Claudio Vargas

ORCID: 0000-0002-8705-0873
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About
Contact & Profiles
Research Areas
  • E-Learning and Knowledge Management
  • Educational Innovations and Technology
  • Global Health Care Issues
  • Health and Lifestyle Studies
  • Asthma and respiratory diseases
  • Child Nutrition and Water Access
  • Obesity, Physical Activity, Diet
  • Indigenous Health and Education
  • Air Quality and Health Impacts
  • Educational Technology in Learning
  • Climate Change and Health Impacts
  • Gallbladder and Bile Duct Disorders
  • Healthcare Systems and Reforms
  • Educational theories and practices
  • Obstructive Sleep Apnea Research
  • Birth, Development, and Health
  • COVID-19 Pandemic Impacts
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Botulinum Toxin and Related Neurological Disorders
  • COVID-19 epidemiological studies
  • Comparative constitutional jurisprudence studies
  • Health disparities and outcomes
  • Gender, Violence, Rights in Latin America
  • Educational and Organizational Development
  • Cytokine Signaling Pathways and Interactions

Universidad de Santiago de Chile
2009-2024

University of Chile
2005-2024

Pontificia Universidad Católica de Chile
1999-2024

Advanced Center for Chronic Diseases
2020-2024

Clínica Alemana
2022

Hospital Dipreca
2019

Universidad de La Frontera
2018

Universidad de Costa Rica
1992-1995

Minnesota Department of Health
1987

The trends in mortality from aortic aneurysms the United States 1951 through 1981 were studied. Annual age-specific and age-adjusted for calculated white males, females, nonwhite females. For all four groups, a constant increase was noted period to 1968 (an average annual of 17% 12% 14% 15% females), plateauing 1968, with slight decline after 1968. corresponded an total number U.S. aneurysm deaths about 2500 approximately 14,000. most notable dissecting aneurysms. Analysis rates by birth...

10.1161/01.atv.7.6.637 article EN Arteriosclerosis An Official Journal of the American Heart Association Inc 1987-11-01

The identification of COVID-19 waves is a matter the utmost importance, both for research and decision making. This study uses information from 52 municipalities Metropolitan Region, Chile, presents quantitative method—based on weekly accumulated incidence rates—to define waves. We explore three different criteria to duration wave, performed sensitivity analysis using multivariate linear models show their commonalities differences. results that, compared benchmark definition (a 100-day...

10.3390/ijerph182111058 article EN International Journal of Environmental Research and Public Health 2021-10-21

Impact of air pollution by fine particulate matter (PM 10 ) on daily mortality in

10.4067/s0034-98872006000600012 article EN Revista médica de Chile 2006-06-01

Personal protective measures such use of face masks, hand washing and physical distancing have proven to be effective in controlling the spread Covid-19 pandemic. However, adherence these may been relaxed over time. The objective this work is assess change find factors that explain For purpose, we conducted a survey Metropolitan Region Chile which asked August-September 2021 retrospectively for 2020. With answers obtained fit logistic regression model response variable relaxation each...

10.1371/journal.pone.0267413 article EN cc-by PLoS ONE 2022-05-12

Objective: The most commonly used technique for diagnosis of diabetic neuropathy (DN) is nervous conduction (NC). Our hypothesis that the use thermal threshold (TT) to evaluate small fiber damage, which precedes large could enable earlier and diminish false negatives. Research Design Methods: study involved 70 asymptomatic patients with type 2 diabetes mellitus (T2DM) all being treated oral hypoglycemic medication, having negative metabolic control levels glycosylated hemoglobin A1c greater...

10.1177/193229681200600122 article EN Journal of Diabetes Science and Technology 2012-01-01

From 1975 to 1983, a large epidemic of typhoid fever (TF) affected the metropolitan region (MR) Chile (incidence rate [IR] 219.6 per 10 5 in 1983). In 1983–1984, interventions were implemented focusing on person-to-person transmission (vaccination, food handlers’ control, and mass communication) regulations control irrigation waters containing fecal contaminates. 1991, second intervention was quickly avoid cholera affecting neighboring countries (total prohibition growing or selling crops...

10.4269/ajtmh.18-0125 article EN cc-by American Journal of Tropical Medicine and Hygiene 2018-07-26

Why was the cohort set up?The Maule Cohort (MAUCO) is first prospective population-based of cardiovascular disease (CVD) and cancer in central Chile.The rationale for this based on social, environmental health characteristics an under-studied rural population at high risk chronic diseases. 1Chile regarded as a model social economic transition Latin America.Nevertheless, Chile's progress growth hide persistent inequalities. 2Poverty rates have declined from 38.6% 1990 to 20.7% 2017, when...

10.1093/ije/dyaa003 article EN International Journal of Epidemiology 2020-01-09

OBJETIVO:Determinar el efecto de ser indígena y la pobreza, en los problemas nutricionales escolares chilenos. MATERIAL Y MÉTODOS:Se usaron bases datos niños que ingresaron a escuela (1997-2004) tenían información antropométrica, socioeconómica origen étnico. Se construyeron modelos regresión logística para talla baja obesidad controlando pobreza etnia por sexo, edad año análisis. RESULTADOS:Se estudió 1580103 niños: indígenas (7.4%), con (2.9%) (16%). Al estratificar etnia, más pobres...

10.1590/s0036-36342009000300008 article ES cc-by-nc-sa Salud Pública de México 2009-06-01

The pattern of associations and the attributable fractions (AF) atopic conditions due to specific sensitizations vary between countries.To assess level AF sensitization five allergens in two settings.We studied 2063 Brazilians 1231 Chileans both sexes using representative samples selected at birth 1970s. Information on asthma rhinitis was based European Community Respiratory Health Survey questionnaire. We assessed bronchial hyperresponsiveness (BHR) methacholine Dermatophagoides...

10.1111/j.1365-2222.2008.03068.x article EN Clinical & Experimental Allergy 2008-07-17

Background: Latin American countries show accelerated but ethnically or socially differentiated changes in their epidemiological profiles.Aim: The present study examined the evolution of nutritional situation (1997–2005) Chilean schoolchildren as related to ethnical origin (Mapuche).Subjects and methods: Using official databases, stunting (height/age ≤ − 2 z-scores), undernutrition (body mass index (BMI) z-scores) obesity (BMI ≥95 percentile) were ascribed first-grade schoolchildren. Ethnic...

10.1080/03014460902729536 article EN Annals of Human Biology 2009-01-01

Leukaemia inhibitory factor (LIF) is a cytokine belonging to the interleukin-6 family that important at reproductive level in uterine implantation process. However, there very little evidence regarding its effect ovarian level. The aim of this work was study local involvement LIF/LIFRβ system follicular development and steroidogenesis rat ovaries. To carry out research, LIF/LIFR/GP130 transcript protein levels were measured fertile sub-fertile ovaries, vitro experiments performed assess...

10.1530/joe-22-0255 article EN Journal of Endocrinology 2023-04-20

Objective To investigate factors associated with the prevalence and incidence of gallstone disease (GSD) in women men MAUCO population-based prospective cohort. Design 8948 participants (aged 38–74 years) underwent abdominal ultrasound at baseline (2015–2019); 4385 received follow-up years 2 or 4. Factors prevalent GSD were assessed using Poisson multiple regression incident Cox models. Results was 40.4% (13.1% gallstones, 27.3% cholecystectomies) 17.1% (8.9% 8.2% cholecystectomies). In men,...

10.1136/bmjgast-2024-001457 article EN cc-by-nc BMJ Open Gastroenterology 2024-09-01

Background. An explanation of the etiology atopic conditions based on hygiene hypothesis remains controversial. Objective. To analyze exposure variables in childhood to assess their impact hay fever, asthma, and sensitization. Methods . Data were collected 1,232 young Chilean adults born between 1974 1978. Information was available consultations for infections early life, number siblings, sharing a bedroom, nursery school attendance, contact with animals first 5 years life. asthma symptoms...

10.1080/02770900701752540 article EN Journal of Asthma 2008-01-01

Several studies have shown that, in Chile, income inequality is relevant explaining health inequities. The COVID-19 pandemic has also had a negative impact, with higher mortality rates those municipalities of Greater Santiago lower socioeconomic status. We study inequity based on Potential Years Life Lost (PYLL) 34 urban the Metropolitan Region (Greater Santiago) and analyze its evolution between 2018 2021 by waves. To compare results obtained for PYLL, we computed adjusted direct...

10.1038/s41598-023-43531-x article EN cc-by Scientific Reports 2023-09-28

Summary The aims of the study were to describe trend in birthweight from 1985 2000 Chile and ascertain possible factors that may explain changes during period. We used time series length at birth all live births ( n > 4 000 000). Multivariable regression analyses carried out assess whether gender newborn, maternal education, age marital status could total by Birthweight adjusted for gestational was analysed terms grams Z scores. There an increase 100 g between 1989 1994 coincided with...

10.1111/j.1365-3016.2005.00673.x article EN Paediatric and Perinatal Epidemiology 2005-11-01

Metabolic syndrome is a risk factor for cardiovascular diseases and cancer. Its frequency increasing steadily Aim: To evaluate the prevalence of metabolic (MS) its components in 10-year tracking study young adults.Concurrent cohort subjects born between 1974 1978. They were evaluated 2000 2002 2010 2012 to determine MS (high blood glucose, waist circumference [WC], triglycerides, pressure low HDL cholesterol), according ATP III criteria. Attrition was handled using reciprocal probability...

10.4067/s0034-98872014000500005 article EN Revista médica de Chile 2014-05-01

Although polypharmacy in younger populations is a growing public health concern, most studies addressing focus on elderly populations. Thus, not yet well understood populations.Baseline data from the Maule Cohort (MAUCO) (adults aged 38-74 years) were used to study prevalence of and associated participant characteristics using logistic zero-inflated negative binomial regressions. Factors studied include age, sex, self-rated health, education, smoking, obesity, diabetes, hypertension, other...

10.1002/pds.4941 article EN Pharmacoepidemiology and Drug Safety 2020-02-10

Analizar la evolución de los nacimientos y medidas antropométricas al nacer entre 1974-2011 en el Hospital Limache, Región Valparaíso, Chile. Se construyeron series tiempo nacimientos, peso longitud nacer, talla baja nacer. modelaron las tendencias con regresiones multivariadas usándose splines para representar cambios tendencia por década. La serie comprende 17.574 nacimientos. Hubo un aumento nacimientos/año 70 (30/año) disminución 17 22 80 90 (p < 0,001); después, sin significativa. Los...

10.1016/j.rchipe.2015.06.014 article EN Revista chilena de pediatría 2015-07-01

The effects of COVID-19 in Chile changed over time and among regions.

10.4067/s0034-98872023000300269 article EN Revista médica de Chile 2023-03-01
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