than those NP rats. end of period (28 d age), significantly liver glycogen free fatty acid higher compared with Although fasting level was groups, area under blood concentration curve after load for (859 (...
Some metabolic alterations were evaluated in Wistar rats which received control or low-protein (17%; 6%) diets, from the pregnancy until end of lactation: non-lactating (CNL), lactating (CL), (LPNL) and (LPL) groups. Despite increased food intake by LPL dams, both LP groups reduced protein final body mass was lower LPL. Higher serum glucose occurred Lactation induced insulin glucagon levels, but these diet. Prolactin levels rose lactating, impaired LPL, followed losses mammary gland (MAG)...
Excess of glucocorticoids (GCs) during pregnancy is strongly associated with the programming glucose intolerance in offspring. However, impact high GC levels on maternal metabolism not clearly documented. This study aimed to test hypothesis that mothers exposed elevated GCs might also display long-term disturbances homeostasis. Dexamethasone (DEX) was administered noninvasively via drinking water between 14th and 19th days pregnancy. Mothers were subjected insulin tolerance tests at 1, 2, 3,...
Objectives: We investigated the influence of leucine supplementation on insulin secretion and some proteins related to in malnourished mice. Methods: Swiss mice (aged 21 days) received isocaloric normo-17% (NP) or 6% low-protein (LP) diet for 120 days. Half NP LP 1.5% drinking water during last 30 days (NPL LPL, respectively). Results: The were hypoinsulinemic compared with group, whereas LPL exhibited increased insulinemia fed state versus mouse islets less responsive 22.2 mM glucose, 100...
The World Health Organization recommends exclusive breastfeeding until 6 months of age as an important strategy to reduce child morbidity and mortality. Studies have associated early weaning with the development obesity type 2 diabetes in adulthood. In our model, we demonstrated that leads increased insulin secretion adolescent males reduced adult offspring. Early weaned exhibit resistance skeletal muscle. did not change signalling muscle female Taking into account is one primary factors for...
AIM: The aim of this study was to evaluate the effect probiotics on recovery bowel atrophy induced by malnutrition in rats. METHODS: Twenty-and-six Wistar rats (200-250g) were fed with either a normoproteic (sha... | Find, read and cite all research you need Tech Science Press
In pancreatic islets, glucose metabolism is a key process for insulin secretion, and pregnancy requires an increase in secretion to compensate the typical resistance at end of this period. Because low‐protein diet decreases type could impair homeostasis, leading gestational diabetes. we investigated GLUT2, glucokinase hexokinase expression patterns as well uptake, utilization oxidation rates. Adult control non‐pregnant (CNP) pregnant (CP) rats were fed normal protein (17%), whereas (LPNP)...
Fat mass and obesity-related (FTO) gene single nucleotide polymorphisms (SNPs) interferes with food preferences that impact macronutrient intake. Few studies have investigated the relationship of this intake micronutrients. Moreover, shown multiple micronutrient deficiencies in patients obesity. This work evaluated effect FTO rs9939609 polymorphism on dietary nutritional quality macronutrients vitamins women obesity candidates for metabolic surgery. The study included 106 (24 to 60 years...
Previous studies in our laboratory have demonstrated that the treatment of diabetic rats during 21 days with V. macrocarpa stem-bark ethanolic extract (VmE), reduced glycemia, urinary glucose and urea, increased liver glycogen content improved other parameters diabetes related. The objective this study was to evaluate if anti-hyperglycemic mechanisms VmE could be caused by improvement insulin signaling pathway peripheral tissues (liver, adipose skeletal muscle).Streptozotocin-diabetic were...
We investigated if alterations in the insulin-signaling pathway could contribute to reduced hepatic glycogen levels adult rats subjected a protein deficiency during intrauterine life and lactation reared through recovery on soybean diet.Rats from mothers fed with 17% or 6% (casein) pregnancy were maintained casein diet (offspring born suckled by control subsequently same after weaning [CC group] offspring flour [CS group]), of low-protein [LC containing [LS [LL group]) until 90 d life.A did...
Malnutrition in early life impairs glucose-stimulated insulin secretion adulthood. Conversely, pregnancy is associated with a significant increase under conditions of normoglycaemia. A failure β-cell adaptive changes may contribute to the onset diabetes. Thus, glucose homeostasis and function were evaluated control-fed pregnant (CP) non-pregnant (CNP) or protein-restricted (LPP) (LPNP) rats, from fetal adult life, rats that recovered after weaning (RP RNP). The typical resistance was not...
Gap junctions between β-cells participate in the precise regulation of insulin secretion. Adherens and their associated proteins are required for formation, function structural maintenance gap junctions. Increases number enhanced glucose-stimulated secretion observed during pregnancy. In contrast, protein restriction produces functional alterations that result poor response to glucose. We investigated whether pregnancy affects expression mRNA involved adherens pancreatic islets. An...