A5040432756- Influenza Virus Research Studies
- Vector-borne infectious diseases
- Respiratory viral infections research
- Parasites and Host Interactions
- Hepatitis C virus research
- Viral Infections and Vectors
- Hepatitis B Virus Studies
- Mosquito-borne diseases and control
- Antimicrobial Resistance in Staphylococcus
- Hepatitis Viruses Studies and Epidemiology
- Helminth infection and control
- Tuberculosis Research and Epidemiology
- Healthcare Systems and Technology
- Antibiotics Pharmacokinetics and Efficacy
- Viral Infections and Immunology Research
- Nosocomial Infections in ICU
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Healthcare Systems and Reforms
- Phenothiazines and Benzothiazines Synthesis and Activities
- Parasite Biology and Host Interactions
- Pneumonia and Respiratory Infections
- Burkholderia infections and melioidosis
- Brucella: diagnosis, epidemiology, treatment
- Blood donation and transfusion practices
- Travel-related health issues
Michigan State University
2018-2025
Lakeland Health
2017-2023
Corewell Health
2023
Corewell Health Blodgett Hospital
2021
Spectrum Health
2021
Henry Ford Hospital
2018
Mayo Clinic
2018
University of Michigan
2018
Michigan Department of Health and Human Services
2018
Lakeland Regional Medical Center
2017
Abstract Background There is a severe shortage of infectious diseases (ID) physicians in the United States, with > 80% counties without an ID physician. Insufficient compensation contributing factor, many internal medicine graduates practicing as hospitalists. Based on community needs, we merged practice into hospitalists group to create ID-Hospitalist position. Methods Corewell Health South based Berrien County, which Southwest Michigan, population 152,261, and includes large rural...
Parasite-specific humoral and cellular immune responses were evaluated in nine immunosuppressed patients with Strongyloides stercoralis infection. Four had the disseminated form of disease, five serious manifestations without evidence hyperinfection. All high levels immunoglobulin G (IgG) antibodies directed against S. larval antigens as detected by enzyme-linked immunosorbent assay. Seven both elevated total serum IgE parasite-specific a modified radioimmunoassay. The hyperinfected differed...
An outbreak of delta hepatitis occurred during 1998 among the Waorani Amazon basin Ecuador. Among 58 people identified with jaundice, 79% lived in four 22 communities. Serum B surface antigen (HBsAg) was found sera 54% jaundiced persons, and 14% asymptomatic persons. Ninety-five percent 105 had core (HBc) IgG antibody, versus 98% 51 jaundice. These data confirm that virus (HBV) infection is highly endemic Waorani. Sixteen 23 (70%) HBsAg carriers at onset epidemic serologic markers for D...
The prevalence of strongyloidiasis among American veterans the Vietnam and other wars was evaluated by testing several groups for serum IgG antibodies against Strongyloides stercoralis antigens, using an enzyme-linked immunosorbent assay. Of 493 veterans, eight (1.6%) were seropositive. 60 patients with abdominal symptoms and/or elevated eosinophilia (greater than 0.08 [greater 8%]) admitted to Cincinnati Veterans Administration Medical Center, 12 (5%) 147 residents a Administration-operated...
An outbreak of central venous catheter-associated bloodstream infections was reported in a hospital Ecuador. Commercially produced ampoules water for injection were found to be contaminated with Burkholderia cepacia and Myroides odoratus. Removal these yielded 10-fold reduction the incidence infection.
Abstract Background Recent influenza antiviral resistance studies reveal an alarming increase in both adamantanes and neuraminidase inhibitors (NAIs) resistant viral strains worldwide, particularly Asia, Europe the United States. Objectives In this study, we have evaluated virus Central South America. Methods Influenza viruses, isolated from symptomatic patients throughout America 2005–2008 were analyzed for inhibitor resistance. The M2 NA genes of viruses sequenced was inferred by...
Abstract We report an asplenic patient who was infected with Babesia divergens–like/MO-1. The clinical course complicated by multiorgan failure that required intubation and dialysis. recovered after exchange transfusion antimicrobial drug therapy. Physicians should be alert for additional cases, particularly in persons.
Forty-three hospitalized patients were treated with a new antibiotic combination containing ticarcillin plus the beta-lactamase inhibitor, clavulanic acid, in fixed for intravenous use. A variety of infections treated, including pneumonia, bacteremia, urinary tract infection, and osteomyelitis. Of 50 episodes infection 43 patients, 44 clinical cures obtained, 5 improving 1 patient failing to respond treatment. In vitro susceptibility testing 101 isolates was notable rarity resistance...
Tropical countries are thought to play an important role in the global behavior of respiratory infections such as influenza. The tropical country Ecuador has almost no documentation causes acute infections. objectives this study were identify viral agents associated with influenza like illness (ILI) Ecuador, describe what strains circulating region along their epidemiologic characteristics, and perform molecular characterization those strains.This is a prospective surveillance ILI based on...
Background Burden of disease studies intend to improve public health decision-making and measure social economic impact in population. The objective this study was describe the burden acute respiratory infections (ARI) Ecuador between 2011 2015. Methods Five-year period morbidity mortality data available from national agencies statistics analyzed estimate attributable infections. Cases deaths registered were grouped according their ICD-10 code into three diagnostic groups: Acute upper...
Military global influenza surveillance began in 1976 as an Air Force program. In 1997, the Department of Defense (DoD) Global Emerging Infections Surveillance and Response System expanded program to include all services. Also included were local residents areas where DoD overseas research activities operated. This new, worldwide infrastructure provides valuable information can respond quickly outbreaks. was demonstrated during current season when a suspected outbreak reported Panama. less...
We present a 44-year-old man from rural community in northern Ecuador who worked on cattle farm where he was involved with primary veterinary care, including assistance during births (or calving) and placenta retention artificial insemination, minimal precautions. In September of 2009, quite abruptly, developed asthenia hypersomnia without any apparent cause or symptoms like fever, chills, night sweats. On November 14, suffered pain edema the right testicle that coincided abdomen. Clinical,...
Abstract Background Eastern equine encephalitis virus is a mosquito-borne alphavirus responsible for unpredictable outbreaks of severe neurologic disease in animals and humans. While most human infections are asymptomatic or clinically nonspecific, minority patients develops encephalitic disease, devastating illness with mortality rate ≥30%. No treatments known to be effective. infection rare the United States, an annual average nationwide incidence 7 cases between 2009 2018. However, 2019,...
We report the first case of viscerotropic syndrome in Ecuador. Because similarities between yellow fever and syndrome, incidence this recently described complication vaccination with 17D vaccine is not known. There a large population South America that considered at risk for possible reemergence urban fever. Knowledge potentially fatal complications should temper decisions to vaccinate populations where disease endemic.
Wound botulism results from colonization of a contaminated wound by Clostridium botulinum and the anaerobic in situ production potent neurotoxin. Between 1943, when was first recognized, 1990, 47 laboratory-confirmed cases, mostly trauma-associated, were reported United States. Since associated with injection drug use emerged as leading cause States; 210 217 cases to Centers for Disease Control Prevention between 1990 2002 injection. Despite worldwide distribution spores, has been only twice...
Empiric antibiotics are often required in hospitalized patients with serious infections who may be septic and at risk for drug resistant organisms. The purpose of this study was to evaluate the observed incidence acute kidney injury (AKI) a sample adult receiving either piperacillin-tazobactam vancomycin or meropenemvancomycin least 72 hours.
Lyme disease is the most common tick-borne infection found in eastern United States. In recent years, it has become an emergent Michigan public health concern. carditis a recognized rare complication which classically characterized by rapidly fluctuating degrees of heart block. severe cases, or if inappropriately treated, can also result profound bradycardia, perimyocarditis, and sudden cardiac death. This report describes first documented case third degree block associated with to occur...
Objective: The objective of this study was to review the impact an automatic email notification infectious disease consultants.Design: Cases were identified from a community hospital system microbiology database by at least one positive blood culture. Records reviewed both before (2013 and 2014) after (2015 2016) implementation automated (intervention). Prior policy, consultation with (ID) specialist discretion primary team.Results: There no significant differences in 30-day mortality...
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BACKGROUND Mycobacterium avium intracellulare complex (MAI) is a member of the non-tuberculous mycobacteria family, which can cause both pulmonary and non-pulmonary disease. In patients with advanced HIV, it known to disseminated We present case 65-year-old man who has sex men (MSM) AIDS, found have spondylodiscitis an epidural abscess, had recently completed treatment for MAI. CASE REPORT The patient was AIDS secondary HIV prior history MAI, presented severe back pain. Upon presentation...
Introduction: Hepatitis B surveillance is crucial. We proposed to describe the seroprevalence of infection and associated factors among Ecuadorian Amazonia communities. Outline: A serologic cross-sectional study was carried out in subjects over two years old. classified seropositivity according Centers Diseases Control criteria recorded sex, age, temporary migration, sometime their life, previous vaccination. Results: Out 215 participants, 50.0%, 8.8%, 1.9%, 1.4% were susceptible, immune due...
Abstract Background Staphylococcus aureus is the leading cause of community and healthcare-associated bacteremia carries a high burden with substantial mortality, ranging from 20 to 40 %. Evidence suggests infectious disease (ID) consultation improves mortality adherence Infectious Diseases Society America (IDSA) guidelines. Due complications lack ID consultation, notification system consisting automated e-mails providers was implemented. The objective this study review impact automatic...