Wei Liu

ORCID: 0000-0002-8649-8625
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Research Areas
  • Phytochemicals and Antioxidant Activities
  • Phytochemistry and Biological Activities
  • Plant tissue culture and regeneration
  • Natural product bioactivities and synthesis
  • Pharmacological Effects of Natural Compounds
  • Plant biochemistry and biosynthesis
  • Food Quality and Safety Studies
  • Traditional Chinese Medicine Analysis
  • Berberine and alkaloids research
  • Ginseng Biological Effects and Applications
  • Microbial Metabolites in Food Biotechnology
  • Protein Hydrolysis and Bioactive Peptides
  • Metabolomics and Mass Spectrometry Studies
  • Nuts composition and effects
  • Biochemical effects in animals
  • Traditional Chinese Medicine Studies
  • Microbial Metabolic Engineering and Bioproduction
  • Agriculture, Soil, Plant Science
  • Plant Pathogens and Fungal Diseases
  • Plant Gene Expression Analysis
  • Food composition and properties
  • Proteins in Food Systems
  • Microbial Metabolism and Applications
  • Tea Polyphenols and Effects
  • Plant Genetic and Mutation Studies

Ministry of Agriculture and Rural Affairs
2024-2025

Guangdong Academy of Agricultural Sciences
2021-2025

Air Force General Hospital PLA
2020-2024

Jiangnan University
2018-2024

Chinese Academy of Medical Sciences & Peking Union Medical College
2024

China Pharmaceutical University
2024

State Key Laboratory of Natural Medicine
2024

Hunan Agricultural University
2017-2024

Beijing University of Chinese Medicine
2024

Henan University of Science and Technology
2016-2024

Abstract Environmental factors may influence types and contents of active substances. This study investigated the environmental on substance antioxidant activity Potentilla fruticosa L. from different regions China. Also, HPLC fingerprint similarity analysis (SA) coupled with hierarchical cluster (HCA) discriminant (DA) were further introduced for accurate classification quality assessment P. . The results showed that altitude was significantly negatively correlated to content tannin ( P...

10.1038/srep28591 article EN cc-by Scientific Reports 2016-07-04

Recent advancements in modern science have provided robust tools for drug discovery. The rapid development of transcriptome sequencing technologies has given rise to single-cell transcriptomics and single-nucleus transcriptomics, increasing the accuracy accelerating discovery process. With evolution spatial (ST) technology emerged as a derivative approach. Spatial hot topic field omics research recent years; it not only provides information on gene expression levels but also offers...

10.7150/thno.95908 article EN cc-by Theranostics 2024-01-01

Geraniol is an acyclic monoterpene alcohol, which exhibits good prospect as a gasoline alternative. naturally encountered in plants at low concentrations and attractive target for microbial engineering. has been heterologously produced Escherichia coli, but the titer hinders its industrial applications. Moreover, bioconversion of geraniol by E. coli remains largely unknown. Recombinant overexpression Ocimum basilicum synthase, Abies grandis geranyl diphosphate heterotic mevalonate pathway...

10.1186/s13068-016-0466-5 article EN cc-by Biotechnology for Biofuels 2016-03-11

Litchi is one of the ancient fruits that originated in China, renowned for its high nutrition and rich flavor, Xianjinfeng (XJF) stands as most notable varieties terms flavor. Investigating metabolic changes taste compounds during fruit development offers deeper insights into formation patterns quality. In this study, we conducted extensive metabonomic research on accumulation (carbohydrates, organic acids, amino acids) across three developmental stages XJF litchi. A total 238 metabolites...

10.3390/foods14010144 article EN cc-by Foods 2025-01-06

We describe a highly sensitive method for the detection of 7-dehydrocholesterol (7-DHC), biosynthetic precursor cholesterol, based on its reactivity with 4-phenyl-1,2,4-triazoline-3,5-dione (PTAD) in Diels-Alder cycloaddition reaction. Samples biological tissues and fluids added deuterium-labeled internal standards were derivatized PTAD analyzed by LC-MS. This protocol permits fast processing samples, short chromatography times, high sensitivity. applied this to analysis cells, blood, from...

10.1194/jlr.d043877 article EN cc-by Journal of Lipid Research 2013-11-21

Abstract Sanguinarine is currently widely used to replace antibiotic growth promoters in animal feeding and has demonstrated useful anticancer activity. Currently, the main source of sanguinarine from an important medicinal plant, Macleaya cordata . To obtain a new production, we established hairy root cultures M by co-cultivating leaf stem explants with Agrobacterium rhizogenes Except co-cultivation medium, all media contained 200 mg/L timentin eliminate A Through comparing metabolic...

10.1038/s41598-018-30560-0 article EN cc-by Scientific Reports 2018-08-06

The aim of this study was to characterize the composition soybean germ and its oil from Northeast (NE-SG) Shandong Province (SD-SG) China with a focus on fatty acids phytosterols as well physicochemical properties. results show that average contents water, protein, crude fat, fiber ash NE-SG SD-SG were 8.23 ± 0.11%, 40.47 0.10%, 11.65 0.14%, 6.20 0.09% 4.79 respectively. major two oils linoleic acid (NE-SGO, 55.45%; SD-SGO, 52.15%), alpha-linolenic 16.21%; 18.50%), palmitic 12.59%; 11.40%)...

10.1039/c9ra08771k article EN cc-by-nc RSC Advances 2019-01-01

Litchi is an important fruit cultivated in tropical and subtropical areas with high nutritious delicious flavor the pulp main part of consumed. Previous studies found that litchi had total phenol content antioxidant activity, but most them focused on identification single or a few phenolic components low throughput test, metabolic differences cultivars are still unknown to some extent. In this study we used widely targeted metabolome based ultra-performance liquid chromatography coupled mass...

10.3390/molecules26041181 article EN cc-by Molecules 2021-02-23

Panax ginseng cultivated under the forest is popular because its shape and effective ingredients are similar to wild ginseng. The growth of P. in larch generally better than broad-leaved forest, incidence rate diseases low. Therefore, selection species one basic factors successful cropping

10.1186/s12863-023-01154-1 article EN cc-by BMC Genomic Data 2023-09-14

The Manchurian walnut (Juglans mandshurica Maxim.) is rich in proteins, whereas this resource has not been used efficiently.The antifatigue, antioxidative and immunoregulatory effects of hydrolysate peptides (MWHPs) were evaluated study.MWHPs with a degree hydrolysis 32.23% ultrafiltered divided into three fractions, namely, high (> 10 kDa), medium (3-10 low molecular weight (< 3 then fed to mice continuously at doses 200, 400 or 800 mg/(kg•d).The antioxidative, the tested on second fourth...

10.3724/sp.j.1447.gost.2018.18028 article EN cc-by-nc-nd Grain & Oil Science and Technology 2018-01-01

Hazelnut dregs are by-products of hazelnut oil expression, which have not been fully exploited. This research aims to assess the immunomodulatory function hydrolysed peptides (HHPs).HHPs with a hydrolysis degree 38.08% were divided into three fractions by ultra-filtration: high molecular weight peptide (>10 kDa), medium (3 kDa 10 and low (<3 kDa). Mice fed daily HHPs different weights at doses 200, 400, 800 mg kg(-1) body weight. On 10th, 20th 30th day feeding, representative immune indexes...

10.1002/jsfa.7535 article EN Journal of the Science of Food and Agriculture 2015-11-20

Abstract The chemical components and antioxidant activity of 16 Rehmannia glutinosa samples were investigated to reveal the high‐quality raw resource for pharmaceutical products. 22 main detected with significant content differences ( P &lt;0.05). contents 14 substances reached maximum in S1 sample such as catalpol (6.74 mg g −1 ), rehmaionoside A (1.93 ) rehmannioside D (5.13 ). However, distribution other eight had no obvious change regulation. Three evaluation methods commonly showed that...

10.1002/cbdv.202000341 article EN Chemistry & Biodiversity 2020-05-27

Cisplatin-evoked profound gastrointestinal symptomatology is one of the most common side effects chemotherapy drugs, further causing cell damage, diarrhea and vomiting.

10.1039/d2fo00776b article EN Food & Function 2022-01-01

Extracts of Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum, inhibited quorum sensing in Chromobacterium violaceum CV026. G. lucidum fruiting bodies were milled and extracted with ethyl acetate. The crude extract was dissolved an appropriate concentration methanol, sterilized by filtration through a 0.22-μm membrane filter, added to Ch. Violaceum CV026 cultures, which used as indicator monitor inhibition. Inhibitory activity measured quantifying violacein production using microplate...

10.1615/intjmedmushr.v13.i6.80 article EN International journal of medicinal mushrooms 2011-01-01
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