A5044005664- COVID-19 epidemiological studies
- SARS-CoV-2 and COVID-19 Research
- Influenza Virus Research Studies
- COVID-19 Pandemic Impacts
- SARS-CoV-2 detection and testing
- Viral Infections and Outbreaks Research
- Respiratory viral infections research
- Animal Disease Management and Epidemiology
- COVID-19 and Mental Health
- Data-Driven Disease Surveillance
- Climate Change and Health Impacts
- Vaccine Coverage and Hesitancy
- Viral Infections and Immunology Research
- Mathematical and Theoretical Epidemiology and Ecology Models
- Air Quality and Health Impacts
- Health disparities and outcomes
- COVID-19 Clinical Research Studies
- Infection Control and Ventilation
- Virology and Viral Diseases
- COVID-19 and healthcare impacts
- Zoonotic diseases and public health
- Evolution and Genetic Dynamics
- Forecasting Techniques and Applications
- COVID-19 Impact on Reproduction
- Wireless Networks and Protocols
University of Hong Kong
2018-2025
Laboratory of Data Discovery for Health
2021-2024
Hong Kong Science and Technology Parks Corporation
2021-2024
Hong Kong Polytechnic University
2022
Chinese University of Hong Kong
2022
Tel Aviv University
2022
Columbus State University
2022
Shanghai Normal University
2022
Shanxi University
2022
RMIT University
2022
A range of public health measures have been implemented to suppress local transmission coronavirus disease 2019 (COVID-19) in Hong Kong. We examined the effect these interventions and behavioural changes on incidence COVID-19, as well influenza virus infections, which might share some aspects dynamics with COVID-19.We analysed data laboratory-confirmed COVID-19 cases, surveillance outpatients all ages, hospitalisations children. estimated daily effective reproduction number (Rt) for H1N1...
From cough to splutter In epidemiology, serial intervals are measured from when one infected person starts show symptoms the next becomes symptomatic. For any specific infection, interval is assumed be a fixed characteristic. Using valuable transmission pair data for coronavirus disease (COVID-19) in mainland China, Ali et al. noticed that average changed as nonpharmaceutical interventions were introduced. mid-January 2020, on 7.8 days, whereas early February they decreased an of 2.2 days....
Our analysis of data collected from multiple epidemics in Hong Kong indicated a shorter serial interval and generation time infections with the SARS-CoV-2 Omicron variant. The age-specific case-fatality risk for BA.2.2 case-patients without complete primary vaccination was comparable to that persons infected ancestral strains earlier waves.
BackgroundThe Delta variant of SARS-CoV-2 had become predominant globally by November 2021.AimWe evaluated transmission dynamics and epidemiological characteristics the in an outbreak southern China.MethodsData on confirmed COVID-19 cases their close contacts were retrospectively collected from that occurred Guangdong, China May June 2021. Key parameters, temporal trend viral loads secondary attack rates estimated. We also association vaccination with load transmission.ResultsWe identified...
The omicron variant (B.1.1.529) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was the predominant in South Korea from late January 2022. In this study, we aimed to report early estimates serial interval distribution and reproduction number quantify transmissibility between 25 November 2021 31 December 2021. We analyzed 427 local cases reconstructed 73 transmission pairs. used a maximum likelihood estimation assess pair data numbers 74 first outbreak. estimated that mean...
Knowledge on the epidemiological features and transmission patterns of novel coronavirus disease (COVID-19) is accumulating. Detailed line-list data with household settings can advance understanding COVID-19 dynamics.A unique database detailed demographic characteristics, travel history, social relationships, timelines for 1407 pairs that formed 643 clusters in mainland China was reconstructed from 9120 confirmed cases reported during 15 January-29 February 2020. Statistical model fittings...
ABSTRACT Background A range of public health measures have been implemented to delay and reduce local transmission COVID-19 in Hong Kong, there major changes behaviours the general public. We examined effect these interventions behavioral on incidence as well influenza virus infections which may share some aspects dynamics with COVID-19. Methods reviewed policy measured population through two telephone surveys, January 20-23 February 11-14. analysed data laboratory-confirmed cases,...
ABSTRACT Background The Delta variant of SARS-CoV-2 has become predominant globally. We evaluated the transmission dynamics and epidemiological characteristics in an outbreak southern China. Methods Data on confirmed cases their close contacts were retrospectively collected from that occurred Guangdong, China May-June 2021. Key parameters, temporal trend viral loads secondary attack rates estimated compared between wild-type virus. also association vaccination with load transmission. Results...
Abstract We used national sentinel surveillance data in China for 2005–2016 to examine the lineage-specific epidemiology of influenza B. Influenza B viruses circulated every year with relatively lower activity than A. B/Yamagata was more frequently detected adults children.
In winter 2018, schools in Hong Kong were closed 1 week before the scheduled Chinese New Year holiday to mitigate an influenza B virus epidemic. The intervention occurred after epidemic peak and reduced overall incidence by ≈4.2%. School-based vaccination programs should be implemented more effectively reduce illnesses.
We analyzed transmission of coronavirus disease outside the Daegu-Gyeongsangbuk provincial region in South Korea. estimated that nonpharmaceutical measures reduced transmissibility by a maximum 34% without resorting to strict lockdown strategy. To optimize epidemic control, continuous efforts monitor are needed.
Influenza epidemics occur during winter in temperate zones, but have less regular seasonality the subtropics and tropics. Here we quantified role of environmental drivers influenza subtropical China.We used weekly surveillance data on virus activity mainland China Hong Kong from 2005 through 2016. We estimated transmissibility via instantaneous reproduction number (Rt), a real-time measure transmissibility, examined its relationship with different climactic allowed for timing school holidays...
Abstract Background After relaxing social distancing measures, South Korea experienced a resurgent second epidemic wave of coronavirus disease 2019 (COVID-19). In this study, we aimed to identify the transmission dynamics severe acute respiratory syndrome 2 (SARS-CoV-2) infections and assess impact COVID-19 case finding contact tracing in each wave. Methods We collected data on cases published by local public health authorities divided study into two periods (19 January–19 April 2020 for...
Hong Kong has implemented stringent public health and social measures (PHSMs) to curb each of the four COVID-19 epidemic waves since January 2020. The third wave between July September 2020 was brought under control within 2 m, while fourth starting from end October taken longer bring lasted at least 5 mo. Here, we report pandemic fatigue as one potential reasons for reduced impact PHSMs on transmission in wave. We contacted either 500 or 1,000 local residents through weekly random-digit...
ABSTRACT Hong Kong reported 12,631 confirmed COVID-19 cases and 213 deaths in the first two years of pandemic but experienced a major wave predominantly Omicron BA.2.2 early 2022 with over 1.1 million SARS-CoV-2 infections more than 7900 deaths. Our data indicated shorter incubation period, serial interval, generation time other variants. without complete primary vaccination series appeared to face similar fatality risk those infected earlier waves ancestral strain.
Abstract Many locations around the world have used real-time estimates of time-varying effective reproductive number ( $${R}_{t}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msub> <mml:mrow> <mml:mi>R</mml:mi> </mml:mrow> <mml:mi>t</mml:mi> </mml:msub> </mml:math> ) COVID-19 to provide evidence transmission intensity inform control strategies. Estimates are typically based on statistical models applied case counts and suffer lags more than a week because latent period...
We estimated mean serial interval and superspreading potential for the Delta variant of severe acute respiratory syndrome coronavirus 2 in South Korea. Intervals were similar first (3.7 days) second (3.5 study periods. Risk events was also similar; 23% 25% cases, respectively, seeded 80% transmissions.
To model estimated deaths averted by COVID-19 vaccines, we used state-of-the-art mathematical modeling, likelihood-based inference, and reported death vaccination data. We that >1.5 million were in 12 countries. Our can help assess effectiveness of the program, which is crucial for curbing pandemic.
The generation time distribution, reflecting the between successive infections in transmission chains, is a key epidemiological parameter for describing COVID-19 dynamics. However, because exact infection times are rarely known, it often approximated by serial interval distribution. This approximation holds under assumption that infectors and infectees share same incubation period which may not always be true. We estimated distributions using 629 pairs reconstructed investigating 2989...
School closures are considered as a potential nonpharmaceutical intervention to mitigate severe influenza epidemics and pandemics. In this study, we assessed the effects of scheduled school closure on transmission using surveillance data before, during, after spring breaks in South Korea, 2014-2016. During breaks, was reduced by 27%-39%, while overall reduction transmissibility estimated be 6%-23%, with greater observed among school-aged children.