Zhenlong Wang

ORCID: 0000-0001-5946-2806
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About
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Research Areas
  • High Altitude and Hypoxia
  • Advanced Machining and Optimization Techniques
  • Physiological and biochemical adaptations
  • Primate Behavior and Ecology
  • Animal Behavior and Reproduction
  • Advanced machining processes and optimization
  • Hydrology and Watershed Management Studies
  • Cancer, Hypoxia, and Metabolism
  • Mitochondrial Function and Pathology
  • Metabolomics and Mass Spectrometry Studies
  • Animal Vocal Communication and Behavior
  • Antimicrobial Peptides and Activities
  • Advanced Surface Polishing Techniques
  • Genomics and Phylogenetic Studies
  • Environmental and Agricultural Sciences
  • Animal Ecology and Behavior Studies
  • Bat Biology and Ecology Studies
  • Neuroendocrine regulation and behavior
  • Epigenetics and DNA Methylation
  • Crop Yield and Soil Fertility
  • Neural dynamics and brain function
  • Cancer-related molecular mechanisms research
  • Soil and Unsaturated Flow
  • Animal Nutrition and Physiology
  • Plant responses to water stress

Zhengzhou University
2016-2025

Harbin Institute of Technology
2006-2025

Second Affiliated Hospital of Xi'an Jiaotong University
2010-2025

Anhui and Huaihe River Institute of Hydraulic Research
2011-2025

Feed Research Institute
2018-2025

Chinese Academy of Agricultural Sciences
2018-2025

Ministry of Agriculture and Rural Affairs
2020-2025

Shandong University
2025

Suzhou Research Institute
2025

Southwest Medical University
2023-2024

With the rapid advancement of genetic and protein engineering, proteins peptides have emerged as promising drug molecules for therapeutic applications. Consequently, there has been a growing interest in field chemical modification technology to address challenges associated with their clinical use, including clearance from circulation, immunogenicity, physical instabilities (such aggregation, adsorption, deamination, clipping, oxidation, etc.), enzymatic degradation. Polyethylene glycol...

10.3389/fphar.2024.1353626 article EN cc-by Frontiers in Pharmacology 2024-03-08

Oxygen is a critical factor for the survival of most lifeforms, as inadequate availability disrupts internal metabolic balance. Hypoxia-induced disruptions in glucose metabolism can be fatal to many animals. However, there currently limited research on energy species that inhabit environments with intermittently low oxygen levels. In this study, we investigated gluconeogenic response patterns adult Lasiopodomys brandtii (Brandt's vole) and Mus musculus (Kunming mice) under hypoxia (10% O2,...

10.1111/1749-4877.12961 article EN Integrative Zoology 2025-02-28

Abstract Pathogenic Escherichia coli can cause fatal diarrheal diseases in both animals and humans. However, no antibiotics or antimicrobial peptides (AMPs) adequately kill resistant bacteria clear bacterial endotoxin, lipopolysaccharide (LPS) which leads to inflammation sepsis. Here, the LPS-targeted smart chimeric (SCPs)-A6 G6 are generated by connecting LPS-targeting peptide-LBP14 killing domain-N6 via different linkers. Rigid flexible linkers retain independent biological activities from...

10.1038/s42003-020-0761-3 article EN cc-by Communications Biology 2020-01-23

Abstract Opium poppy ( Papaver somniferum ) is a source of morphine, codeine, and semisynthetic derivatives, including oxycodone naltrexone. Here, we report the de novo assembly genomic analysis P. traditional landrace ‘Chinese Herbal Medicine’. Variations between 2.62 Gb CHM genome that previously sequenced high noscapine 1 (HN1) variety were also explored. Among 79,668 protein-coding genes, functionally annotated 88.9%, compared to 68.8% reported in HN1 genome. Gene family 4DTv comparative...

10.1038/s41438-020-00435-5 article EN cc-by Horticulture Research 2021-01-01

Android has become the most prevalent mobile system, but in meanwhile malware on this platform is widespread. System call sequences are studied to detect malware. However, detection with these approaches relies common system-call-subsequences. It not so efficient because it difficult decide appropriate length of subsequences. To address issue, authors propose a new approach, back-propagation neural network Markov chains from system (BMSCS). treats one sequence as homogeneous stationary chain...

10.1049/iet-ifs.2015.0211 article EN IET Information Security 2016-03-16

A question of considerable importance is why some animals are able to succeed on a wide range diets whereas others more tightly constrained. Theory predicts that generalists should show flexible response for macronutrient regulation in the face ecologically driven constraint nutritional balance available foods, which modeling framework geometry has been quantitatively characterized as an "equal distance" regulatory model. This prediction, empirical support from several laboratory studies...

10.1093/beheco/ary003 article EN Behavioral Ecology 2018-04-24

The Huaihe River Basin is located in-between the north-south climate transitional zone in China and China's important congested area production base.The land-use of environment was occupied by for social economics.This paper aims to have a comprehensive understanding about vegetation evolution basin over past 30 years.In view 5 years (1985, 1990, 2000, 2005, 2014) data remote sensing NDVI, dynamic degree, transfer matrix were used analyze dynamics land use.Spatial overlay study change...

10.15244/pjoes/82900 article EN Polish Journal of Environmental Studies 2018-08-31

Pathogenesis of Crohn's disease (CD) is thought to involve the chronic activation T helper 1 (Th1)- and Th17-mediated inflammation, such as production interferon-gamma (IFN-γ) interleukin 17 (IL-17). However, studies have also shown that although IFN-γ required, IFN-γ-producing or T-bet-expressing Th1 cells are dispensable. We therefore examined B another source potentially supported intestinal inflammation in CD patients. found frequencies were significantly upregulated abundantly present...

10.1089/dna.2016.3304 article EN DNA and Cell Biology 2016-06-27

Microbial decomposition plays a crucial role in the incorporation of straw and biochar (SSB) into soil. Lime concretion black soil (LCBS) is typical low-medium crop yield soil, it also one main types for grain production China. However, link between SSB additions bacterial communities LCBS remains unclear. This study explored effects on community composition, structure co-occurrence network patterns at different depths maize growth stages. The results showed that PH, organic matter total...

10.3389/fmicb.2022.999399 article EN cc-by Frontiers in Microbiology 2022-09-30

Drought stress is one of the major abiotic stresses to wheat worldwide, with negative effects on growth and yield. Assessing genetic variation drought tolerance key agronomic physiological traits spring screening germplasm resources for higher yield stability are a prerequisite developing new, better-adapted varieties. This study evaluated nine important in 152 cultivars under non-stress (NS) drought-stress (DS) conditions. Under DS conditions, grain per plot (GYP) weight spike (GWE) were...

10.3390/agronomy13122968 article EN cc-by Agronomy 2023-11-30

Abstract Understanding streamflow generation at the catchment scale requires quantifying how different components of system are linked, and they respond to meteorological forcing. Here we present a proof‐of‐concept study characterizing dynamic linkages between precipitation, groundwater recharge, using data‐driven nonlinear deconvolution demixing approach, Ensemble Rainfall‐Runoff Analysis (ERRA). Streamflow in our mesoscale, intensively farmed test is flashy, but occurs time lags that too...

10.1029/2024wr037821 article EN cc-by Water Resources Research 2025-01-01

Cf-UHTC is an ideal aerospace material because of its exceptional properties, but machinability facing great challenges. Electrical discharge machining (EDM) offers a potential solution, removal mechanism remains unclear, lacking reliable prediction tools to guide the actual production. This paper deeply explores EDM Cf-ZrB2-SiC through single-pulse experiments, high-speed camera observations, and thermal–fluid coupling simulations, revealing key processes like heat transfer, phase...

10.3390/ma18020371 article EN Materials 2025-01-15

Breast cancer has become the most prevalent form of among women on a global scale. The early and timely diagnosis breast is utmost importance for improving survival rate patients with this disease. occurrence typically accompanied by dysregulation multiple microRNA (miRNA) expression profiles. Consequently, simultaneous detection miRNAs vital accurate cancer. In study, bipolar self-powered sensor was developed miRNA-451 miRNA-145 biomarkers based specific catalytic properties enzymes....

10.1021/acsnano.4c16423 article EN ACS Nano 2025-02-26
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