A5055326229- Plant-Microbe Interactions and Immunity
- Ubiquitin and proteasome pathways
- Genomics and Phylogenetic Studies
- Plant Pathogenic Bacteria Studies
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Plant Gene Expression Analysis
- Legume Nitrogen Fixing Symbiosis
- Photosynthetic Processes and Mechanisms
- Plant tissue culture and regeneration
- Plant pathogens and resistance mechanisms
- Chemical Reactions and Isotopes
- Chemical Synthesis and Analysis
- Transgenic Plants and Applications
- Glycosylation and Glycoproteins Research
- Silicon Effects in Agriculture
- Synthesis and bioactivity of alkaloids
- Toxic Organic Pollutants Impact
- Monoclonal and Polyclonal Antibodies Research
- Bacterial biofilms and quorum sensing
- Antimicrobial Peptides and Activities
- Bone Metabolism and Diseases
- Carbohydrate Chemistry and Synthesis
- Cytokine Signaling Pathways and Interactions
- Studies on Chitinases and Chitosanases
Chinese Academy of Agricultural Sciences
2021-2025
Institute of Plant Protection
2021-2025
Drug Discovery Laboratory (Norway)
2025
Purdue University West Lafayette
2025
Feed Research Institute
2024
Ministry of Agriculture and Rural Affairs
2024
Center for Life Sciences
2024
Tsinghua University
2024
Hunan Agricultural University
2021-2022
State Key Laboratory For Conservation and Utilization of Subtropical Agro-Bioresources
2017-2019
Rice blast and bacterial blight are important diseases of rice (Oryza sativa) caused by the fungus Magnaporthe oryzae bacterium Xanthomonas pv. (Xoo), respectively. Breeding varieties for broad-spectrum resistance is considered most effective sustainable approach to controlling both diseases. Although dominant genes have been extensively used in breeding production, generating disease-resistant altering susceptibility (S) that facilitate pathogen compatibility remains unexplored. Here, using...
Many transcription factors (TFs) in animals bind to both DNA and mRNA, regulating mRNA turnover. However, whether plant TFs function at the transcriptional post-transcriptional levels remains unknown. The rice (Oryza sativa) bZIP TF AVRPIZ-T-INTERACTING PROTEIN 5 (APIP5) negatively regulates programmed cell death blast resistance is targeted by effector AvrPiz-t of fungus Magnaporthe oryzae. We demonstrate that nuclear localization signal APIP5 essential for APIP5-mediated suppression...
Ubiquitination is essential for many cellular processes in eukaryotes, including 26S proteasome-dependent protein degradation, cell cycle progression, transcriptional regulation, and signal transduction. Although numerous ubiquitinated proteins have been empirically identified, their cognate ubiquitin E3 ligases remain largely unknown.
Knocking out three susceptibility genes (Pi21, Bsr-d1, and Xa5) in a rice breeding line that contains the resistance Piz-t produced enhanced broad-spectrum against fungal pathogen Magnaporthe oryzae bacterial Xanthomonas pv. without obvious growth penalty.
The initiative strategy for the development of novel anti-microbial agents usually uses virulence factors bacteria as a target, without affecting their growth and survival. type III secretion system (T3SS), one essential in most Gram-negative pathogenic because its highly conserved construct, has been regarded an effective target that developed new drugs. Xanthomonas oryzae pv. (Xoo) causes leaf blight diseases is important pathogens on rice. To find potential anti-virulence against this...
Cirsium japonicum, a traditional herb, exhibits significant anti-inflammatory activity. However, the main components and potential mechanisms of C. japonicum remain unclear. The aim this study is to investigate mechanism through network pharmacology cellular experiments. effective targets for activity were identified using Chinese medicine systematic database, TCMSP analysis platform, GeneCards database. drug–component–target–disease diagram was constructed Cytoscape 3.8.0 software, while...
<title>Abstract</title> Aflatoxin B1 (AFB1) and zearalenone (ZEN) are the most prevalent mycotoxins in production, posing a serious threat to food feed industry resulting substantial economic burden. Therefore, finding safe efficient method for biodegradation of is utmost important addressing this issue. <italic>Bacillus subtilis</italic> ZJ-2019-1, capable degrading AFB1 ZEN, was isolated cultured our laboratory vitro. In study, we conducted detoxification tests on ZEN using <italic>B....
Abstract Glycans play a crucial role in structure organization, energy metabolism, and signal transduction living organisms. Compared with proteins nucleic acids, glycans exhibit remarkable molecular heterogeneity, extensive conformational flexibility, diverse linkages. These properties pose significant challenges for obtaining high-resolution of glycans. Here, we report cryo-EM the heavily glycosylated Chlamydomonas mastigoneme at 2.3-2.5 Å resolutions. In addition to enabling analysis...