A5029520303- Colorectal Cancer Surgical Treatments
- Optical Imaging and Spectroscopy Techniques
- Surgical Simulation and Training
- Colorectal Cancer Screening and Detection
- Medical Image Segmentation Techniques
- Sarcoma Diagnosis and Treatment
- Neuroblastoma Research and Treatments
- Orthopedic Surgery and Rehabilitation
- Anatomy and Medical Technology
- Neuroendocrine Tumor Research Advances
- Photoacoustic and Ultrasonic Imaging
- Reconstructive Facial Surgery Techniques
- Non-Invasive Vital Sign Monitoring
- Bariatric Surgery and Outcomes
- AI in cancer detection
- Congenital Diaphragmatic Hernia Studies
- Dermatologic Treatments and Research
- Colorectal and Anal Carcinomas
- Infrared Thermography in Medicine
- Pain Management and Placebo Effect
- Medicine and Dermatology Studies History
- Health, Environment, Cognitive Aging
- Augmented Reality Applications
- Tumors and Oncological Cases
- Peripheral Nerve Disorders
University Children's Hospital Tübingen
2022-2025
Klinik und Poliklinik für Kinder- und Jugendmedizin
2025
Universitätsklinikum Tübingen
2021-2025
Universität Ulm
2022-2024
Heidelberg University
2015-2024
University Hospital Heidelberg
2016-2024
Zimmer Biomet (Germany)
2022
Klinikum rechts der Isar
2021
Pontifical Catholic University of Rio de Janeiro
1988
Multispectral imaging can provide reflectance measurements at multiple spectral bands for each image pixel. These be used estimation of important physiological parameters, such as oxygenation, which indicators the success surgical treatment or presence abnormal tissue. The goal this work was to develop a method estimate parameters in an accurate and rapid manner suited modern high-resolution laparoscopic images.While previous methods oxygenation are based on either simple linear complex...
Objective: Surgical data science is evolving into a research field that aims to observe everything occurring within and around the treatment process provide situation-aware data-driven assistance. In context of endoscopic video analysis, accurate classification organs in view camera proffers technical challenge. Herein, we propose new approach anatomical structure image tagging features an intrinsic measure confidence estimate its own performance with high reliability which can be applied...
Abstract The management of congenital lung malformations (CLM) remains controversial. aim this study was to analyze the timing, approach, and outcomes surgical treatment in children with CLM. A cohort conducted comparing CLM who underwent thoracoscopic resection open via thoracotomy. All were treated according an institutionalized multidisciplinary coordinated algorithm. Between 2002 2019, 68 treated. Thoracoscopic (n=44) resulted a statistically significant longer operative time (mean 169...
Desmoplastic small round cell tumor (DSRCT) is an aggressive cancer that predominantly affects adolescents and young adults, typically developing at sites lined by mesothelium [1, 2]. DSRCT genetically defined a chromosomal translocation fuses the N-terminus of EWS RNA binding protein 1 (EWSR1) to C-terminus Wilms (WT1), forming EWSR1::WT1 [3]. This fusion encodes potent transcription factor only known driver oncogenic transformation in [4]. The lack comprehensive understanding biology...
Background/Objectives: In bilateral nephroblastoma and high-risk neuroblastoma in children with extensive tumor involvement of the renal vessels or pedicle, complete resection preservation healthy tissue is not feasible situ nephron-sparing surgery vascular replacement. The aim this study was to present our experience ante autotransplantation (RATX) these children. Methods: A retrospective who underwent RATX at an international referral center for pediatric surgical oncology between 2006...
This study was conducted to evaluate the predictive values of volumetric parameters and radiomic features (RFs) extracted from pretreatment 68Ga-PSMA PET baseline clinical in response 177Lu-PSMA therapy.In this retrospective multicenter study, mCRPC patients undergoing therapy were enrolled. According outcome therapy, classified into two groups including positive biochemical (BCR) (≥ 50% reduction serum PSA value) negative BCR (< 50%). Sixty-five RFs, eight parameters, also seventeen...
Computer-assisted surgery (CAS) aims to provide the surgeon with right type of assistance at moment. Such systems are especially relevant in laparoscopic surgery, where CAS can alleviate some drawbacks that surgeons incur. For many functions, e.g. displaying location a tumor appropriate time or suggesting what instruments prepare next, analyzing surgical workflow is prerequisite. Since interventions performed via endoscope, video signal an obvious sensor modality rely on for analysis....
Intraoperative tissue classification is one of the prerequisites for providing context-aware visualization in computer-assisted minimally invasive surgeries. As many anatomical structures are difficult to differentiate conventional RGB medical images, we propose a method based on multispectral image patches. In comprehensive ex vivo study through statistical analysis, show that (1) imaging data superior organ when used conjunction with widely applied feature descriptors and (2) combining...
The goal of computer-assisted surgery is to provide the surgeon with guidance during an intervention, e.g., using augmented reality. To display preoperative data, soft tissue deformations that occur have be taken into consideration. Laparoscopic sensors, such as stereo endoscopes, can used create a three-dimensional reconstruction frames for registration. Due small field view and homogeneous structure tissue, reconstructing just one frame, in general, will not enough detail register since...
Solid tumors of the cervicothoracic junction, posterior mediastinum, or bilateral dorsal thoracic represent a challenge in pediatric surgical oncology. The aim this study was to evaluate trap-door thoracotomy and clamshell as approaches. A single-center retrospective children with solid these specific localizations performed. From 2015 2023, 26 (17 girls; 9 boys) were treated at median age 54 months (range 8–229). Tumor resection performed for neuroblastoma (n = 11); metastatic disease 7);...
Intra-operative tissue classification is one of the prerequisites for providing context-aware visualization in computer-assisted minimally invasive surgeries. As many anatomical structures are difficult to differentiate conventional RGB medical images, we propose a method based on multispectral image patches. In comprehensive <i>ex vivo</i> study show (1) that imaging data superior organ when used conjunction with widely applied feature descriptors and (2) combining texture reflectance...
Abstract Purpose Accurate laparoscopic bowel length measurement (LBLM), which is used primarily in metabolic surgery, remains a challenge. This study aims to three conventional methods for LBLM, namely using visual judgment (VJ), instrument markings (IM), or premeasured tape (PT) novel computer-assisted 3D system (BMS). Materials and Methods LBLM were compared laparoscope on phantoms regarding accuracy (relative error percent, %), time seconds (s), number of grasps. Seventy centimeters...
Abstract Purpose Surgery of complex neuroblastic tumors often requires additional procedures, especially in the situation tumor extension within thorax and impossibility securing aorta above tumor. These situations prompt opening thoracic cavity. The concern regarding increased operative trauma morbidity associated with this approach make surgeons reluctant technique. aim study was to evaluate efficacy two-cavities based on our experience a reference pediatric onco-surgical center. Methods...
Treatment of neuroblastoma metastases usually consists chemotherapy and irradiation. However, in selected cases, surgical treatment is also indicated. In this study, we present three cases patients with at rare sites that underwent surgery.We retrospectively analyzed data who surgery for our department Pediatric Surgery Urology the University Children's Hospital Tuebingen those had explicitly a metastasis.Between 2002 2020, 277 children neuroblastoma. Three exceptional are presented here...
(1) Background: The aim of this study was to investigate potential translational factors for optical 3D reconstruction in an vivo setting using a newly developed computerized bowel length measurement system (BMS) as real-time application. (2) Methods: BMS evaluated porcine experiment the influence light source power (Watt), laparoscope-to-bowel distance (cm), rotation, image background, and surgical objects image. Endpoints were robustness, calculated success rate (SR) percent, accuracy,...
Background and Objective Central serous chorioretinopathy (CSCR) is characterized by detachments of the central neurosensory retina. Besides, other alterations retinal pigment epithelium (RPE) focal detachment RPE can occur. We explored frequency double layer sign in OCT our patient population, influence subthreshold photocoagulation (ST-LP) on these parameters possibility correlations with visual acuity. Materials Methods conducted a retrospective analysis all patients who underwent ST-LP...
Since May 2021, an extension of §1631 has been implemented in Germany: gender reassignment surgery patients with differences sex development (DSD) before the capacity for self-determined consent needs interdisciplinary expert opinion and family court judge.The only exceptional cases are those which patient's health would be seriously endangered without such operation.Congenital adrenal hyperplasia (CAH) is classified to group DSD, representing one DSD-groups highest incidence.Contrary...
Neuartige Analysemethoden und eine starke Zunahme der Rechenleistung haben in den letzten Jahren ermöglicht, wertvolle Einsichten aus immer größeren Datenbeständen zu extrahieren (Big Data). Während sich Onkologie beispielsweise Genomsequenzierung neue Wege zum Verständnis von Krebserkrankungen deren personalisierter Therapie eröffneten, wird Big Data Chirurgie bisher kaum genutzt.