A5101615805- Microfluidic and Bio-sensing Technologies
- Microstructure and Mechanical Properties of Steels
- Metallurgy and Material Forming
- Magnetic Properties and Applications
- Glaucoma and retinal disorders
- Nanopore and Nanochannel Transport Studies
- Microfluidic and Capillary Electrophoresis Applications
- Single-cell and spatial transcriptomics
- Retinal Diseases and Treatments
- Gut microbiota and health
- Corneal surgery and disorders
- Advanced biosensing and bioanalysis techniques
- Microstructure and mechanical properties
- Tryptophan and brain disorders
- Electronic and Structural Properties of Oxides
- Biosensors and Analytical Detection
- Acute Myeloid Leukemia Research
- Bacterial Identification and Susceptibility Testing
- Liver Disease Diagnosis and Treatment
- Natural Products and Biological Research
- Metal Forming Simulation Techniques
- Polysaccharides and Plant Cell Walls
- Polysaccharides Composition and Applications
- Cardiac Fibrosis and Remodeling
- Meat and Animal Product Quality
Shandong First Medical University
2020-2024
University of Science and Technology Beijing
2023-2024
Tianjin University of Traditional Chinese Medicine
2023-2024
Tianjin University
2024
State Key Laboratory of Natural Medicine
2018-2024
China Pharmaceutical University
2016-2024
Weatherford College
2024
Arizona State University
2019-2024
Shandong Eye Hospital
2020-2024
First Affiliated Hospital of Bengbu Medical College
2024
Neural stem and progenitor cells (NSPCs) are an extremely important group of that form the central nervous system during development have potential to repair damage in conditions such as stroke impairment, spinal cord injury Parkinson's disease degradation. Current schemes for separation NSPCs inadequate due complexity diversity population lack sufficient markers distinguish diverse cell types. This study presents unbiased high-resolution characterization NSPC subpopulations using direct...
Proteins are perhaps the most important yet frustratingly complicated and difficult class of compounds to analyze, manipulate, use. One very attractive option characterize differentially concentrate proteins is dielectrophoresis, but according accepted theory, force on smaller particles size too low overcome diffusive action. Here, three model proteins, immunoglobulin G, α-chymotrypsinogen A, lysozyme, shown generate forces much larger than predicted by established theory more consistent...
To overcome the disadvantage of Arrhenius constitutive (AC) equation in predicting complex nonlinear flow behaviors, this work employed an artificial neural network (ANN) to introduce a proportional coefficient reflecting changes softening mechanisms under various hot deformation conditions, thereby enhancing applicability AC model. The result demonstrates that, compared model, ANN-AC model effectively compensates for errors resulting from different during deformation, with RMSE and MAPE...
Herein, SrSnO3 perovskite and Nd2Sn2O7 pyrochlore with definite structures have been synthesized using a hydrothermal method, the differences in their reactive sites for oxidative coupling of methane (OCM) are investigated. The primary products C2 hydrocarbons COx, respectively. selectivity is primarily affected by basic chemisorbed oxygen species O22-. For pyrochlore, key factors affecting conversion COx acidic (chemisorbed weakly bonded lattice oxygen). directly generated through intrinsic...
Abstract It has been reported that growth differentiation factor 11 (GDF11) protects against myocardial ischemia/reperfusion (IR) injury, but the underlying mechanisms have not fully clarified. Considering GDF11 plays a role in aging/rejuvenation process and aging is associated with telomere shortening cardiac dysfunction, we hypothesized might protect IR injury by activating telomerase. Human plasma levels were significantly lower acute coronary syndrome patients than chronic patients. mice...
Understanding the recrystallization behavior of cold‐rolled silicon steel during continuous heating is essential for optimizing annealing parameters and accurately controlling material performance. To address limitations isothermal studies in interpreting actual processes, this study investigates kinetics Fe–2.3 wt%Si using a three‐point bending method. The method effectively determines characteristic temperatures. Interestingly, these temperatures remain unaffected by initial load but shift...
Salmonella is an important pathogen and a world-wide threat to food safety public health. Surveillance of serotypes fundamental biological biochemical studies are supported by wide variety established emerging bioanalytical techniques. These include classic serotyping based on the Kauffmann-White nomenclature whole genome sequencing strategy. Another strategy native cell biophysical characterization which has yet be applied Salmonella. However, this technique been shown provide high...
A simple label-free and non-invasive analysis method is established to detect phagocytic activity screen medicine at single cell level.
The most common form of leukemia in adults is acute leukemia. Drug differentiation control an extremely critical treatment for Unfortunately, current techniques detecting experience long time and complex steps verification hindering the pace medicine discovery: flow cytometry RT-PCR are highly accurate efficient at a cost inconvenient fluorescent labeling or high risk contamination; conventional staining leads to cell death unavailable further pharmacological tests. There great interest...
To evaluate clinical efficacy and safety of single Ultrasound Cyclo-Plasty (UCP) in the treatment advanced refractory glaucoma.From January 2018 to August 2018, 25 patients (25 eyes) with glaucoma intraocular pressure (IOP) not controlled by drugs or conventional filtering surgery were included study. All subjects (neovascular [n = 12], secondary 6], angle closure primary open 1]) underwent 8-sector Cyclo-Plasty. Patients followed-up at Day 1, Week 3, 6, 12 months, during which IOP, number...
Organelle heterogeneity and inter-organelle contacts within a single cell contribute to the limited sensitivity of current organelle separation techniques, thus hindering subpopulation characterization. Here, we use direct insulator-based dielectrophoresis (DC-iDEP) as an unbiased method demonstrate its capability by identifying distinct distribution patterns insulin vesicles from INS-1E insulinoma cells. A multiple voltage DC-iDEP strategy with increased range has been applied,...
In the face of worsening water quality and escalating environmental emergencies, this study developed a paper-based microfluidic disk for rapid, on-site determination ammonia nitrogen, nitrates, nitrites, phosphates in water. The method utilizes centrifugal microfluidics technology, thus simplifying operation while eliminating need reagent preparation. Experimental results demonstrate that requires only 80 microliters sample 2 minutes to complete quantitative analysis four nutrients, with...
Right ventricular (RV) dysfunction induced type II cardiorenal syndrome (CRS) has a high mortality rate, but little attention been paid to this disease, and its unique molecular characteristics remain unclear. This study aims investigate the transcriptomic expression profile in disease identify key RNA pairs that regulate related signaling networks. We established an RV dysfunction-induced CRS mouse model by pulmonary artery constriction (PAC). PAC mice developed severe hypertrophy fibrosis;...
AIM: To investigate the association of axial length (AL), lens thickness (LT), and vault (LV) with postoperative anterior chamber angle metrics after laser peripheral iridotomy (LPI). METHODS: Prospective observational study 69 patients (97 eyes) were diagnosed as primary angle-closure suspect (PACS), closure (PAC) or glaucoma (PACG). AL, LT, central depth (ACD), opening distance (AOD), trabecular iris (TIA), recess area (ARA) measured before 1wk LPI. The between LV ACD, AOD, TIA, ARA...
Abstract Nanochannel‐based confinement effect is a fascinating signal transduction strategy for high‐performance sensing, but only size focused on while other effects are unexplored. Here, highly integrated nanochannel‐electrodes chip (INEC) created and size/volume‐dual‐confinement enzyme catalysis model rapid sensitive bacteria detection developed. The INEC, by directly sandwiching nanochannel (60 µm in thickness) nanoporous gold layers, creates micro‐droplet‐based electrochemical cell...