A5030511942- Infant Development and Preterm Care
- Neonatal and fetal brain pathology
- Functional Brain Connectivity Studies
- Infant Health and Development
- Schizophrenia research and treatment
- Child Nutrition and Feeding Issues
- Eating Disorders and Behaviors
- Advanced Neuroimaging Techniques and Applications
- Child and Adolescent Psychosocial and Emotional Development
- Obesity, Physical Activity, Diet
- Neonatal Respiratory Health Research
National Institute for Health Research
2020
NIHR Biomedical Research Centre at The Royal Marsden and the ICR
2020
King's College London
2013-2020
South London and Maudsley NHS Foundation Trust
2020
Kings Health Partners
2013-2015
Centre for Mental Health
2015
Alterations in cortical development and impaired neurodevelopmental outcomes have been described following very preterm (VPT) birth childhood adolescence, but only a few studies to date investigated grey matter (GM) white (WM) maturation VPT samples early adult life. Using voxel-based morphometry (VBM) we studied regional GM WM volumes 68 VPT-born individuals (mean gestational age 30 weeks) 43 term-born controls aged 19–20 years, their association with cognitive (Hayling Sentence Completion...
Very preterm birth (gestational age < 33 weeks) is associated with alterations in cortical thickness and neuropsychological/behavioural impairments. Here we studied very born individuals controls mid-adolescence (mean 15 years) beginning of adulthood 20 years), as well longitudinal changes between the two time points. Using univariate approaches, showed both increases decreases compared to controls. Specifically (1) adolescents displayed extensive areas greater thickness, especially...
Abstract This study investigates the prevalence of eating disorder (ED) psychopathology, neuropsychological function, structural brain correlates and risk mechanisms in a prospective cohort very preterm (VPT) young adults. We assessed ED psychopathology 143 individuals born at <33 weeks gestation. Structural factors birth, childhood adolescence, were investigated using prospectively collected data throughout childhood/adolescence. VPT‐born had high levels age 21 years. Executive function...
Background The hippocampus has been reported to be structurally and functionally altered as a sequel of very preterm birth (<33 weeks gestation), possibly due its vulnerability hypoxic–ischemic damage in the neonatal period. We examined hippocampal volumes subregional morphology born individuals mid- late adolescence their association with psychiatric outcome. Methods Structural brain magnetic resonance images were acquired at two time points (baseline follow-up) from 65 ex-preterm...
Individuals with psychoses have brain alterations, particularly in frontal and temporal cortices, that may be prominent, already at illness onset, those more likely to poorer symptom remission following treatment the first antipsychotic. The identification of strong neuroanatomical markers could thus facilitate stratification individualized patients schizophrenia. We used magnetic resonance imaging baseline examine regional network correlates subsequent symptomatic 167 medication-naïve or...