A5068421631- Anesthesia and Neurotoxicity Research
- Congenital Diaphragmatic Hernia Studies
- Tracheal and airway disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Sarcoma Diagnosis and Treatment
- Pediatric Pain Management Techniques
- Anesthesia and Sedative Agents
- Esophageal and GI Pathology
- Traumatic Brain Injury and Neurovascular Disturbances
- Anesthesia and Pain Management
- Neonatal Respiratory Health Research
- Congenital Anomalies and Fetal Surgery
- Colorectal and Anal Carcinomas
- Respiratory Support and Mechanisms
- Airway Management and Intubation Techniques
- Intensive Care Unit Cognitive Disorders
- Ion Transport and Channel Regulation
- Cardiac electrophysiology and arrhythmias
- Acute Kidney Injury Research
- Urologic and reproductive health conditions
- Pharmacogenetics and Drug Metabolism
- Global Health and Surgery
- Craniofacial Disorders and Treatments
- Neurofibromatosis and Schwannoma Cases
- Abdominal vascular conditions and treatments
Universitätsklinikum Tübingen
2022-2025
University of Tübingen
2009-2024
University Children's Hospital Tübingen
2016-2024
University Medical Center Hamburg-Eppendorf
2023
Orthopädische Universitätsklinik
2023
Universität Hamburg
2023
Leibniz University Hannover
2023
University of Lübeck
2022
ABSTRACT Background Pediatric abdominal rhabdomyosarcoma (RMS) represents an oncosurgical challenge. For adults with peritoneal carcinomatosis and for children/adolescents desmoplastic small round cell tumors (DSRCT), cytoreductive surgery (CRS) combined hyperthermic intraperitoneal chemotherapy (HIPEC) has been shown to be effective treatment. Thereby, we present the largest series on CRS HIPEC in patients RMS. Patients Methods Between August 2013 January 2024, 18 (9 female 9 male) RMS...
Abstract The management of congenital lung malformations (CLM) remains controversial. aim this study was to analyze the timing, approach, and outcomes surgical treatment in children with CLM. A cohort conducted comparing CLM who underwent thoracoscopic resection open via thoracotomy. All were treated according an institutionalized multidisciplinary coordinated algorithm. Between 2002 2019, 68 treated. Thoracoscopic (n=44) resulted a statistically significant longer operative time (mean 169...
Background/Objectives: In bilateral nephroblastoma and high-risk neuroblastoma in children with extensive tumor involvement of the renal vessels or pedicle, complete resection preservation healthy tissue is not feasible situ nephron-sparing surgery vascular replacement. The aim this study was to present our experience ante autotransplantation (RATX) these children. Methods: A retrospective who underwent RATX at an international referral center for pediatric surgical oncology between 2006...
Summary Background Intraoperative hypercapnia and acidosis are risk factors during thoracoscopy in neonates infants. Methods In a prospective pilot study, we evaluated the effects of infants on cerebral microcirculation, oxygen saturation, consumption. Regional saturation blood flow were measured noninvasively using new device combining laser Doppler flowmetry white light spectrometry. Additionally, fractional tissue extraction approximated consumption calculated. Fifteen undergoing studied...
Background We demonstrated recently that the implementation of a nurse-driven analgesia and sedation protocol (pediatric [pASP]) for mechanically ventilated nonpostsurgical patients reduces total dose benzodiazepines withdrawal symptoms significantly. It has not been investigated if these results can also be expected in group undergoing surgery. Objectives To evaluate effects pASP postsurgical children regarding drug dosage, duration mechanical ventilation, length stay, rate symptoms....
Solid tumors of the cervicothoracic junction, posterior mediastinum, or bilateral dorsal thoracic represent a challenge in pediatric surgical oncology. The aim this study was to evaluate trap-door thoracotomy and clamshell as approaches. A single-center retrospective children with solid these specific localizations performed. From 2015 2023, 26 (17 girls; 9 boys) were treated at median age 54 months (range 8–229). Tumor resection performed for neuroblastoma (n = 11); metastatic disease 7);...
Urla, Cristian MD; Seitz, Guido MD, PhD; Tsiflikas, Ilias Handgretinger, Rupert Fideler, Frank Neunhoeffer, Felix Warmann, Steven W. Fuchs, Jörg PhD Author Information
Inducing general anesthesia (GA) in children can considerably affect blood pressure, and the rate of severe critical events owing to this remains high. Cerebrovascular autoregulation (CAR) protects brain against blood-flow-related injury. Impaired CAR may contribute risk cerebral hypoxic-ischemic or hyperemic However, pressure limits (LAR) infants are unclear.In pilot study was monitored prospectively 20 patients aged <4 years receiving elective surgery under GA. Cardiac- neurosurgical...
In children with bladder/prostate (BP) and perianal rhabdomyosarcoma (RMS), we use a hybrid treatment concept for those suitable, combining organ-preserving tumor resection high-dose rate brachytherapy (HDR-BT). This has been shown to improve outcomes. However, it is associated specific challenges the clinicians. The exact position of tubes BT prerequisite precise radiotherapy. It can finally be determined only an MRI or CT scan. We evaluated intraoperative (iMRI) control radiotherapy...
Abstract Background Intraoperative blood pressure is a relevant variable for postoperative outcome in infants undergoing surgical procedures. It therefore important to know whether the type of anesthesia has an impact on intraoperative management very low birth weight infants. Here, we retrospectively analyzed birthweight receiving either awake caudal without sedation, or block combination with general anesthesia, both open inguinal hernia repair. Methods Ethical approval was provided by...
<title>Abstract</title> <italic>Background:</italic> Craniosynostosis surgery (CS) is associated with severe diffuse perioperative bleeding which can result in a significant coagulopathy. The Thrombelastograph Coagulation Analyzer TEG 6s modern point of care (POC) device for rapid detection coagulation disorders and the guidance factor substitution. By now little known about changes values infants toddlers coagulopathies. aim this study was to monitor, compare relate parameters conventional...
Under- or overdosage of medication can lead to severe side effects in children. To avoid this, precise knowledge age-specific liberation, absorption, distribution, metabolism and excretion - LADME for short is necessary. Absorption take place intravenously, orally, rectally, intranasally, transdermally epidurally/caudally associated with numerous special features children, depending on age route application. The distribution children faster due more permeable organ barriers between...
Since May 2021, an extension of §1631 has been implemented in Germany: gender reassignment surgery patients with differences sex development (DSD) before the capacity for self-determined consent needs interdisciplinary expert opinion and family court judge.The only exceptional cases are those which patient's health would be seriously endangered without such operation.Congenital adrenal hyperplasia (CAH) is classified to group DSD, representing one DSD-groups highest incidence.Contrary...
Kritische Ereignisse sind in der Kinderanästhesie nach wie vor häufiger als bei erwachsenen Patienten. Sicherheit und Outcome behandelten Kinder ist entscheidend davon abhängig, gut diese kritischen gemanagt werden. Dieser Beitrag beschreibt häufige perioperative Komplikationen zeigt Möglichkeiten zur Risikoabschätzung Optimierung auf, die dazu beitragen können, schwerwiegende langfristige Folgen zu reduzieren.
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