A5081225705- Plant-Microbe Interactions and Immunity
- Genomics and Phylogenetic Studies
- Plant Pathogenic Bacteria Studies
- Genetic Mapping and Diversity in Plants and Animals
- Rice Cultivation and Yield Improvement
- Ubiquitin and proteasome pathways
- Plant Stress Responses and Tolerance
- GABA and Rice Research
- Plant Gene Expression Analysis
- Insect-Plant Interactions and Control
- CRISPR and Genetic Engineering
- Plant Molecular Biology Research
- Plant Reproductive Biology
- Photosynthetic Processes and Mechanisms
- Research in Cotton Cultivation
- Plant Disease Resistance and Genetics
- Computational Drug Discovery Methods
- Ruminant Nutrition and Digestive Physiology
- Metabolomics and Mass Spectrometry Studies
- Environmental Quality and Pollution
- Legume Nitrogen Fixing Symbiosis
- Plant Virus Research Studies
- Genetic and phenotypic traits in livestock
- Protein Degradation and Inhibitors
- Histone Deacetylase Inhibitors Research
Institute of Crop Sciences
2011-2025
Chinese Academy of Agricultural Sciences
2014-2025
China Agricultural University
2022-2025
Shanghai Jiao Tong University
2022-2024
Zhengzhou University
2024
Institute of Plant Protection
2018-2023
Sanya University
2022-2023
Harvard University Press
2022
Second Military Medical University
2022
East China Normal University
2022
Improving the salt tolerance of direct-seeding rice at seed germination stage is a major breeding goal in many Asian rice-growing countries, where seedlings must often establish soils with high content. Thus, it important to understand genetic mechanisms and screen for germplasm stage. Here, we investigated seven germination-related traits under control salt-stress conditions conducted genome-wide association study based on re-sequencing 478 diverse accessions.The analysis used mixed linear...
Rice (Oryza sativa L.) not only provides insurance covering global food security but also works as a model for plant research. Currently, with overwhelmingly accumulated sequencing data, various databases were constructed different target users, including the Genome Variation Map (Song et al., 2018), RiceVarMap (Zhao 2015), SNP-Seek database (Alexandrov RPAN (Sun 2017) and MBK V1 (Institute of Genetics Developmental Biology, C.A.S., 2018). However, none them is designed to meet increasing...
Background Rice is sensitive to salt stress, especially at the seedling stage, with rice varieties differing remarkably in tolerance (ST). To understand physiological mechanisms of ST, we investigated stress responses metabolite level. Methods Gas chromatography-mass spectrometry was used profile changes salt-tolerant line FL478 and variety IR64 under a salt-stress time series. Additionally, several traits related ST were investigated. Results We characterized 92 primary metabolites leaves...
Nucleotide-binding leucine-rich repeat (NLR) proteins play critical roles in plant immunity. However, how NLRs are regulated and activate defense signaling is not fully understood. The rice (Oryza sativa) NLR receptor Piz-t confers broad-spectrum resistance to the fungal pathogen Magnaporthe oryzae RING-type E3 ligase AVRPIZ-T INTERACTING PROTEIN 10 (APIP10) negatively regulates accumulation. In this study, we found that APIP10 interacts with two transcription factors, VASCULAR PLANT...
Rice (Oryza sativa) is the main food for half of world's population, and considered model molecular biology studies monocotyledon species. Although rice genome was completely sequenced about 15 years ago, function most genes still unknown. In this study, we developed a vector toolkit that contains 42 vectors transient expression in protoplasts stable analysis transgenic rice. These have been successfully used to study protein subcellular localization, protein-protein interaction, gene...
Abstract To facilitate developing rice varieties tolerant to salt stress, a panel of 208 mini-core accessions collected from 25 countries were evaluated for 13 traits associated with tolerance (ST) at the germination and seedling stages. The showed tremendous variation all measured ST eight showing high levels either and/or both Using 395,553 SNP markers covering ~372 Mb genome multi-locus mixed linear models, 20 QTN 11 identified by GWAS, including 6 affecting stage 14 stage. integration...
Rice blast and bacterial blight are important diseases of rice (Oryza sativa) caused by the fungus Magnaporthe oryzae bacterium Xanthomonas pv. (Xoo), respectively. Breeding varieties for broad-spectrum resistance is considered most effective sustainable approach to controlling both diseases. Although dominant genes have been extensively used in breeding production, generating disease-resistant altering susceptibility (S) that facilitate pathogen compatibility remains unexplored. Here, using...
Many transcription factors (TFs) in animals bind to both DNA and mRNA, regulating mRNA turnover. However, whether plant TFs function at the transcriptional post-transcriptional levels remains unknown. The rice (Oryza sativa) bZIP TF AVRPIZ-T-INTERACTING PROTEIN 5 (APIP5) negatively regulates programmed cell death blast resistance is targeted by effector AvrPiz-t of fungus Magnaporthe oryzae. We demonstrate that nuclear localization signal APIP5 essential for APIP5-mediated suppression...
Ubiquitination is essential for many cellular processes in eukaryotes, including 26S proteasome-dependent protein degradation, cell cycle progression, transcriptional regulation, and signal transduction. Although numerous ubiquitinated proteins have been empirically identified, their cognate ubiquitin E3 ligases remain largely unknown.
Catalase negatively regulates plant immunity and is targeted degraded by ubiquitin E3 ligase.
Binding with proteins is a critical molecular initiating event through which environmental pollutants exert toxic effects in humans. Previous studies have been limited by the availability of three-dimensional (3D) protein structures and focused on only small set contaminants. Using highly accurate 3D structure predicted AlphaFold2, this study explored over 60 million interactions obtained docking between 20,503 human 1251 potential endocrine-disrupting chemicals. A total 66,613,773 results...
Amidst tightening regulations, the proliferation of next-generation per- and polyfluoroalkyl substances (PFAS) necessitates a deeper understanding their environmental fate potential risks. Here, we conducted comprehensive assessment PFAS in water sediment Taihu Lake, incorporating both nontarget target screening, seasonal geographical variation analysis, risk prioritization. A total 58 from 13 classes were identified, revealing complex contamination. In addition to short-chain perfluoroalkyl...
Gossypol removal is crucial for the resourceful utilization of cottonseed meals in food and feed industries. Herein, we investigated comprehensive detoxification mechanism a gossypol-tolerant strain
Genome-wide selection (GS) represents a contemporary methodology that harnesses comprehensive array of molecular markers across the entire genome. However, challenges such as lack informative and appropriate efficient GS model(s) have confined most GS-based breeding efforts to realm laboratory simulations (Wang et al., 2023). Compared conventional prediction models, machine learning (ML) algorithm provides new insights for solving big data analysis high-performance parallel computing. using...
Sheath blight (ShB), caused by Rhizoctonia solani Kühn, is one of the most destructive rice diseases. Developing ShB-resistant cultivars represents economical and environmentally sound strategy for managing ShB.To characterize genetic basis ShB resistance in rice, we conducted association studies traits related to resistance, namely culm length (CL), lesion height (LH), relative (RLH). Combined a single locus genome-wide scan multi-locus method using 2,977,750 single-nucleotide polymorphisms...
Blueberry (Vaccinium spp.) is a small berry with high economic value. Although cold storage can extend the time of blueberry to more than 60 days, it leads chilling injury (CI) displaying as pedicle pits; and samples 0 °C-30 days was critical point CI. However, little known about mechanism molecular basis response stress in have not been explained definitely. To comprehensively reveal CI mechanisms stress, we performed high-throughput RNA Seq analysis investigate gene regulation network 0d...
A one-/two-dimensional genome-wide association study (GWAS) strategy was adopted to investigate the genetic systems underlying reciprocal adaptation of rice (Oryza sativa) and its bacterial pathogen, Xanthomonas oryzae pv. (Xoo) using whole-genome sequencing large-scale phenotyping data 701 accessions 23 diverse Xoo strains. Forty-seven virulence-related genes 318 quantitative resistance (QR-genes) mainly located in 41 genomic regions, interactions between detected QR-genes were identified,...
Salinity–alkalinity stress is one of the main abiotic factors limiting rice production worldwide. With widespread use direct seeding technology, it has become increasingly important to improve tolerance salinity–alkalinity varieties at germination stage. Although we have a more comprehensive understanding salt in rice, genetic basis alkali still poorly understood. In this study, measured seven germination-related traits under and control conditions using 428 diverse accessions. The levels...
The receptor protein PEX5, an important component of peroxisomes, regulates growth, development, and immunity in yeast mammals. PEX5 also influences growth development plants, but whether it participates plant has remained unclear. Here, we report that knockdown OsPEX5 enhances resistance to the rice blast fungus Magnaporthe oryzae. We demonstrate interacts with E3 ubiquitin ligase APIP6, a positive regulator immunity. APIP6 ubiquitinates vitro promotes its degradation vivo via 26S...