A5101468858- Animal Nutrition and Physiology
- Gut microbiota and health
- Mycotoxins in Agriculture and Food
- Probiotics and Fermented Foods
- RNA Interference and Gene Delivery
- Meat and Animal Product Quality
- Distributed and Parallel Computing Systems
- Rabbits: Nutrition, Reproduction, Health
- Listeria monocytogenes in Food Safety
- Aquaculture Nutrition and Growth
- Livestock and Poultry Management
- Multi-Agent Systems and Negotiation
- Natural product bioactivities and synthesis
- Coccidia and coccidiosis research
- Viral gastroenteritis research and epidemiology
- Traditional Chinese Medicine Analysis
- Salmonella and Campylobacter epidemiology
- Pharmaceutical and Antibiotic Environmental Impacts
- Herpesvirus Infections and Treatments
- Clostridium difficile and Clostridium perfringens research
- Distributed systems and fault tolerance
- Cervical Cancer and HPV Research
- Bird parasitology and diseases
- Epigenetics and DNA Methylation
- Veterinary Oncology Research
Ministry of Agriculture and Rural Affairs
2019-2025
Feed Research Institute
2011-2025
Chinese Academy of Agricultural Sciences
2011-2025
Xinjiang Agricultural University
2008-2025
Heilongjiang University of Chinese Medicine
2024
University of Georgia
2017-2024
Beihang University
2022-2024
Hunan University of Traditional Chinese Medicine
2023
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2022
Wenzhou Medical University
2022
With the rapid advancement of genetic and protein engineering, proteins peptides have emerged as promising drug molecules for therapeutic applications. Consequently, there has been a growing interest in field chemical modification technology to address challenges associated with their clinical use, including clearance from circulation, immunogenicity, physical instabilities (such aggregation, adsorption, deamination, clipping, oxidation, etc.), enzymatic degradation. Polyethylene glycol...
The co-occurrence of aflatoxin B1 (AFB1) and zearalenone (ZEN) in grain-based food animal feed poses significant health risks to humans animals due their potent mutagenic, cytotoxic, carcinogenic properties. Conventional physical chemical methods are insufficient for effectively detoxifying multiple mycotoxins present feed. In this study, we evaluated the capability Bacillus subtilis ZJ-2019-1 (B. ZJ-2019-1) simultaneously degrade AFB1 ZEN while optimizing reaction enhance degradation...
Swine enteric coronaviruses are a group of most significant pathogens causing diarrhea in piglets with similar clinical symptoms and pathological changes. To develop simple, rapid, accurate, high-throughput detection method for diagnosis differential on swine coronaviruses, specific primers probes were designed based the highly conserved regions transmissible gastroenteritis virus (TGEV) N, porcine epidemic (PEDV) M, deltacoronavirus (PDCoV) alphacoronavirus (PEAV) N genes respectively. A...
The objective of this study was to evaluate the effect low-protein diets with amino acid supplementation on growth performance, carcass yield, meat quality and nitrogen excretion broilers raised under hot climate conditions during finisher period. In trial 1, from 28 49 days age were fed 18% crude protein (CP) as a positive control or 15% CP supplemented (1) DL-methionine (Met) + L-lysine (Lys), (2) Met Lys L-Arginine (Arg), (3) L-Valine (Val). 2, 30 45 age, an diet Met, Lys, Arg, Val,...
Lactobacilli have played an important role in the gut health of pets. The aim this research was to study effects isolated (named L11) on immune, nutrient metabolism, and cats. Twelve healthy adult cats were randomly assigned into two groups, control group (CONTROL, n = 6, without any probiotics product) treatment (probiotics, L11 109 CFU/kg feed), while using same dry diet. On day 28, blood fecal samples collected, biochemical indices, microbiota, short-chain fatty acids (SCFAs),...
Deoxynivalenol (DON) is commonly detected in cereals, and a threat to human animal health. The effects of microbiological detoxification are now being widely studied. A total 24 pigs (over four months) were randomly divided into three treatments. Treatment was fed with basal diet as the control group. B naturally DON-contaminated wheat negative C contaminated that also had Clostridium sp. WJ06, which used detoxicant. Growth performance, relative organ weight, intestinal morphology, flora...
The synthesis and the evaluation of efficacy a cycloruthenated complex, RuZ, is reported, to overcome multi-drug resistance (MDR) in cancer cells. RuZ can self-assemble into nanoaggregates cell culture medium, resulting high intracellular concentration MDR self-assembly significantly decreases oxygen consumption inhibits glycolysis, which cellular adenosine triphosphate (ATP) levels. decrease ATP levels its low affinity for ABCB1 ABCG2 transporters (which mediate MDR) increase retention by...
Abstract As an oxidant, deodorant and bleaching agent, the hypochlorous acid (HClO) hypochlorite (ClO − ) are widely used in corrosion inhibitors, textile dyes, pharmaceutical intermediates our daily lives. However, excess usage or aberrant accumulation of ClO leads to tissue damage some diseases even cancer. Therefore, it is necessary develop a fluorescent probe that specifically identifies . In this article, we synthesized deep‐red xanthene‐based (XA‐CN). The strong electron deficient...
Myostatin (MSTN) is suggested to mediate the effect of maternal nutrition on offspring phenotype, yet mechanisms underlying such adaptive gene regulation elusive. In this study, we determined effects dietary protein transcriptional MSTN in skeletal muscle pig offspring. Fourteen Meishan sows were fed either low-protein (LP) or standard-protein (SP) diets throughout gestation and lactation. expression longissimus dorsi was both at weaning finishing stages. mRNA abundance downregulated...
In this work of quercetin’s anti-proliferation action on A. flavus, we revealed that quercetin can effectively hamper the proliferation flavus in dose-effect and time-effect relationships. We tested whether induced apoptosis via various detection methods, such as phosphatidylserine externalization Hoechst 33342 staining. The results showed had no effect cell nucleus flavus. Simultaneously, reduced levels reactive oxygen species (ROS). For a better understanding molecular mechanism response...
Osteoarthritis (OA) is an age-related degenerative disease. Oxidative stress (OS) modulates OA pathogenesis by enhancing chondrocyte apoptosis and extracellular matrix (ECM) degeneration via activation of the endoplasmic reticulum (ER) stress. Prior studies revealed that safranal plays a critical role in multiple diseases treatments, but there are no reports on its effect OA. Therefore, investigating needed. As compound can lead excessive reactive oxygen species (ROS) accumulation,...
Gut microbiota plays important roles in mediating fat metabolic events humans and animals. However, the differences of meat quality traits related to lipid metabolism (MQT-LM) association with gut involving have not been well explored between Angus cattle (AG) Xinjiang brown (BC). Ten heads 18-month-old uncastrated male AG BC (5 each group) raised under identical conditions were selected test MQT-LM, i.e., backfat thickness (BFT), intramuscular (IMF) content, adipocyte areas (IAA), eye...
Aflatoxin B1 (AFB1), a ubiquitous mycotoxin in corn-based animal feed, particularly tropical regions, impairs liver function, induces oxidative stress and disrupts cellular pathways, potentially worsening bone health modern broilers. A 19-day experiment was conducted to investigate the effects of feeding increasing levels AFB1-contaminated feed (<2, 75–80, 150, 230–260 520–560 ppb) on mineralization markers broilers (n = 360). While growth performance remained unaffected up Day 19,...
This study was conducted to investigate the effects of different dosages tannic acid (TA) on growth performance, nutrient digestibility, gut health, immune system, oxidative status, microbial composition, volatile fatty acids (VFA), bone mineral density, and fat digestion accumulation in broilers find optimal TA for efficient health broilers. A total 320 male Cobb500 were randomly distributed 4 treatments with 8 replicates including 1) 0 (TA0): basal diet without TA; 2) 0.5 (TA0.5): g/kg 3)...
An experiment was conducted to evaluate effects of phytase and coccidial vaccine on growth performance, bone ash, 3-D microstructure, nutrient digestibility, gene expression intestinal biomarkers in broilers fed a regular or nutrient-reduced diet. The 2 × 4 factorial arrangement with 6 replicates per treatment 10 birds replicate. Two main factors were dietary treatments. treatments included: 1) positive control (PC; normal levels); 2) negative (NC; reduction 0.15% Ca avP 5% essential amino...