A5050718813- Neutropenia and Cancer Infections
- Central Venous Catheters and Hemodialysis
- Antifungal resistance and susceptibility
- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- Influenza Virus Research Studies
- Nosocomial Infections in ICU
- Patient Satisfaction in Healthcare
- Fungal Infections and Studies
- Sepsis Diagnosis and Treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Vaccine Coverage and Hesitancy
- Surgical site infection prevention
- Urinary Tract Infections Management
- Antibiotic Use and Resistance
- Infective Endocarditis Diagnosis and Management
- Clostridium difficile and Clostridium perfringens research
- Streptococcal Infections and Treatments
- Clinical practice guidelines implementation
- Hematological disorders and diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Multiple Myeloma Research and Treatments
- Infection Control in Healthcare
- Emergency and Acute Care Studies
- Geriatric Care and Nursing Homes
The University of Melbourne
2016-2025
Peter MacCallum Cancer Centre
2016-2025
The Royal Melbourne Hospital
2003-2025
Peter Doherty Institute
2016-2024
Victorian Aboriginal Health Service
2014-2024
Victorian Comprehensive Cancer Centre
2017-2024
Alfred Health
2013-2021
The Alfred Hospital
2016-2021
Museum of Heilongjiang Province
2021
National Health and Medical Research Council
2017-2020
We describe laboratory-confirmed influenza A pandemic (H1N1) 2009 in 17 hospitalized recipients of a hematopoietic stem cell transplant (HSCT) (8 allogeneic) and 15 patients with malignancy treated at 6 Australian tertiary centers during winter 2009. Ten (31.3%) were admitted to intensive care, 9 them HSCT recipients. All allogeneic infection <100 days posttransplantation or severe graft-versus-host disease an care unit. In-hospital mortality rate was 21.9% (7/32). The H275Y neuraminidase...
Introduction A pandemic coronavirus, SARS-CoV-2, causes COVID-19, a potentially life-threatening respiratory disease. Patients with cancer may have compromised immunity due to their malignancy and/or treatment, and be at elevated risk of severe COVID-19. Community transmission COVID-19 could overwhelm health care services, compromising delivery care. This interim consensus guidance provides advice for clinicians managing patients during the pandemic. Main recommendations During pandemic: In...
Summary An integrated antibiotic allergy testing program resulted in increased prescribing of narrow-spectrum β-lactams and reduction restricted antibiotics inappropriate prescriptions. The effectively safely de-labeled patients, with >80% labels removed following testing.
Summary We defined the epidemiology and clinical predictors of infection in patients with multiple myeloma ( MM ) receiving immunomodulatory drugs IM iDs), proteasome inhibitors PI autologous haematopoietic stem cell transplant ASCT a large longitudinal cohort study. Clinical microbiology records diagnosed between January 2008 December 2012 were reviewed to capture patient demographics, characteristics infections (type, severity, outcomes). Conditional risk set modelling was used determine...
Objectives: To report the quarterly incidence of hospital-identified Clostridium difficile infection (HI-CDI) in Australia, and to estimate burden ascribed hospital-associated (HA) community-associated (CA) infections. Design, setting patients: Prospective surveillance all cases CDI diagnosed hospital patients from 1 January 2011 31 December 2012 450 public hospitals Australian states Capital Territory. All admitted inpatient wards or units acute hospitals, including psychiatry,...
To compare risks for developing surgical site infection (SSI) due to Staphylococcus aureus when vancomycin is used antibiotic prophylaxis with a β-lactam administered prophylaxis.Vancomycin often as major surgery. In nonsurgical populations, there evidence that less effective prevention and treatment of methicillin-sensitive (MSSA) infections. Since 2002, the Victorian Healthcare Associated Surveillance System (VICNISS) has standardized methods surveillance in Australia, including any...
Antibiotic allergy testing (AAT) practices of Emerging Infections Network infectious disease physicians were surveyed. Although AAT was perceived to be necessary for removal inappropriate or unnecessary labels, there limited access any form testing. In this study, we discuss current antibiotic knowledge gaps and the development within antimicrobial stewardship programs, which will potentially improve prescribing.
Hyperglycemia in hospital inpatients without pre-existing diabetes is associated with increased mortality. However, the independent contribution of hyperglycemia to health care-associated infection (HAI), acute kidney injury (AKI), and stroke unclear.
Vancomycin-resistant enterococci (VRE) are significant nosocomial pathogens in patients with hematologic malignancy. Identification of risk factors for infection is necessary targeted prevention and surveillance.An outbreak VRE occurred at a tertiary cancer hospital between 1 August 2003 30 June 2005. Infection control measures recommended by the Society Healthcare Epidemiology America were used throughout period. A matched case-control study was performed to identify infection.Fourteen...
Abstract Administration of empiric antimicrobial therapy is standard practice in the management neutropenic fever, but there remains considerable debate about selection an optimal regimen. In view emerging evidence regarding efficacy and toxicity differences between treatment regimens, strong heterogeneity clinical practice, current guidelines were developed to provide Australian clinicians with comprehensive guidance for selecting appropriate strategy setting fever. Beta‐lactam monotherapy...
To evaluate time trends in surgical site infection (SSI) rates and SSI pathogens Australia.Prospective multicenter observational cohort study.A group of 81 Australian healthcare facilities participating the Victorian Healthcare Associated Infection Surveillance System (VICNISS).All patients underwent surgeries performed between October 1, 2002, June 30, 2013. National Safety Network surveillance methods were employed by prevention staff at hospitals.Procedure-specific risk-adjusted...
Annual influenza vaccination of healthcare workers (HCWs) is recommended in Australia, but uptake facilities has historically been low (approximately 50%). The objective this study was to develop and implement a dedicated campaign improve staff annual at large Australian health service. A quality improvement program developed Alfred Health, tertiary metropolitan service spanning 3 campuses. Pre-campaign evaluation performed by questionnaire 2013 plan multimodal strategy. Reasons for against...
Antibiotic allergy labels are associated with sub-optimal prescribing patterns and poorer clinical outcomes in non-cancer populations, but the effect of labelling on antimicrobial usage patients cancer is unknown.A retrospective review hospitalized admitted to Peter MacCallum Cancer Centre (2010-2012) identified 23 % (n = 198) an label (AA). Comparison those without demonstrated increased antibiotic use per admission (3 vs. 2, p 0.01), fluoroquinolone (11 6 %, < 0.05), course duration (15 13...